Attached files

file filename
EX-10.20 - EXHIBIT 10.20 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit1020.htm
EX-10.18 - EXHIBIT 10.18 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit1018.htm
EX-10.19 - EXHIBIT 10.19 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit1019.htm
EX-31.1 - EXHIBIT 31.1 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit311.htm
EX-10.34 - EXHIBIT 10.34 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit1034.htm
EX-31.2 - EXHIBIT 31.2 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit312.htm
EX-32.1 - EXHIBIT 32.1 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit321.htm
EX-21.1 - EXHIBIT 21.1 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit211.htm
EX-10.21 - EXHIBIT 10.21 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit1021.htm
EX-10.22 - EXHIBIT 10.22 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit1022.htm
EXCEL - IDEA: XBRL DOCUMENT - VERTEX PHARMACEUTICALS INC / MAFinancial_Report.xls
10-K - 10-K - VERTEX PHARMACEUTICALS INC / MAa201410k-main.htm
EX-10.17 - EXHIBIT 10.17 - VERTEX PHARMACEUTICALS INC / MAvrtx10k_2014-exhibit1017.htm

Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the following Registration Statements:
Registration Statement (Form S-3 No. 333-186993) of Vertex Pharmaceuticals Incorporated,
Registration Statement (Form S-8 No. 333-104362) pertaining to the Vertex Pharmaceuticals 1996 Stock and Option Plan, as amended,
Registration Statement (Form S-8 Nos. 333-134482, 333-150946, 333-160442, 333-166803 and 333-184787) pertaining to the Vertex Pharmaceuticals Incorporated Amended and Restated 2006 Stock and Option Plan (formerly known as the Vertex Pharmaceuticals Incorporated 2006 Stock and Option Plan),
Registration Statement (Form S-8 No. 333-184784) pertaining to the Vertex Pharmaceuticals Incorporated Employee Stock Purchase Plan, and
Registration Statement (Form S-8 Nos. 333-188737 and 333-197466) pertaining to the Vertex Pharmaceuticals Incorporated 2013 Stock and Option Plan;

of our reports dated February 13, 2015, with respect to the consolidated financial statements of Vertex Pharmaceuticals Incorporated and the effectiveness of internal control over financial reporting of Vertex Pharmaceuticals Incorporated, included in this Annual Report (Form 10-K) of Vertex Pharmaceuticals Incorporated for the year ended December 31, 2014.

/s/ Ernst & Young LLP
    
Boston, Massachusetts
February 13, 2015