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8-K - 8-K - VERTEX PHARMACEUTICALS INC / MAa10-18206_38k.htm
EX-1.1 - EX-1.1 - VERTEX PHARMACEUTICALS INC / MAa10-18206_3ex1d1.htm
EX-25.1 - EX-25.1 - VERTEX PHARMACEUTICALS INC / MAa10-18206_3ex25d1.htm

Exhibit 12.1

 

Vertex Pharmaceuticals Incorporated

 

Computation of Ratio of Earnings to Fixed Charges

(Amounts in thousands)

 

 

 

 

 

 

 

 

 

 

 

 

 

Six Months Ended

 

 

 

Year ended December 31,

 

June 30,

 

 

 

2009

 

2008

 

2007

 

2006

 

2005

 

2010

 

Loss from continuing operations before cumulative effect of a change in accounting principle

 

$

(642,178

)

$

(459,851

)

$

(391,279

)

$

(207,937

)

$

(203,417

)

$

(365,277

)

Fixed charges:

 

 

 

 

 

 

 

 

 

 

 

 

 

Interest expense and amortization of deferred issuance costs

 

13,192

 

13,471

 

2,285

 

7,955

 

17,326

 

7,638

 

Appropriate rental obligations

 

17,827

 

14,901

 

13,520

 

15,938

 

14,736

 

9,765

 

Total fixed charges

 

$

31,019

 

$

28,372

 

$

15,805

 

$

23,893

 

$

32,062

 

$

17,403

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Loss from continuing operations before cumulative effect of a change in accounting principle, plus fixed charges

 

$

(611,159

)

$

(431,479

)

$

(375,474

)

$

(184,044

)

$

(171,355

)

$

(347,874

)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Ratio of earnings to fixed charges

 

*

 

*

 

*

 

*

 

*

 

*

 

 


*

Due to the Company’s loss from continuing operations before cumulative effect of a change in accounting principle, earnings were insufficent to cover fixed charges by $365,277,000 for the six months ended June 30, 2010 and earnings were insufficent to cover fixed charges by $642,178,000, $459,851,000, $391,279,000, $207,937,000 and $203,417,000, respectively, for the years ended December 31, 2009, 2008, 2007, 2006 and 2005.