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8-K/A - FORM 8-K/A - MABVAX THERAPEUTICS HOLDINGS, INC.d627535d8ka.htm

Exhibit 16.1

November 12, 2013

Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

Ladies and Gentlemen:

We have read Item 4.01(a) of Form 8-K/A dated November 12, 2013, of Telik, Inc. and are in agreement with the statements contained in the first, second, third and fourth paragraphs on page 2 therein. We have no basis to agree or disagree with other statements of the registrant contained therein.

/s/ Ernst & Young LLP