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Exhibit 99.1

 

Geron Corporation Reports

2012 Second Quarter Financial Results and Events

 

MENLO PARK, Calif., July 31, 2012 — Geron Corporation (Nasdaq: GERN) today reported financial results for the three and six months ended June 30, 2012.

 

For the second quarter of 2012, the company reported a net loss of $18.3 million, or $0.14 per share, compared to $21.1 million, or $0.17 per share, for the comparable 2011 period. Net loss for the first six months of 2012 was $37.1 million, or $0.29 per share, compared to $45.5 million, or $0.37 per share, for the comparable 2011 period. The company ended the quarter with $122.3 million in cash and investments.

 

Revenues for the second quarter of 2012 were $130,000, compared to $462,000 for the comparable 2011 period. Revenues for the first six months of 2012 were $1.4 million, compared to $2.0 million for the comparable 2011 period. Revenues for the three and six month periods ended June 30, 2012 and 2011 included funding from collaboration agreements as well as royalty and license fee revenues under various agreements.

 

Total operating expenses for the second quarter of 2012 were $18.6 million, compared to $21.9 million for the comparable 2011 period. Research and development expenses for the second quarter of 2012 were $12.8 million, compared to $16.5 million for the comparable 2011 period. General and administrative expenses for the second quarter of 2012 were $5.8 million, compared to $5.3 million for the comparable 2011 period.

 

Total operating expenses for the first six months of 2012 were $38.8 million, compared to $47.7 million for the comparable 2011 period. Research and development expenses for the first six months of 2012 were $27.9 million, compared to $33.3 million for the comparable 2011 period. General and administrative expenses for the first six months of 2012 were $10.9 million, compared to $14.4 million for the comparable 2011 period.

 

The decrease in research and development expenses for the three and six month periods ending June 30, 2012, compared to the same periods in 2011, primarily reflected reduced personnel-related costs and lower scientific supplies expenses resulting from the discontinuation of the company’s stem cell programs, partially offset by increased clinical trial expenses for the enrollment of four Phase 2 clinical trials of imetelstat and two Phase 2 clinical trials of GRN1005. The increase in general and administrative expenses for the second quarter of 2012, compared to the same period in 2011, was primarily the result of higher personnel-related expenses and increased legal fees associated with the company’s intellectual property portfolio, partially offset by reduced stock-based compensation expense. The decrease in general and administrative expenses for the six months ended June 30, 2012, compared to the same period in 2011, primarily reflected a decline in personnel-related expenses associated with management transition, including non-cash stock-based compensation expense.

 



 

Non-cash operating expenses, which primarily included stock-based compensation and expenses for stock issued for services, were approximately $2.1 million and $4.4 million for the three and six month periods ended June 30, 2012, respectively, compared to $5.8 million and $15.6 million for the comparable 2011 periods.

 

Interest and other income for the second quarter of 2012 amounted to $165,000, compared to $287,000 for the comparable 2011 period. Interest and other income for the first six months of 2012 was $341,000, compared to $583,000 for the comparable 2011 period. The decline in interest and other income primarily reflected the decrease in cash and investment balances. The company has not incurred any impairment charges on its investment portfolio.

 

Clinical Programs Update

 

The second of two randomized Phase 2 clinical trials of the telomerase inhibitor, imetelstat, completed enrollment. The trial is evaluating imetelstat as maintenance therapy following platinum-based induction therapy for patients with advanced non-small cell lung cancer (NSCLC). A total of 116 patients were enrolled in the study. Geron’s other randomized Phase 2 trial of imetelstat in combination with paclitaxel in patients with locally recurrent or metastatic breast cancer (MBC) completed enrollment in the first quarter.

 

The primary objective of the NSCLC trial is to obtain an estimate of the progression-free survival (PFS) in patients receiving imetelstat as maintenance therapy. The primary objective of the MBC trial is to obtain an estimate of PFS in patients receiving imetelstat in addition to paclitaxel. Both trials require that a sufficient number of progression events accrue in order to perform the planned data analyses.

 

Geron is updating its original projections for reporting top-line data from the imetelstat MBC trial. If events continue to accrue at the current rates, Geron expects to report top-line data from the imetelstat MBC trial in the first quarter of 2013. The company continues to expect to report top-line results from its Phase 2 trials of imetelstat in NSCLC, essential thrombocythemia and multiple myeloma in the fourth quarter of 2012.

 

Both Phase 2 clinical trials for GRN1005 in brain metastases are ongoing and the company continues to expect to report top-line data from these trials by the end of the second quarter of 2013.

 

Conference Call

 

At 9:00 a.m. EDT on July 31, 2012, Geron’s management will host a conference call to discuss the company’s second quarter and year to date results and current events.

 

Participants can access the conference call via telephone by dialing 1-877-261-8990 (U.S.); 1-847-619-6441 (international). The passcode is 32983665. A live audio-only webcast is also available at http://www.media-server.com/m/acs/7146544b6cd594c58dcc4a59524bde1c. The audio webcast of the conference call will be available for replay approximately one hour following the live broadcast through August 30, 2012.

 



 

About Geron

 

Geron is a biopharmaceutical company developing first-in-class therapies for cancer. The company has two lead product candidates in clinical development, imetelstat and GRN1005. Imetelstat is a telomerase inhibitor that is being evaluated in four Phase 2 clinical trials: metastatic breast cancer, advanced non-small cell lung cancer, essential thrombocythemia/polycythemia vera and multiple myeloma. GRN1005 is a peptide-drug conjugate that is designed to transport a proven anti-cancer drug, paclitaxel, across the blood- brain barrier by targeting low-density lipoprotein receptor-related proteins (LRPs), specifically LRP-1. GRN1005 is being evaluated in two Phase 2 clinical trials: brain metastases arising from breast cancer and brain metastases arising from non-small cell lung cancer. For more information about Geron, visit www.geron.com.

 

Use of Forward-Looking Statements

 

Except for the historical information contained herein, this press release contains forward-looking statements made pursuant to the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that statements in this press release regarding Geron’s plans or expectations for or of: dates to obtain top-line data or other results from any of the Phase 2 clinical trials; and clinical development or success of imetelstat and GRN1005, constitute forward-looking statements. These statements involve risks and uncertainties that can cause actual results to differ materially from those in such forward-looking statements. These risks and uncertainties, include, without limitation: (a) regarding dates for the availability of top-line data or other results — delays in enrollment, delays caused by institutional review boards or regulatory agencies, shortage of supply, dependence on clinical trial collaborators, insufficient number of progression events and safety issues; and (b) regarding the development of imetelstat and GRN1005 — those risks and uncertainties inherent in the development of potential therapeutic products, including without limitation, successful clinical trial results and the protection of Geron’s intellectual property rights. Additional information and factors that could cause actual results to differ materially from those in the forward-looking statements are contained in Geron’s periodic reports filed with the Securities and Exchange Commission under the heading “Risk Factors,” including Geron’s quarterly report on Form 10-Q for the quarter ended March 31, 2012. Undue reliance should not be placed on forward-looking statements, which speak only as of the date they are made, and the facts and assumptions underlying the forward-looking statements may change. Except as required by law, Geron disclaims any obligation to update these forward-looking statements to reflect future information, events or circumstances.

 

CONTACT:

Anna Krassowska, Ph.D.

Investor and Media Relations

650-473-7765

investor@geron.com

media@geron.com

 

Financial table follows.

 



 

GERON CORPORATION

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

(UNAUDITED)

 

(In thousands, except share and

 

THREE MONTHS ENDED
JUNE 30,

 

SIX MONTHS ENDED
JUNE 30,

 

per share data)

 

2012

 

2011

 

2012

 

2011

 

 

 

 

 

 

 

 

 

 

 

Revenues from collaborative agreements

 

$

 

$

150

 

$

 

$

300

 

License fees and royalties

 

130

 

312

 

1,384

 

1,667

 

Total revenues

 

130

 

462

 

1,384

 

1,967

 

 

 

 

 

 

 

 

 

 

 

Operating expenses:

 

 

 

 

 

 

 

 

 

Research and development

 

12,777

 

16,544

 

27,884

 

33,299

 

General and administrative

 

5,832

 

5,334

 

10,897

 

14,440

 

Total operating expenses

 

18,609

 

21,878

 

38,781

 

47,739

 

Loss from operations

 

(18,479

)

(21,416

)

(37,397

)

(45,772

)

 

 

 

 

 

 

 

 

 

 

Unrealized gain on derivatives, net

 

8

 

240

 

34

 

279

 

Interest and other income

 

165

 

287

 

341

 

583

 

Losses recognized under equity method investment

 

 

(168

)

 

(503

)

Interest and other expense

 

(20

)

(31

)

(43

)

(64

)

Net loss

 

$

(18,326

)

$

(21,088

)

$

(37,065

)

$

(45,477

)

 

 

 

 

 

 

 

 

 

 

Basic and diluted net loss per share

 

$

(0.14

)

$

(0.17

)

$

(0.29

)

$

(0.37

)

Shares used in computing basic and diluted net loss per share

 

126,891,909

 

124,579,190

 

126,632,377

 

123,838,959

 

 

CONDENSED CONSOLIDATED BALANCE SHEETS

 

 

 

JUNE 30,

 

DECEMBER 31,

 

(In thousands)

 

2012

 

2011

 

 

 

(Unaudited)

 

(Note 1)

 

Current assets:

 

 

 

 

 

Cash, restricted cash and cash equivalents

 

$

14,917

 

$

16,898

 

Current marketable securities

 

104,050

 

105,208

 

Other current assets

 

1,878

 

3,519

 

Total current assets

 

120,845

 

125,625

 

 

 

 

 

 

 

Noncurrent marketable securities

 

3,283

 

32,133

 

Property and equipment, net

 

1,240

 

1,241

 

Deposits and other assets

 

825

 

1,048

 

 

 

$

126,193

 

$

160,047

 

 

 

 

 

 

 

Current liabilities

 

$

11,992

 

$

13,444

 

Stockholders’ equity

 

114,201

 

146,603

 

 

 

$

126,193

 

$

160,047

 

 


Note 1:

Derived from audited financial statements included in the company’s Annual Report on Form 10-K for the year ended December 31, 2011.

 

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