Exhibit 99.1

Select Medical Holdings Corporation Announces Results for

Third Quarter Ended September 30, 2012 and Special Cash Dividend

MECHANICSBURG, PENNSYLVANIA — November 1, 2012 — Select Medical Holdings Corporation (“Select Medical”) (NYSE: SEM) today announced results for its third quarter ended September 30, 2012.

For the third quarter ended September 30, 2012, net operating revenues increased 2.8% to $713.7 million compared to $694.1 million for the same quarter, prior year.  Income from operations increased 4.0% to $70.8 million compared to $68.1 million for the same quarter, prior year.  Net income attributable to Select Medical decreased to $24.1 million compared to $25.6 million for the same quarter, prior year.  Net income attributable to Select Medical for the three months ended September 30, 2012 includes a loss on early retirement of debt, net of tax, of $3.7 million associated with the September 12, 2012 redemption of $275.0 million of its 7 5/8% senior subordinated notes.  Net income before interest, income taxes, depreciation and amortization, gain (loss) on early retirement of debt, stock compensation expense, equity in earnings (losses) of unconsolidated subsidiaries and other income (expense) (“Adjusted EBITDA”) for the third quarter increased 1.4% to $87.7 million compared to $86.5 million for the same quarter, prior year.  A reconciliation of net income to Adjusted EBITDA is presented in table VII of this release.  Income per common share for the third quarter ended September 30, 2012 and 2011 was $0.17 on a fully diluted basis.  Excluding the loss related to the early retirement of debt and its tax effect, net income available to common stockholders on an adjusted basis, which we refer to as Adjusted Net Income Per Share, was $0.20 per diluted share for the three months ended September 30, 2012.  A reconciliation of net income per share to Adjusted Net Income Per Share is presented in table VIII of this release.

For the nine months ended September 30, 2012, net operating revenues increased 5.8% to $2,207.9 million compared to $2,086.1 million for the same period, prior year.  Income from operations increased 8.1% to $255.9 million compared to $236.7 million for the same period, prior year.  Net income attributable to Select Medical increased to $108.8 million compared to $71.0 million for the same period, prior year.  Net income attributable to Select Medical for the nine months ended September 30, 2012 includes a loss on early retirement of debt, net of tax, of $3.7 million associated with the September 12, 2012 redemption of $275.0 million of its 7 5/8% senior subordinated notes.  Net income attributable to Select Medical for the nine months ended September 30, 2011 includes a loss on early retirement of debt, net of tax, of $19.2 million associated with the June 1, 2011 refinancing of a portion of its indebtedness.  Adjusted EBITDA for the nine months ended September 30, 2012 increased 5.1% to $307.1 million compared to $292.2 million for the same period, prior year.  A reconciliation of net income to Adjusted EBITDA is presented in table VII of this release.  Income per common share for the nine months ended September 30, 2012 was $0.77 on a fully diluted basis compared to income per common share of $0.46 for the nine months ended September 30, 2011.  Excluding the loss related to the early retirement of debt in each period and their related tax effect, Adjusted Net Income Per Share was $0.79 and $0.59 per

diluted share for the nine months ended September 30, 2012 and 2011, respectively.  A reconciliation of net income per share to Adjusted Net Income Per Share is presented in table IX of this release.

Specialty Hospitals

For the third quarter of 2012, net operating revenues for the specialty hospital segment increased 2.0% to $531.4 million compared to $521.1 million for the same quarter, prior year.  Adjusted EBITDA for the specialty hospital segment increased 2.6% to $83.7 million compared to $81.6 million for the same quarter, prior year.  The Adjusted EBITDA margin for the segment was 15.7% for both the third quarter of 2012 and the same quarter, prior year. Certain specialty hospital key statistics for the third quarter periods are presented in table V of this release.

For the nine months ended September 30, 2012, net operating revenues for the specialty hospital segment increased 5.1% to $1,641.6 million compared to $1,561.3 million for the same period, prior year.  Adjusted EBITDA for the specialty hospital segment for the nine months ended September 30, 2012 increased 4.7% to $285.8 million compared to $273.0 million for the same period, prior year.  The Adjusted EBITDA margin for the segment was 17.4% for the nine months ended September 30, 2012, compared to 17.5% for the same period, prior year. Certain specialty hospital key statistics for the nine month periods are presented in table VI of this release.

Outpatient Rehabilitation

For the third quarter of 2012, net operating revenues for the outpatient rehabilitation segment increased 5.3% to $182.2 million compared to $173.0 million for the same quarter, prior year.  Adjusted EBITDA for the segment for the third quarter increased 4.7% to $20.4 million compared to $19.4 million for the same quarter, prior year.  The Adjusted EBITDA margin for the segment was 11.2% for both the third quarter of 2012 and the same quarter, prior year. Certain outpatient rehabilitation key statistics for the third quarter periods are presented in table V of this release.

For the nine months ended September 30, 2012, net operating revenues for the outpatient rehabilitation segment increased 7.9% to $566.2 million compared to $524.7 million for the same period, prior year.  Adjusted EBITDA for the segment for the nine months ended September 30, 2012 increased 5.1% to $68.7 million compared to $65.3 million for the same period, prior year.  The Adjusted EBITDA margin for the segment was 12.1% for the nine months ended September 30, 2012, compared to 12.4% for the same period, prior year. Certain outpatient rehabilitation key statistics for the nine month periods are presented in table VI of this release.

Special Cash Dividend

On October 30, 2012, Select Medical’s board of directors declared a special cash dividend of $1.50 per share, totaling approximately $210.8 million.  This special cash dividend will be paid on or about December 12, 2012 to all stockholders of record at the close of business on December 5, 2012.  “The dividend allows us to return capital to stockholders without diminishing our ability to pursue investment and acquisition opportunities,” stated Robert A. Ortenzio, Select Medical’s Chief Executive Officer.  The dividend is expected to be funded with cash on hand and borrowings under Select Medical’s existing revolving credit facility.  Select Medical anticipates using approximately $100.0 million of available cash on hand toward the funding of the dividend.  Select Medical’s leverage ratio (total debt to Adjusted EBITDA) at September 30, 2012 was 3.35, compared to 3.62 at December 31, 2011.

Stock Repurchase Program

The board of directors of Select Medical has authorized a common stock repurchase program of $250.0 million.  The program will remain in effect until March 31, 2013, unless extended by the board of directors.  Stock repurchases under this program may be made in the open market or through privately

negotiated transactions, and at times and in such amounts as Select Medical deems appropriate.  The timing of purchases of stock will be based upon market conditions and other factors.  Select Medical is funding this program with cash on hand or borrowings under its revolving credit facility.  Select Medical did not repurchase shares during the three months ended September 30, 2012.  Select Medical repurchased 5,725,782 shares at a cost of $46.8 million, which includes transaction costs, during the nine months ended September 30, 2012.  Since the inception of the program through September 30, 2012, Select Medical has repurchased 22,490,389 shares at a cost of $163.6 million, an average cost per share of $7.28, which includes transaction costs.

Business Outlook

Select Medical reaffirms its prior financial guidance for calendar year 2012.  Select Medical expects consolidated net operating revenues for the full year 2012 to be in the range of $2.9 billion to $2.975 billion.  Select Medical expects Adjusted EBITDA for the full year 2012 to be in the range of $400.0 million to $410.0 million.  Select Medical now expects fully diluted income per common share for the full year 2012 to be in the range of $0.99 to $1.04, and excluding the loss related to the early retirement of debt in the third quarter 2012 and its related tax effect, Adjusted Net Income Per Share for the full year 2012 to be in the range of $1.01 to $1.06.

Conference Call

Select Medical will host a conference call regarding its third quarter results and its business outlook on Friday, November, 2, 2012, at 9:00am EDT. The domestic dial-in number for the call is 1-866-203-3206. The international dial-in number is 1-617-213-8848. The passcode for the call is 29914018. The conference call will be webcast simultaneously and can be accessed at Select Medical Holdings Corporation’s website, www.selectmedicalholdings.com.

For those unable to participate in the conference call, a replay will be available until 11:59pm EST, November 9, 2012. The replay number is 1-888-286-8010 (domestic) or 1-617-801-6888 (international). The passcode for the replay will be 31823342. The replay can also be accessed at Select Medical Holdings Corporation’s website, www.selectmedicalholdings.com.

*   *   *   *   *

Select Medical is a leading operator of specialty hospitals and outpatient rehabilitation clinics in the United States. As of September 30, 2012, Select Medical operated 111 long term acute care hospitals and 12 acute medical rehabilitation hospitals in 28 states and 965 outpatient rehabilitation clinics in 32 states and the District of Columbia. Select Medical also provides medical rehabilitation services on a contracted basis to nursing homes, hospitals, assisted living and senior care centers, schools and work sites. Information about Select Medical is available at www.selectmedical.com.

Certain statements contained herein that are not descriptions of historical facts are “forward-looking” statements (as such term is defined in the Private Securities Litigation Reform Act of 1995).  Because such statements include risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements due to factors including the following:

·                     additional changes in government reimbursement for our services, including changes that will result from the expiration of the moratorium for long term acute care hospitals established by the Medicare, Medicaid, and SCHIP Extension Act of 2007, the American Recovery and Reinvestment Act, and the Patient Protection and Affordable Care Act may result in a reduction in net operating revenues, an increase in costs and a reduction in profitability;

·                     the failure of our specialty hospitals to maintain their Medicare certifications may cause our net operating revenues and profitability to decline;

·                     the failure of our facilities operated as “hospitals within hospitals” to qualify as hospitals separate from their host hospitals may cause our net operating revenues and profitability to decline;

·                     a government investigation or assertion that we have violated applicable regulations may result in sanctions or reputational harm and increased costs;

·                     acquisitions or joint ventures may prove difficult or unsuccessful, use significant resources or expose us to unforeseen liabilities;

·                     private third-party payors for our services may undertake future cost containment initiatives that limit our future net operating revenues and profitability;

·                     the failure to maintain established relationships with the physicians in the areas we serve could reduce our net operating revenues and profitability;

·                     shortages in qualified nurses or therapists could increase our operating costs significantly;

·                     competition may limit our ability to grow and result in a decrease in our net operating revenues and profitability;

·                     the loss of key members of our management team could significantly disrupt our operations;

·                     the effect of claims asserted against us could subject us to substantial uninsured liabilities; and

·                     other factors discussed from time to time in our filings with the Securities and Exchange Commission, including factors under the heading “Risk Factors” in our annual report on Form 10-K.

Investor inquiries:

Joel T. Veit

Vice President and Treasurer

717-972-1100

ir@selectmedical.com

SOURCE: Select Medical Holdings Corporation

I.   Condensed Consolidated Statements of Operations

For the Three Months Ended September 30, 2011 and 2012

(In thousands, except per share amounts, unaudited)

N/M = Not Meaningful

II.   Condensed Consolidated Statements of Operations

For the Nine Months Ended September 30, 2011 and 2012

(In thousands, except per share amounts, unaudited)

N/M = Not Meaningful

III.  Condensed Consolidated Balance Sheets

(In thousands, unaudited)

IV.  Condensed Consolidated Statement of Cash Flows

For the Nine Months Ended September 30, 2011 and 2012

(In thousands, unaudited)

V.  Key Statistics

For the Three Months Ended September 30, 2011 and 2012

(unaudited)

(a)         Includes managed hospitals.

(b)         Excludes managed hospitals.

(c)          Net revenue per patient day is calculated by dividing specialty hospital direct patient service revenue by the total number of patient days.

(d)         Excludes managed clinics.

(e)          Net revenue per visit is calculated by dividing outpatient rehabilitation clinic direct patient service revenue by the total number of visits.  For purposes of this computation, outpatient rehabilitation clinic direct patient service revenue does not include managed clinics or contract services revenue.

VI.  Key Statistics

For the Nine Months Ended September 30, 2011 and 2012

(unaudited)

(a)         Includes managed hospitals.

(b)         Excludes managed hospitals.

(c)          Net revenue per patient day is calculated by dividing specialty hospital direct patient service revenue by the total number of patient days.

(d)         Excludes managed clinics.

(e)          Net revenue per visit is calculated by dividing outpatient rehabilitation clinic direct patient service revenue by the total number of visits.  For purposes of this computation, outpatient rehabilitation clinic direct patient service revenue does not include managed clinics or contract services revenue.

VII. Net Income to Adjusted EBITDA Reconciliation

For the Three and Nine Months Ended September 30, 2011 and 2012

(In thousands, unaudited)

The following table reconciles net income to Adjusted EBITDA for Select Medical.  Adjusted EBITDA is used by Select Medical to report its segment performance.  Adjusted EBITDA is defined as net income before interest, income taxes, depreciation and amortization, gain (loss) on early retirement of debt, stock compensation expense, equity in earnings (losses) of unconsolidated subsidiaries and other income (expense).  The Company believes that the presentation of Adjusted EBITDA is important to investors because Adjusted EBITDA is commonly used as an analytical indicator of performance by investors within the healthcare industry.  Adjusted EBITDA is used by management to evaluate financial performance and determine resource allocation for each of its operating units.

Adjusted EBITDA is not a measure of financial performance under generally accepted accounting principles.  Items excluded from Adjusted EBITDA are significant components in understanding and assessing financial performance.  Adjusted EBITDA should not be considered in isolation or as an alternative to, or substitute for, net income, cash flows generated by operations, investing or financing activities, or other financial statement data presented in the consolidated financial statements as indicators of financial performance or liquidity.  Because Adjusted EBITDA is not a measurement determined in accordance with generally accepted accounting principles and is thus susceptible to varying calculations, Adjusted EBITDA as presented may not be comparable to other similarly titled measures of other companies.

(a)         Other primarily includes general and administrative costs.

VIII.  Reconciliation of Net Income Per Share to Adjusted Net Income Per Share

For the Three Months Ended September 30, 2011 and 2012

(In thousands, except per share amounts, unaudited)

(a)         Per share amounts for each period presented are basic weighted average common shares outstanding for all amounts except adjusted net income available to common stockholders — diluted shares, which is based on diluted shares outstanding.

(b)         Represents the estimated tax benefit on the adjustments to net income.

IX.  Reconciliation of Net Income Per Share to Adjusted Net Income Per Share

For the Nine Months Ended September 30, 2011 and 2012

(In thousands, except per share amounts, unaudited)

(a)         Per share amounts for each period presented are basic weighted average common shares outstanding for all amounts except adjusted net income available to common stockholders — diluted shares, which is based on diluted shares outstanding.

(b)         Represents the estimated tax benefit on the adjustments to net income.