Exhibit 99.1

		Contact: Charles Lambert
		Finance Director
		Medical Properties Trust, Inc.
		(205) 397-8897
		clambert@medicalpropertiestrust.com

MEDICAL PROPERTIES TRUST, INC. REPORTS
SECOND QUARTER 2011 RESULTS

Total 2011 Investments of $268 Million Year-to-Date,
Including $18.0 Million Investment in Dallas-area LTACH in July

     Birmingham, AL — August 4, 2011 — Medical Properties Trust, Inc. (NYSE: MPW) today announced financial and operating results for the quarter ended June 30, 2011.

SECOND QUARTER AND RECENT HIGHLIGHTS

	•		Reported second quarter Normalized Funds from Operations (“FFO”) and Adjusted FFO (“AFFO”) per diluted share of $0.16 and $0.16, respectively;
	•		Invested $18.0 million in 40-bed LTACH in DeSoto, Texas in July;
	•		Completed previously announced refinancing and $450 million offering of unsecured notes;
	•		Completed repurchase of 85% of the $82.0 million issue of 9.25% exchangeable notes due 2013 in July;
	•		Expects $75 million investment involving the Hoboken University Medical Center to close in the third quarter;
	•		Paid 2011 second quarter cash dividend of $0.20 per share on July 14, 2011.

OPERATING RESULTS

          The Company reported second quarter 2011 Normalized FFO and AFFO of $17.5 million and $17.8 million, or $0.16 and $0.16 per diluted share, respectively. Normalized FFO and AFFO for the second quarter of 2010 were $15.8 million and $28.6 million, or $0.15 and $0.28 per diluted share, respectively. AFFO for the second quarter of 2010 included collection of $12.0 million of early payment of additional rent. All 2011 per share amounts were affected by a 7% increase in the weighted average diluted common shares outstanding to 110.6 million for the

quarter ended June 30, 2011, from 103.5 million for the same period in 2010, primarily due to the common stock offering of 29.9 million shares completed in April of 2010.

     For the six months ended June 30, 2011, Normalized FFO and AFFO were $37.9 million and $39.0 million, or $0.34 and $0.35 per diluted share, respectively. For the corresponding period in 2010, Normalized FFO and AFFO were $31.5 million and $45.5 million, or $0.35 and $0.50 per diluted share, respectively.

     A reconciliation of Normalized FFO and AFFO to net income is included in the financial tables accompanying this press release.

DIVIDEND

     The Company’s Board of Directors declared a quarterly dividend of $0.20 per share of common stock, which was paid on July 14, 2011 to stockholders of record on June 16, 2011.

LIQUIDITY

     Subsequent to the previously described refinancing transactions that were completed during the second quarter, the Company used approximately $93.0 million of proceeds to make investments in hospital real estate and operations (including $75.0 million committed to the completion of the previously described Hoboken transaction) and $82.4 million to repurchase approximately 85% of the Company’s 9.25% exchangeable notes that mature in March 2013. As of June 30, 2011, MPT held $227.9 million in cash (including the proceeds committed to Hoboken) and had available undrawn credit facilities aggregating $321.0 million. Tenants at two of MPT’s hospitals (with an aggregated net book value of $37.0 million) have indicated the intent to reacquire the real estate pursuant to the expiring leases.

PORTFOLIO UPDATE

     Subsequent to June 30, 2011, the Company acquired the real estate and an indirect 25% interest in the operations of a newly constructed long-term acute care hospital in the Dallas, Texas suburb of DeSoto.

     The Company purchased the real estate of the 40-bed, 37,000 square foot facility and 3.5 acres for $13.0 million. The hospital includes 28 medical/surgical beds and a 12-bed intensive care unit. The initial term of the 15-year net lease expires in July 2026 and has three five-year renewal options. The operator of the facility is Vibra Healthcare. MPT has also agreed to fund up to $2.5 million as a secured working capital loan to the operator and has made an indirect investment in the operating entity of $2.5 million.

     In the second quarter, the Company entered into previously described definitive agreements for a transaction involving HUMC Holdco, LLC and the Hoboken University Medical Center in New Jersey. Completion of this transaction is expected prior to the end of the

third quarter and remains subject to regulatory and bankruptcy court approval and other customary closing conditions. There is no assurance of such approvals or that the closing will occur in the third quarter or at all.

     At June 30, 2011, the Company had total real estate investments of approximately $1.4 billion comprised of 58 healthcare properties in 22 states leased to 19 hospital operating companies. Two of these investments are in the form of mortgage loans.

FUTURE OPERATIONS OUTLOOK

     Based solely on the portfolio as of June 30, 2011 and including the Hoboken and DeSoto acquisitions, the recent note offering and the tender offer for the 9.25% notes, the Company estimates that annualized Normalized FFO per share would approximate $0.72 to $0.76 per diluted share. The Company further estimates that its existing portfolio of assets plus approximately $325 million of assets expected to be acquired with available liquidity will generate Normalized FFO of between $0.93 and $0.97 per diluted share on an annualized basis once fully invested. This estimate assumes that average initial yields on new investments will range from 9.75% to 10.5%.

     These estimates do not include the effects, if any, of real estate operating costs, litigation costs, debt refinancing costs, costs of acquisitions, new interest rate hedging activities, write-offs of straight-line rent or other non-recurring or unplanned transactions; nor do they include earnings, if any, from the Company’s profits interests or other investments in lessees. In addition, this estimate will change if $325 million in new acquisitions are not completed or such investments’ average initial yields are lower or higher than the range of 9.75% to 10.5%, market interest rates change, debt is refinanced, assets are sold, the River Oaks property is leased, other operating expenses vary or existing leases do not perform in accordance with their terms.

CONFERENCE CALL AND WEBCAST

     The Company has scheduled a conference call and webcast on Thursday, August 4, 2011 at 11:00 a.m. Eastern Time to present the Company’s financial and operating results for the quarter ended June 30, 2011. The dial-in telephone numbers for the conference call are 866-730-5762 (U.S.) and 857-350-1586 (International); using passcode 64403027. The conference call will also be available via webcast in the Investor Relations’ section of the Company’s website, www.medicalpropertiestrust.com.

     A telephone and webcast replay of the call will be available from shortly after the completion through August 11, 2011. Telephone numbers for the replay are 888-286-8010 and 617-801-6888 for U.S. and International callers, respectively. The replay passcode is 35237562.

     The Company’s supplemental information package for the current period will also be available on the Company’s website under the “Investor Relations” section.

About Medical Properties Trust, Inc.

     Medical Properties Trust, Inc. is a Birmingham, Alabama based self-advised real estate investment trust formed to capitalize on the changing trends in healthcare delivery by acquiring and developing net-leased healthcare facilities. These facilities include inpatient rehabilitation hospitals, long-term acute care hospitals, regional acute care hospitals, ambulatory surgery centers and other single-discipline healthcare facilities, such as heart hospitals and orthopedic hospitals. For more information, please visit the Company’s website at www.medicalpropertiestrust.com.

# # #

MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES

Consolidated Balance Sheets

		June 30, 2011				December 31, 2010
		(Unaudited)
Assets
Real estate assets
Land, buildings and improvements, and intangible lease assets		$	1,227,250,997			$	1,032,369,288
Mortgage loans			165,000,000				165,000,000
Gross investment in real estate assets			1,392,250,997				1,197,369,288
Accumulated depreciation and amortization			(92,342,635	)			(76,094,356	)
Net investment in real estate assets			1,299,908,362				1,121,274,932
Cash and cash equivalents			227,905,625				98,408,509
Interest and rent receivable			26,676,630				26,175,635
Straight-line rent receivable			32,983,500				28,911,861
Other loans			54,978,453				50,984,904
Other assets			36,267,617				23,057,868
Total Assets		$	1,678,720,187			$	1,348,813,709
Liabilities and Equity
Liabilities
Debt, net		$	718,308,852			$	369,969,691
Accounts payable and accrued expenses			46,377,266				35,974,314
Deferred revenue			20,847,300				23,136,926
Lease deposits and other obligations to tenants			24,484,952				20,156,716
Total liabilities			810,018,370				449,237,647
Equity
Preferred stock, $0.001 par value. Authorized 10,000,000 shares; no shares outstanding			—				—
Common stock, $0.001 par value. Authorized 150,000,000 shares; issued and outstanding - 110,571,240 shares at June 30, 2011 and 110,225,052 shares at December 31, 2010			110,571				110,225
Additional paid in capital			1,055,389,297				1,051,785,240
Distributions in excess of net income			(179,930,751	)			(148,530,467	)
Accumulated other comprehensive income (loss)			(6,709,695	)			(3,640,751	)
Treasury shares, at cost			(262,343	)			(262,343	)
Total Medical Properties Trust, Inc. stockholders’ equity			868,597,079				899,461,904
Non-controlling interests			104,738				114,158
Total Equity			868,701,817				899,576,062
Total Liabilities and Equity		$	1,678,720,187			$	1,348,813,709

MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES

Consolidated Statements of Income

(Unaudited)

		For the Three Months Ended								For the Six Months Ended
		June 30, 2011				June 30, 2010				June 30, 2011				June 30, 2010
Revenues
Rent billed		$	29,108,490			$	24,311,336			$	57,781,213			$	45,559,628
Straight-line rent			2,069,633				(217,600	)			3,804,306				1,593,170
Interest and fee income			5,269,955				6,499,243				10,561,196				14,298,480
Total revenues			36,448,078				30,592,979				72,146,715				61,451,278
Expenses
Real estate depreciation and amortization			8,355,023				5,766,003				16,248,279				11,890,895
Impairment charge			564,005				—				564,005				12,000,000
Property-related			256,056				926,680				316,997				1,455,873
Acquisition expenses			616,081				884,523				2,656,053				949,163
General and administrative			7,818,054				8,579,124				14,692,315				14,684,064
Total operating expenses			17,609,219				16,156,330				34,477,649				40,979,995
Operating income			18,838,859				14,436,649				37,669,066				20,471,283
Other income (expense)
Interest and other income			20,627				29,058				6,225				13,432
Debt refinancing costs			(3,788,998	)			(6,214,211	)			(3,788,998	)			(6,214,211	)
Interest expense			(12,386,552	)			(8,556,353	)			(20,526,479	)			(18,014,081	)
Net other expense			(16,154,923	)			(14,741,506	)			(24,309,252	)			(24,214,860	)
Income (loss) from continuing operations			2,683,936				(304,857	)			13,359,814				(3,743,577	)
Income (loss) from discontinued operations			(882	)			6,537,097				147,223				7,162,417
Net income			2,683,054				6,232,240				13,507,037				3,418,840
Net income attributable to non-controlling interests			(43,409	)			(9,120	)			(87,786	)			(17,690	)
Net income attributable to MPT common stockholders		$	2,639,645			$	6,223,120			$	13,419,251			$	3,401,150
Earnings per common share — basic and diluted:
Income (loss) from continuing operations		$	0.02			$	—			$	0.12			$	(0.05	)
Income from discontinued operations			—				0.06				—				0.08
Net income attributable to MPT common stockholders		$	0.02			$	0.06			$	0.12			$	0.03
Dividends declared per common share		$	0.20			$	0.20			$	0.40			$	0.40
Weighted average shares outstanding — basic			110,589,329				103,497,945				110,494,506				91,336,728
Weighted average shares outstanding — diluted			110,600,421				103,497,945				110,504,105				91,336,728

MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES
Reconciliation of Net Income to Funds From Operations
(Unaudited)

		For the Three Months Ended								For the Six Months Ended
		June 30, 2011				June 30, 2010				June 30, 2011				June 30, 2010
FFO information:
Net income attributable to MPT common stockholders		$	2,639,645			$	6,223,120			$	13,419,251			$	3,401,150
Participating securities’ share in earnings			(281,310	)			(328,185	)			(596,670	)			(678,906	)
Net income, less participating securities’ share in earnings		$	2,358,335			$	5,894,935			$	12,822,581			$	2,722,244
Depreciation and amortization
Continuing operations			8,355,023				5,766,003				16,248,279				11,890,895
Discontinued operations			—				330,765				—				1,085,979
Loss (gain) on sale of real estate			—				(6,161,756	)			(5,324	)			(6,177,825	)
Funds from operations		$	10,713,358			$	5,829,947			$	29,065,536			$	9,521,293
Acquisition costs			616,081				884,523				2,656,053				949,163
Debt refinancing costs			3,788,998				6,214,211				3,788,998				6,214,211
Executive severance			—				2,830,221				—				2,830,221
Real estate impairment charge			564,005				—				564,005				—
Loan impairment charge			—				—				—				12,000,000
Write-off of other receivables			1,845,968				—				1,845,967				—
Normalized funds from operations		$	17,528,410			$	15,758,902			$	37,920,559			$	31,514,888
Share-based compensation			1,823,597				1,433,366				3,661,306				2,963,100
Debt costs amortization			1,011,107				1,259,000				1,998,062				2,736,390
Additional rent received in advance (A)			(300,000	)			10,000,000				(600,000	)			10,000,000
Straight-line rent revenue			(2,280,189	)			176,908				(4,014,863	)			(1,674,554	)
Adjusted funds from operations		$	17,782,925			$	28,628,176			$	38,965,064			$	45,539,824
Per diluted share data:
Net income, less participating securities’ share in earnings		$	0.02			$	0.06			$	0.12			$	0.03
Depreciation and amortization
Continuing operations			0.08				0.06				0.14				0.13
Discontinued operations			—				—				—				0.01
Loss (gain) on sale of real estate			—				(0.06	)			—				(0.07	)
Funds from operations		$	0.10			$	0.06			$	0.26			$	0.10
Acquisition costs			0.01				—				0.03				0.01
Debt refinancing costs			0.03				0.06				0.03				0.07
Executive severance			—				0.03				—				0.03
Real estate impairment charge			—				—				—				—
Loan impairment charge			—				—				—				0.14
Write-off of other receivables			0.02				—				0.02				—
Normalized funds from operations		$	0.16			$	0.15			$	0.34			$	0.35
Share-based compensation			0.02				0.02				0.03				0.03
Debt costs amortization			—				0.01				0.02				0.03
Additional rent received in advance (A)			—				0.10				—				0.11
Straight-line rent revenue			(0.02	)			—				(0.04	)			(0.02	)
Adjusted funds from operations		$	0.16			$	0.28			$	0.35			$	0.50

Funds from operations, or FFO, represents net income (computed in accordance with GAAP), excluding gains (or losses) from sales of property, plus real estate related depreciation and amortization (excluding amortization of loan origination costs) and after adjustments for unconsolidated partnerships and joint ventures. Management considers funds from operations a useful additional measure of performance for an equity REIT because it facilitates an understanding of the operating performance of our properties without giving effect to real estate depreciation and amortization, which assumes that the value of real estate assets diminishes predictably over time. Since real estate values have historically risen or fallen with market conditions, we believe that funds from operations provides a meaningful supplemental indication of our performance. We compute funds from operations in accordance with standards established by the Board of Governors of the National Association of Real Estate Investment Trusts, or NAREIT, in its March 1995 White Paper (as amended in November 1999 and April 2002), which may differ from the methodology for calculating funds from operations utilized by other equity REITs and, accordingly, may not be comparable to such other REITs. FFO does not represent amounts available for management’s discretionary use because of needed capital replacement or expansion, debt service obligations, or other commitments and uncertainties, nor is it indicative of funds available to fund our cash needs, including our ability to make distributions. Funds from operations should not be considered as an alternative to net income (loss) (computed in accordance with GAAP) as indicators of our financial performance or to cash flow from operating activities (computed in accordance with GAAP) as an indicator of our liquidity.

We calculate adjusted funds from operations, or AFFO, by subtracting from or adding to normalized FFO (i) straight-line rent revenue, (ii) non-cash share-based compensation expense, and (iii) amortization of deferred financing costs. AFFO is an operating measurement that we use to analyze our results of operations based on the receipt, rather than the accrual, of our rental revenue and on certain other adjustments. We believe that this is an important measurement because our leases generally have significant contractual escalations of base rents and therefore result in recognition of rental income that is not collected until future periods, and costs that are deferred or are non-cash charges. Our calculation of AFFO may not be comparable to AFFO or similarly titled measures reported by other REITs. AFFO should not be considered as an alternative to net income (calculated pursuant to GAAP) as an indicator of our results of operations or to cash flow from operating activities (calculated pursuant to GAAP) as an indicator of our liquidity.