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EXHIBIT 32.1 Certification of Periodic Financial Report by Chief Executive Officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 I, DeWitt Drew, President and Chief Executive Officer of Southwest Georgia Financial Corporation certify that: (1) The Corporation's Annual Report on Form 10-K for the annual period ended December 31, 2009 (the "Report") fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and (2) The information contained in the Report fairly present, in all material respects, the financial condition and results of operations of the Corporation. By: /s/DeWitt Drew DeWitt Drew President and Chief Executive Officer Southwest Georgia Financial Corporation March 31, 201