---

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10-Q

(Mark One)

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended: December 31, 2009
or

[   ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from _____ to _____

Commission File Number: 000-51652

ANAVEX LIFE SCIENCES CORP.
(Exact name of registrant as specified in its charter)

Nevada	20-8365999
(State or other jurisdiction of	(IRS Employer
incorporation or organization)	Identification No.)

27 Marathonos Ave., 15351 Athens, Greece
(Address of principal executive offices) (Zip Code)

30 210 603 4026
(Registrant’s telephone number, including area code)

Not Applicable
(Former name, former address and former fiscal year, if changed since last report)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of
the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant
was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.
Yes [X]    No [   ]

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if
any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405
of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit
and post such files). [   ] Yes     [   ] No

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a
smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting
company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer [   ]		Accelerated filer                    [   ]
Non-accelerated filer   [   ]	(Do not check if a smaller reporting company)	Smaller reporting company [X]

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ii

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).
Yes [   ]    No [X]

APPLICABLE ONLY TO CORPORATE ISSUERS:

Indicate the number of shares outstanding of each of the issuer’s classes of common stock, as of the latest
practicable date: 21,062,932 shares of common stock outstanding as of February 17, 2010.

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iii

TABLE OF CONTENTS

PART I - FINANCIAL INFORMATION	1
ITEM 1. FINANCIAL STATEMENTS.	1
ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS	2
Item 3. Quantitative and Qualitative Disclosures about Market Risks.	8
Item 4T. Controls and Procedures.	8
PART II - OTHER INFORMATION	9
Item 1. Legal Proceedings.	9
Item 1A. Risk Factors	9
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds	17
Item 3. Defaults upon Senior Securities.	17
Item 4. Submission of Matters to a Vote of Security Holders.	18
Item 5. Other Information	18
Item 6. Exhibits.	18
SIGNATURES	21

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1

PART I - FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS.

 

 

 

 

ANAVEX LIFE SCIENCES CORP.

(A Development Stage Company)

INTERIM CONSOLIDATED FINANCIAL STATEMENTS

December 31, 2009

(Stated in US Dollars)

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
INTERIM CONSOLIDATED BALANCE SHEETS
December 31, 2009 and September 30, 2009
(Stated in US Dollars)
(Unaudited)

ASSETS		December 31,			September 30,
		2009			2009
Current
Cash	$	21,034		$	350,994
Deferred financing charges		49,951			55,777
Prepaid expense		178			181
		71,163			406,952
Equipment		1,501			1,691
	$	72,664		$	408,643
LIABILITIES
Current
Accounts payable and accrued liabilities	$	1,570,482		$	1,591,940
Derivative liabilities – Notes 3 and 4		432,508			-
Current portion of promissory notes payable – Note 5		2,428,441			2,506,526
		4,431,431			4,098,466
Promissory notes payable – Note 5		123,981			168,000
		4,555,412			4,266,466
CAPITAL DEFICIT
Capital stock – Note 6
Authorized:
150,000,000 common shares, par value $0.001 per share
Issued and outstanding:
21,013,427 common shares (September 30, 2009: 20,746,761)		21,014			20,747
Share subscriptions received		-			300,000
Additional paid-in capital		8,762,948			8,383,663
Deficit accumulated during the development stage		(13,266,710	)		(12,562,233	)
		(4,482,748	)		(3,857,823	)
	$	72,664		$	408,643

SEE ACCOMPANYING NOTES

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
INTERIM CONSOLIDATED STATEMENTS OF OPERATIONS
for the three months ended December 31, 2009 and 2008 and
for the period from January 23, 2004 (Date of Inception) to December 31, 2009
(Stated in US Dollars)
(Unaudited)

								January 23,
								2004 (Date of
		Three months ended						Inception) to
		December 31,						December 31,
		2009			2008			2009
Expenses
Accounting and audit fees	$	21,859		$	31,260		$	234,977
Amortization		190			90			820
Bank Charges and Interest		1,715			876			22,491
Consulting fees – Notes 7 and 8(b)		454,074			515,567			6,202,076
Investor relations		54,511			25,000			458,054
Legal fees		27,908			3,610			241,028
Management fees – Note 7		-			-			14,625
Office and miscellaneous		84,728			40,640			409,266
Registration and filing fees		6,133			5,576			47,184
Rent and administration – Note 7		-			-			148,750
Research and development		211,479			284,104			4,790,453
Website design and maintenance		-			-			26,725
Loss before other item		(862,597	)		(906,723	)		(12,596,449	)
Other income (loss)
Interest		(22,802	)		(30,491	)		(135,277	)
Change in fair value of derivative liability – Note 4		649,038			-			649,038
Loss on extinguishment of promissory note		-			-			(487,469	)
Accretion of debt discount		(220,410	)		-			(390,574	)
Foreign exchange gain (loss)		8,270			9,172			(50,003	)
		414,096			(21,319	)		(414,285	)
Net loss for the period	$	(448,501	)	$	(928,042	)	$	(13,010,734	)
Basic and diluted loss per share	$	(0.02	)	$	(0.05	)
Weighted average number of shares outstanding		21,007,630			19,965,300

SEE ACCOMPANYING NOTES

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
INTERIM CONSOLIDATED STATEMENTS OF CASH FLOWS
for the three months ended December 31, 2009 and 2008 and
for the period from January 23, 2004 (Date of Inception) to December 31, 2009
(Stated in US Dollars)
(Unaudited)

								January 23,
								2004(Date of
		Three months ended						Inception) to
		December 31,						December 31,
		2009			2008			2009
Cash Flows used in Operating Activities
Net loss for the period	$	(448,501	)	$	(928,042	)	$	(13,010,734	)
Add items not involving cash:
Amortization		190			90			820
Amortization of deferred financing costs		5,826			-			5,826
Accretion of debt discount		220,410			-			390,574
Stock based compensation		112,608			200,616			2,609,730
Change in fair value of derivative liability		(649,038	)		-			(649,038	)
Consulting expense recorded in exchange for shares
to be issued		-			134,450			236,337
Common shares issued for consulting expenses		-			-			390,510
Promissory note issued for severance		-			-			71,500
Common shares issued for severance		-			-			340,600
Common shares issued for research and development
expenses		-			-			800,000
Management fees contributed		-			-			14,625
Loss on extinguishment of debt		-			-			487,469
Rent contributed		-			-			3,750
Adjustments to reconcile net loss to net cash used in
operating activities:
Prepaid expenses		3			-			(178	)
Accounts payable and accrued liabilities		(21,458	)		324,562			1,828,901
Net cash used in operating activities		(779,960	)		(268,324	)		(6,479,308	)
Cash Flows provided by Financing Activities
Issuance of common shares		300,000			-			3,433,498
Proceeds from promissory notes		150,000			134,500			2,802,500
Repayment of promissory notes		-			-			(100,000	)
Share subscriptions received		-			128,081			-
Due to related parties		-			-			33,665
Shareholder advances		-			-			333,000
Net cash provided by financing activities		450,000			262,581			6,502,663
Cash Flows used in Investing Activities
Acquisition of capital assets		-			-			(2,321	)
Increase (decrease) in cash during the period		(329,960	)		(5,743	)		21,034
Cash, beginning of period		350,994			6,357			-
Cash, end of period	$	21,034		$	614		$	21,034
Supplemental Cash Flow Information – Note 9

SEE ACCOMPANYING NOTES

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
INTERIM CONSOLIDATED STATEMENT OF CHANGES IN CAPITAL DEFICIT
for the period January 23, 2004 (Date of Inception) to December 31, 2009
(Stated in US Dollars )
(Unaudited)

														Deficit
		Common Stock												Accumulated
								Additional			Common			During the
								Paid-in			Shares to be			Development
		Shares			Par Value			Capital			Issued			Stage			Total
Capital stock issued for cash on January 23, 2004 - at $0.0033		12,000,000		$	12,000		$	28,000		$	-		$	-		$	40,000
Net loss from January 23, 2004 to September 30, 2004		-			-			-			-			(14,395	)		(14,395	)
Balance, September 30, 2004		12,000,000			12,000			28,000			-			(14,395	)		25,605
Capital stock issued for cash on December 31, 2004 - at $0.0033		7,200,000			7,200			16,800			-			-			24,000
Management fees contributed		-			-			13,000			-			-			13,000
Rent contributed		-			-			3,000			-			-			3,000
Net loss for the year		-			-			-			-			(91,625	)		(91,625	)
Balance, September 30, 2005		19,200,000			19,200			60,800			-			(106,020	)		(26,020	)
Management fees contributed – Note 7		-			-			1,625			-			-			1,625
Rent contributed – Note 7		-			-			750			-			-			750
Debt forgiven by directors – Note 7		-			-			33,666			-			-			33,666
Net loss for the year		-			-			-			-			(25,532	)		(25,532	)
Balance, September 30, 2006		19,200,000			19,200			96,841			-			(131,552	)		(15,511	)
Capital stock issued for research and development services on       September 24, 2007 - at $3.60		222,222			222			799,778			-			-			800,000
Capital stock issued for settlement of loan payable on       September 25, 2007 - at $3.60		92,500			93			332,907			-			-			333,000
Net loss for the year		-			-			-			-			(1,579,993	)		(1,579,993	)
Balance, September 30, 2007 – carried forward		19,514,722		$	19,515		$	1,229,526		$	-		$	(1,711,545	)	$	(462,504	)

SEE ACCOMPANYING NOTES

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
INTERIM CONSOLIDATED STATEMENT OF CHANGES IN CAPITAL DEFICIT
for the period January 23, 2004 (Date of Inception) to December 31, 2009
(Stated in US Dollars )
(Unaudited)

														Deficit
		Common Stock												Accumulated
								Additional			Common			During the
								Paid-in			Shares to be			Development
		Shares			Par Value			Capital			Issued			Stage			Total
Balance, September 30, 2007 – brought forward		19,514,722		$	19,515		$	1,229,526		$	-		$	(1,711,545	)	$	(462,504	)
Capital stock issued for cash on December 10, 2007 - at $3.50		150,000			150			524,850			-			-			525,000
Capital stock issued for consulting services on December 18, 2007 – at $3.86		50,000			50			192,950			-			-			193,000
Capital stock issued in settlement of debt on December 18, 2007 - at $4.50		10,000			10			44,990			-			-			45,000
Stock-based compensation for shares issued at a discount		-			-			65,000			-			-			65,000
Capital stock issued for severance on May 15, 2008 - at $5.24		65,000			65			340,535			-			-			340,600
Common stock to be issued for consulting services		-			-			-			252,599			-			252,599
Capital stock issued for consulting services on August 19, 2008 - at $5.07		25,000			25			126,725			(126,750	)		-			-
Capital stock issued for cash on August 19, 2008 - at $4.25		142,698			142			606,324			-			-			606,467
Stock based compensation – Note 6		-			-			1,493,937			-			-			1,493,937
Net loss for the year		-			-			-			-			(5,351,269	)		(5,351,269	)
Balance, September 30, 2008 – carried forward		19,957,420		$	19,957		$	4,624,838		$	125,849		$	(7,062,814	)	$	(2,292,170	)

SEE ACCOMPANYING NOTES

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
INTERIM CONSOLIDATED STATEMENT OF CHANGES IN CAPITAL DEFICIT
for the period January 23, 2004 (Date of Inception) to December 31, 2009
(Stated in US Dollars )
(Unaudited)

														Deficit
		Common Stock												Accumulated
								Additional			Common			During the
								Paid-in			Shares to be			Development
		Shares			Par Value			Capital			Issued			Stage			Total
Balance, September 30, 2008 – brought forward		19,957,420		$	19,957		$	4,624,838		$	125,849		$	(7,062,814	)	$	(2,292,170	)
Stock based compensation		-			-			812,336			-			-			812,336
Capital stock issued for consulting services on November 20, 2008 – at $2.63		25,000			25			65,725			(65,750	)		-			-
Capital stock issued for consulting services on February 20, 2009 – at $2.50		25,000			25			62,475			(62,500	)		-			-
Capital stock issued for cash on March 6, 2009 – at $2.25		89,148			89			200,494			-			-			200,583
Capital stock issued for consulting services on March 20, 2009 – at $2.00		2,500			3			4,997			-			-			5,000
Capital stock issued for cash on March 20, 2009 – at $2.25		10,800			11			24,289			-			-			24,300
Capital stock issued for cash on June 11, 2009 – at $2.25		36,000			36			80,964			-			-			81,000
Capital stock issued for services on June 11, 2009 – at $2.25		29,227			29			65,731			-			-			65,760
Capital stock issued for cash on June 19, 2009 – at $2.25		495,556			496			1,114,504			-			-			1,115,000
Capital stock issued for finders’ fees on the issuance of a promissory          note on June 26, 2009 – at $2.51		22,222			22			55,755			-			-			55,777
Shares to be issued for consulting services		-			-			-			236,337			-			236,337
Capital stock issued for cash on August 19, 2009 – at $2.25		128,888			129			289,869			-			-			289,998
Less: Finders’ fees								(72,850	)		-			-			(72,850	)
Beneficial conversion features on convertible debt issuances								333,056									333,056
Extinguishment of debt		-			-			487,469			-			-			487,469
Cancellation of common shares		(75,000	)		(75	)		234,011			(233,936	)		-			-
Share subscriptions received											300,000			-			300,000
Net loss for the year		-			-			-			-			(5,499,419	)		(5,499,419	)
Balance, September 30, 2009		20,746,761		$	20,747		$	8,383,663		$	300,000		$	(12,562,233	)	$	(3,857,823	)

SEE ACCOMPANYING NOTES

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
INTERIM STATEMENT OF STOCKHOLDER’S EQUITY (DEFICIENCY)
for the period January 23, 2004 (Date of Inception) to December 31, 2009
(Stated in US Dollars )
(Unaudited)

														Deficit
		Common Stock												Accumulated
								Additional			Common			During the
								Paid-in			Shares to be			Development
		Shares			Par Value			Capital			Issued			Stage			Total
Balance, September 30, 2009 – brought forward		20,746,761		$	20,747		$	8,383,663		$	300,000		$	(12,562,233	)	$	(3,857,823	)
Cumulative effect of accounting change – Note 3								(333,056	)					(255,976	)		(589,032	)
Capital stock issued for cash on October 2, 2009 – at $2.25		266,666			267			599,733			(300,000	)		-			300,000
Stock-based compensation – Note 8(b)		-			-			112,608			-			-			112,608
Net loss for the period		-			-			-			-			(448,501	)		(448,501	)
Balance, December 31, 2009		21,013,427		$	21,014		$	8,762,948		$	-		$	(13,266,710	)	$	(4,482,748	)

SEE ACCOMPANYING NOTES

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ANAVEX LIFE SCIENCES CORP.
(A Development Stage Company)
NOTES TO THE FINANCIAL STATEMENTS
December 31, 2009
(Stated in US Dollars)
(Unaudited)

Note 1	Nature of Operations
	The Company is in the development stage has not yet realized any revenues from its planned operations. The Company is seeking to develop and market proprietary drug targets for the treatment of cancer and diseases of the central nervous system.
	These financial statements have been prepared in accordance with generally accepted accounting principles in the United States of America on a going concern basis, which assumes that the Company will continue to realize its assets and discharge its obligations and commitments in the normal course of operations. Realization values may be substantially different from carrying values as shown and these financial statements do not give effect to adjustments that would be necessary to the carrying values and classification of assets and liabilities should the Company be unable to continue as a going concern. At December 31, 2009, the Company had an accumulated deficit of $13,266,710 (September 30, 2009 - $12,562,233) since its inception, has a working capital deficit of $4,360,268 (September 30, 2008 - $3,691,514) and expects to incur further losses in the development of its business, all of which casts substantial doubt about the Company’s ability to continue as a going concern. The Company’s ability to continue as a going concern is dependent upon its ability to generate future profitable operations and/or to obtain the necessary financing to meet its obligations and repay its liabilities arising from normal business operations when they come due. Management has no formal plan in place to address this concern but is considering obtaining additional funds by debt financing to the extent there is a shortfall from operations. Management is also negotiating amended terms of the promissory notes that have come due. While the Company is expending its best efforts to achieve the above plans, there is no assurance that any such activity will generate funds for operations.
	The Company was incorporated in the State of Nevada, United States of America on January 23, 2004 as Thrifty Printing Inc. On January 25, 2007, the Company changed its business from developing online photofinishing services to its current business and changed its name to Anavex Life Sciences Corp.
	These unaudited interim financial statements reflect all adjustments, consisting of normal recurring adjustments, which in the opinion of management are necessary for fair presentation of the information contained therein. It is suggested that these interim financial statements be read in conjunction with the audited financial statements of the Company for the year ended September 30, 2009. The interim results are not necessarily indicative of the operating results expected for the fiscal year ending on September 30, 2010. Certain information and footnote disclosures normally included in financial statements prepared in accordance with generally accepted accounting principles have been condensed or omitted pursuant to such rules and regulations, although the Company believes that the disclosures herein are adequate to make the information presented not misleading.

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Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 2

Note 2	Recent Accounting Pronouncements
	In December 2007, FASB issued guidance included in ASC 805 “Business Combinations” and ASC 810 “Accounting and Reporting of Non-controlling Interests in Consolidated Financial Statements” which requires companies to: (i) recognize, with certain exceptions, 100% of the fair values of assets acquired, liabilities assumed, and non-controlling interests in acquisitions of less than a 100% controlling interest when the acquisition constitutes a change in control of the acquired entity; (ii) measure acquirer shares issued in consideration for a business combination at fair value on the acquisition date; (iii) recognize contingent consideration arrangements at their acquisition-date fair values, with subsequent changes in fair value generally reflected in earnings; (iv) with certain exceptions, recognize pre-acquisition loss and gain contingencies at their acquisition-date fair values; (v) capitalize in-process research and development (“IPR&D”) assets acquired; (vi) expense, as incurred, acquisition-related transaction costs; (vii) capitalize acquisition-related restructuring costs only if certain criteria are met as of the acquisition date; and (viii) recognize changes that result from a business combination transaction in an acquirer’s existing income tax valuation allowances and tax uncertainty accruals as adjustments to income tax expense. The impact of ASC 805 and ASC 810 on the Company’s financial position or results of operations is dependent on whether the Company undertakes any business combinations after October 1, 2009.
	In March 2008, the FASB issued guidance included in ASC 815-10 “Derivatives and Hedging,” which seeks to enhance disclosure about how and why a company uses derivatives; how derivative instruments are accounted for and how derivatives affect a company’s financial position, financial performance and cash flows. This guidance was effective for financial statements issued for fiscal years and interim periods beginning after November 15, 2008. The adoption of this guidance did not have a material impact on the Company’s consolidated financial statements.
	In October 2009, the FASB issued ASU No. 2009-13, “Multiple-Deliverable Revenue Arrangements,” or ASU 2009-13, which amends existing revenue recognition accounting pronouncements that are currently within the scope of ASC 605. This guidance eliminates the requirement to establish the fair value of undelivered products and services and instead provides for separate revenue recognition based upon management’s estimate of the selling price for an undelivered item when there is no other means to determine the fair value of that undelivered item. ASU 2009-13 is effective prospectively for revenue arrangements entered into or materially modified in fiscal years beginning on or after June 15, 2010. The Company is currently evaluating the impact, if any, that the adoption of this amendment will have on its consolidated financial statements.
Note 3	Adoption of New Accounting Policy
	In June 2008, the Financial Accounting Standards Board (“FASB”) issued Emerging Issues Task Force (“EITF”) Issue 07-5 (EITF 07-5), “Determining Whether an Instrument (or Embedded Feature) is Indexed to an Entity’s Own Stock” which is now included in the FASB Accounting Standards Codification at ASC 815-40-15. This guidance requires entities to evaluate whether an equity-linked financial instrument (or embedded feature) is indexed to its own stock by assessing the instrument’s contingent exercise provisions and settlement provisions. Instruments not indexed to their own stock fail to meet the scope exception of Statement of Financial Accounting Standards No. 133, Accounting for Derivative Instruments and Hedging Activities, paragraph 11(a), now included in the FASB Codification at ASC 815-10-15-74(a), and should be classified as a liability and marked-to-market. ASC 815-40-15 was effective for fiscal years beginning after December 15, 2008 and thus, upon its adoption on October 1, 2009, was applied to the Company’s outstanding promissory notes.

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Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 3

Note 3	Adoption of New Accounting Policy – (cont’d)
	The Company’s outstanding promissory notes, as described in Note 5, include embedded conversion options that, prior to the adoption of this accounting policy, were not accounted for as derivative liabilities. Effective October 1, 2009, these conversion options met the criteria of a derivative instrument liability because the terms of the promissory notes require that the conversion price be adjusted in certain circumstances that do not meet the “fixed- for-fixed” criteria in ASC 815-40-15-5. As a result, the Company is now required to separately account for the embedded conversion option as a derivative instrument liability, carried at fair value and marked-to-market each period, with changes in the fair value each period charged or credited to income. The discount resulting from separating the embedded conversion feature is accreted via a charge to income using the effective yield method over the term of the debt.
	The transition provisions of ASC 815-40-15 require cumulative effect adjustments as of October 1, 2009 to reflect the amounts that would have been recognized if derivative fair value accounting had been applied from the original issuance date of an equity-linked financial instrument through the implementation date of the revised guidance. Thus, the Company calculated the value of the derivative liabilities associated with the embedded conversion features as at the date of their issuances, recorded the accretion expense applicable to the debt discount arising upon the bifurcation of the derivative liabilities and recorded the change in the fair value of the derivative liabilities from the date of the issuance of the promissory notes up to October 1, 2009. Additionally, in conjunction with the foregoing, the previously calculated amounts in respect of the beneficial conversion features and the accretion expense on the beneficial conversion debt discounts were reversed.
	The cumulative effect of this change in accounting principle of $589,032 has been recognized as an increase of the opening balance of the accumulated deficit of $255,976 and a decrease in the opening balance of additional paid-in capital of $333,056 as of October 1, 2009, with corresponding adjustments at October 1, 2009 to decrease the carrying value of the Convertible Debentures by $492,514 and the recognition of a derivative liability of $1,081,546.
Note 4	Derivative Liabilities
	Derivative liabilities, consisting of the embedded conversion features in the Company’s convertible promissory notes, are accounted for as separate liabilities measured at their respective fair values as follows:

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Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 4

Note 4	Derivative Liabilities – (cont’d)
	The fair value of the derivative liabilities has been determined using the Black-Scholes option pricing model using the following weighted average assumptions:

		December 31,	October 1,
		2009	2009
	Risk-free interest rate	0.56%	0.65%
	Expected life of derivative liability	1.02 years	1.27 years
	Annualized volatility	68.01%	69.50%
	Dividend rate	0.00%	0.00%

Note 5

Promissory Notes Payable

			December 31,			September 30,
			2009			2009
	Convertibleu non-interest bearing promissory notes	$	1,919,418		$	1,919,418
	Convertible interest bearing promissory notes		668,000			668,000
	Interesti bearing promissory note		300,000			150,000
	Non-interest bearing promissory note		100,000			100,000
	Less: beneficial conversion features		-			(333,056	)
	Less: fair value of derivative liabilities on promissory notes issuance dates		(1,074,570	)		-
	Add: accumulated accretion		639,574			170,164
			2,552,422			2,674,526
	Less: current portion		(2,428,441	)		(2,506,526	)
		$	123,981		$	168,000

Convertible non-interest bearing promissory notes

The convertible non-interest bearing promissory notes are due on demand but not before January 13, 2010 as to $150,000, February 2, 2010 as to $1,669,418 and March 16, 2010 as to $100,000. The promissory notes are convertible into units at $2.25 per unit. Each unit is comprised of one common share and one common share purchase warrant exercisable at $3.00 per share for a period of two years from the conversion date. The embedded conversion features included in these promissory notes, recorded as separate derivative liabilities along with a corresponding debt discount, were determined to have a cumulative fair value of $683,744 at their respective issuance dates. During the three months ended December 31, 2009, the Company recorded accretion expense of $203,850 on the discounts of these notes.

---

Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 5

Note 5	Promissory Notes Payable – (cont’d)
	Convertible interest bearing promissory notes
	The convertible interest bearing notes bear interest at 8% and mature on June 3, 2014, as to $500,000 and June 19, 2011, as to $168,000. The holder of the note in the amount of $500,000 may demand repayment of the balance outstanding at any time. The promissory notes are convertible into units at $2.25 per unit. Each unit is comprised of one common share and one common share purchase warrant exercisable at $3.00 per share for a period of two years from the conversion date, as to $500,000 and one common share and one-half of one common share purchase warrant exercisable at $3.50 per share for a period of one year from the conversion date, as to $168,000. The embedded conversion features included in these promissory notes, recorded as separate derivative liabilities along with a corresponding debt discount, were determined to have a cumulative fair value of $390,826 at their respective issuance dates. During the three months ended December 31, 2009, the Company recorded accretion expense of $16,560 on the discounts of these notes.
	Interest bearing promissory notes
	The Company has issued promissory notes totaling $150,000 bearing interest at 8% and it matured on December 31, 2009. On January 1, 2010, the Company issued a note with a principal balance of $157,890 (“new note”) in exchange for the $150,000 note plus accrued interest on the note which matured on December 31, 2009. The new note bears interest at 8% per annum and matures on December 31, 2010.
	During the three months ended December 31, 2009, the Company issued additional 8% interest bearing notes totaling $150,000 which mature on December 5, 2010 as to $50,000 and December 22, 2010 as to $100,000.
	Non- interest bearing promissory note
	Pursuant to a termination agreement the Company has issued one non-interest bearing promissory note to a former officer of the Company, in the amount of $200,000. The Company has repaid $100,000 and, as at December 31, 2009 and September 30, 2009, the Company was in default of the payment terms for the remaining $100,000 balance owing. Subsequent to December 31, 2009, the Company and the former officer agreed to settle the outstanding amount owed by issuing 49,505 common shares of the Company at their fair value of $2.02 per share.
Note 6	Capital Stock
	On May 24, 2006, the board of directors approved a six (6) for one (1) forward split of the authorized issued and outstanding common stock. The Company’s authorized capital increased from 25,000,000 shares of common stock to 150,000,000 shares of common stock.
	On September 24, 2007, the Company issued 222,222 common shares common shares at $3.60 per share for a total of $800,000 for research and development expenses. The common shares were recorded based upon the quoted market price of the Company’s common stock on the agreement date.

---

Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 6

Note 6	Capital Stock – (cont’d)
	On September 25, 2007, the Company settled a loan payable in the amount of $333,000 by issuing 92,500 common shares at $3.60 per share, being the quoted market price of the Company’s common stock on the settlement date.
	On December 10, 2007, the Company issued 150,000 units at $3.50 per unit for proceeds of $525,000. Each unit consisted of one common share and one common share purchase warrant entitling the holder to purchase an additional common share at $5.00 per share until December 10, 2009.
	On December 18, 2007, the Company issued 10,000 shares at $4.50 per share for a total of $45,000 pursuant to an agreement to settle a debt and issued 50,000 shares at $3.86 per share for a total of $193,000 pursuant to a consulting agreement. The Company recorded compensation expense of $65,000 in respect of these issuances based on the excess of the fair value of these shares over the balances at which they were recorded by the Company.
	On May 15, 2008, the Company issued 65,000 common shares at $5.24 per share for a total of $340,600 to its former CEO in accordance with the terms of a severance agreement upon the termination of his services. The common shares were recorded based upon the quoted market price of the Company’s common stock on the agreement date.
	On August 19, 2008, the Company issued 25,000 common shares at $5.07 per share for a total of $ 126,750 to a director of the Company pursuant to an agreement to provide consulting services. The common shares were recorded based upon the quoted market price of the Company’s common stock on the agreement date.
	On August 19, 2008, the Company issued 142,698 units at $4.25 per unit for proceeds of $606,467 pursuant to private placement agreements. Each unit consisted of one common share and one common share purchase warrant entitling the holder to purchase an additional common share at $5.00 per share until August 19, 2009.
	On November 20, 2008, the Company issued 25,000 common shares at $2.63 per share for a total of $65,750 to a director of the Company pursuant to an agreement to provide consulting services. The common shares were recorded based upon the quoted market price of the Company’s common stock on the issuance date.
	On February 20, 2009, the Company issued 25,000 common shares at $2.50 per share for a total of $62,500 to a director of the Company pursuant to an agreement to provide consulting services. The common shares were recorded based upon the quoted market price of the Company’s common stock on the issuance date.
	On March 6, 2009, the Company issued 89,148 units at $2.25 per unit for proceeds of $200,583 pursuant to private placement agreements. Each unit consisted of one common share and one common share purchase warrant entitling the holder to purchase an additional common share at $4.00 per share until March 6, 2010.
	On March 20, 2009, the Company issued 10,800 units at $2.25 per unit for proceeds of $24,300 pursuant to private placement agreements. Each unit consisted of one common share and one common share purchase warrant entitling the holder to purchase an additional common share at $4.00 per share until March 20, 2010.
	On March 20, 2009, the Company issued 2,500 common shares at $2.00 per share for a total of $5,000 to a public relations consultant pursuant to an agreement to provide consulting services. The common shares were recorded based upon the quoted market price of the Company’s common stock on the issuance date.

---

Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 7

Note 6	Capital Stock – (cont’d)
	On May 14, 2009, the Company entered into a revised consulting agreement with a director whereby the consultant returned 75,000 common shares to the Company for cancellation. The return of shares was recorded at their par value.
	On June 11, 2009 the Company issued 36,000 units at $2.25 per unit for proceeds of $81,000 pursuant to private placement agreements. Each unit consisted of one common share and one common share purchase warrant entitling the holder to purchase an additional common share at $4.00 per share until June 11, 2010. The Company paid finders’ fees in the amount of $8,100 in relation to this private placement.
	On June 11, 2009 the Company issued 29,227 common shares at $2.25 per share for service rendered by consultants. The common shares were recorded based upon the quoted market price of the Company’s common stock on the issuance date.
	On June 19, 2009 the Company issued 495,556 units at $2.25 per unit for proceeds of $1,115,000 pursuant to private placement agreements. Each unit consisted of one common share and one and one- eighth common share purchase warrant entitling the holder to purchase an additional common share at $2.25 per share until June 19, 2011. The Company paid finders’ fees in the amount of $55,750 in relation to this private placement.
	On June 26, 2009, the Company issued 22,222 common shares at $2.51 per share for a total value of $55,777 for finders’ fees related to the issuance of the $500,000 promissory note (Note 5). The common shares were recorded based upon the quoted market price of the Company’s common stock on the issuance date. Such amount has been deferred and is being amortized over the term of the debt.
	On August 19, 2009, the Company issued 128,888 units at $2.25 per Unit for total proceeds of $289,998. Of these placements, 40,000 Units consisted of one common share and one share purchase warrant entitling the holder to purchase an additional common share at $4.00 per share until July 10, 2010 and 88,888 Units consisted on one common share and one and one- eighth share purchase warrant entitling the holder to purchase an additional common shares at $2.25 per share until August 4, 2011. The Company paid finders’ fees totaling $9,000 in respect of these private placements.
	On October 2, 2009 the Company issued 266,666 units at $2.25 per unit for proceeds of $600,000 pursuant to private placement agreements. Each unit consisted of one common share and one and one- eighth common share purchase warrant entitling the holder to purchase an additional common share at $2.25 per share until October 2, 2011.
Note 7	Related Party Transactions
	During the three months ended December 31, 2009 and 2008 the Company was charged consulting fees from officers and a private company owned by a director as follows:

			Three months			Three months
			ended			ended
			December 31,			December 31,
			2009			2008
	Consulting	$	170,657		$	67,959

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Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 8

Note 7	Related Party Transactions – (cont’d)
	The following amounts were contributed to the Company by the directors and officers of the Company:

									January 23,
			Three Months			Three Months			2004 (Date of
			ended			ended			Inception) to
			December 31,			December 31,			December 31
			2009			2008			2009
	Management fees	$	-		$	-		$	14,625
	Rent		-			-			3,750
	Debt forgiven by directors		-			-			33,666
		$	-		$	-		$	52,041

	At December 31, 2009, included in accounts payable and accrued liabilities is $71,006 (September 30, 2009: $57,464) owed to a director and an officer of the Company in respect of unpaid consulting fees.
Note 8	Commitments

	a)	Share Purchase Warrants
		A summary of the Company’s share purchase warrants outstanding is presented below:

			Number of			Exercise
			Shares			Price
	Balance, September 30, 2008		292,698			$5.00
	Expired		(142,695	)		$5.00
	Issued		833,448			$2.62
	Balance, September 30, 2009		983,448			$2.93
	Expired		(150,000	)		$5.00
	Issued		299,999			$2.25
	Balance, December 31, 2009		1,133,447			$2.52

At December 31, 2009 the Company has 1,133,447 currently exercisable share purchase warrants outstanding as follows:

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Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 9

Note 8

Commitments – (cont’d)

	b)	Stock-based Compensation Plan
		A summary of the status of the company’s outstanding stock purchase options for the three months ended December 31, 2009 is as follows:

						Weighted
						Average
			Number of			Exercise
			Shares			Price
	Outstanding at September 30, 2008		1,420,000			$4.44
	Granted		1,775,000			$2.51
	Outstanding at September 30, 2009 and December 31, 2009		3,195,000			$3.37
	Exercisable at December 30, 2009		1,380,000			$4.31
	Exercisable at September 30, 2009		1,330,000			$4.38

At December 31, 2009, the following stock options were outstanding:

	1.	As at December 31, 2009, these options have not vested. The options vest upon the Company listing its shares on the American Stock Exchange or any other nationally recognized stock exchange by December 1, 2012 or in the event of a change of control and a listing on a nationally recognized stock exchange is not required. No stock-based compensation has been recorded in the financial statements as the performance condition has not yet been met.
	2.	As at December 31, 2009 and September 30, 2009, these options have fully vested. The Company recognized $320,752 stock-based compensation for the options vested in the year ended September 30, 2008. The Company recognized $40,020 included with consulting fees in respect of the remainder of the options that vested during the year ended September 30, 2009.

---

Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 10

Note 8

Commitments – (cont’d)

	b)	Stock-based Compensation Plan – (cont’d)
		3.	As at December 31, 2009 and September 30, 2009, these options have fully vested. The fair value of the options on the grant date was calculated to be $122,150 which amount has been recognized as stock-based compensation for the year ended September 30, 2008.
		4.	As at December 31, 2009 and September 30, 2009, these options have fully vested. The Company recognized stock-based compensation in the amount of $256,954 in the financial statements for the year ended September 30, 2008. The Company has recognized stock-based compensation in the amount of $12,956 included with consulting fees in respect of the remainder of the options that vested during the year ended September 30, 2009.
		5.	As at December 31, 2009 and September 30, 2009, these options have fully vested. The Company recognized stock-based compensation in the amount of $794,081 in the financial statements for the year ended September 30, 2008. The Company recognized stock-based compensation in the amount of $341,354 included with consulting fees in respect of the remainder of the options that vested during the year ended September 30, 2009.
		6.	These options were granted during the year ended September 30, 2009 and as at December 31, 2009, 25,000 of these options had vested. The remaining 25,000 options vested on January 13, 2010. The grant date fair value of these options was calculated to be $79,000 of which the Company has included $56,509 in consulting fees for the year ended September 30, 2009. The Company has recognized stock-based compensation in the amount of $2,950 included with consulting fees in the financial statements for the three months ended December 31, 2009.
		7.	As at December 31, 2009 and September 30, 2009, these options have fully vested. The Company recognized stock-based compensation of $6,000 included with consulting fees in the financial statements for the year ended September 30, 2009.
		8.	As at December 31, 2009, 300,000 of these options have vested. The remaining 100,000 options vest as to 50,000 on each of February 14, 2010 and May 14, 2010. The grant date fair value of these options was calculated to be $544,000 of which the Company has recognized stock- based compensation in the amount of $238,063, included with consulting fees in the financial statements for the year ended September 30, 2009. The Company has recognized stock-based compensation in the amount of $37,158 included with consulting fees in the financial statements for the three months ended December 31, 2009.
		9.	As at December 31, 2009 these options have not vested. During the three months ended December 31, 2009, the vesting provisions of these options were changed such that there are 100,000 options vesting for each compound entering Phase II trials. The fair value of these options was calculated to be $740,000, which the Company has not yet recognized in the financial statements as the performance conditions have not yet been met.
		10.	As at December 31, 2009 these options have not vested. The options vest 233,333 on each of June 10, 2010, one compound commencing Phase 2 trials and one compound commencing Phase 3 trial. The fair value of these options was calculated to be $1,099,000 of which the Company has recognized stock-based compensation in the amount of $117,434, included with consulting fees in the financial statements for the year ended September 30, 2009. The Company has recognized stock-based compensation in the amount of $72,500 included with consulting fees in the financial statements for the three months ended December 31, 2009.
		11.	As at December 31, 2009 these options have not vested. The options vest upon completion of a minimum financing of $3,000,000 introduced and closed by the optionee. No stock-based compensation has been recorded in the financial statements as the performance conditions have not yet been met.

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Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 11

Note 8

Commitments – (cont’d)

	b)	Stock-based Compensation Plan – (cont’d)
		12.	As at December 31, 2009 these options have not vested. The options vest upon one or more compounds: entering Phase 2 Trial – 90,000 options; entering Phase 3 Trial – 90,000 options; and receiving FDA approval – 90,000 options. No stock-based compensation has been recorded in the financial statements as none of the performance conditions have yet been met.

The fair value of stock options granted has been determined using the Black-Scholes option pricing model using the following weighted average assumptions applied to stock options granted or re-priced during the periods:

		December 31,	September 30,
		2009	2009
	Risk-free interest rate	1.79%	1.07%
	Expected life of options	3.99 years	2.42 years
	Annualized volatility	88.54%	73.61%
	Dividend rate	0%	0%

The volatility was determined based on an index of volatility from comparable companies. The expected term of the options granted to employees is derived from the simplified method as prescribed by SEC Staff Accounting Bulletin No. 110 given that the Company has no historical experience with the exercise of options for which to base an estimate of the expected term of options granted. The Company anticipates it will discontinue the use of the simplified method of SAB 110 once sufficient historical option exercise behavior becomes apparent. The expected term of options granted to non-employees was determined to be the option term.

At December 31, 2009, the following summarizes the unvested stock options:

						Weighted			Weighted
						Average			Average
			Number of			Exercise			Grant-date
			Shares			Price			Fair value
	Unvested options at September 30, 2009		1,865,000		$	2.65		$	2.93
	Vested		(50,000	)	$	2.50		$	3.44
	Unvested options at December 31, 2009		1,815,000		$	2.65		$	3.01

As at December 31, 2009, there was a total of $191,390 of unrecognized compensation cost associated with unvested share-based compensation awards that will become vested exclusive of achieving any performance milestones. This unrecognized compensation cost is expected to be recognized in the year ended September 30, 2010. There has been no stock-based compensation recognized in the financial statements for the period ended December 31, 2009 for options that vest upon the achievement of performance milestones because the Company has determined that satisfaction of the performance milestones was not probable. Compensation relating to stock options exercisable upon achieving performance milestones will be recognized in the period the milestones are achieved.

---

Anavex Life Sciences Corp.
(A Development Stage Company)
Notes to the Consolidated Financial Statements
December 31, 2009
(Stated in US Dollars)
Unaudited – Page 12

Note 8

Commitments – (continued)

	b)	Stock-based Compensation Plan
		Stock-based compensation amounts, including those relating to shares issued for non-cash consideration during the period, are classified in the Company’s Statement of Operations as follows:

			2009			2008
	Consulting	$	112,608		$	335,066

Note 9	Supplemental Cash flow Information
	Investing and financing activities that do not have a direct impact on current cash flows are excluded from the statements of cash flows.
	During the period ended December 31, 2008, the Company issued 25,000 common shares at $2.63 per share for a total of $65,750 in respect of payment for consulting services.
Note 10	Subsequent Events
	The Company has evaluated subsequent events from December 31, 2009 up to February 22, 2010, the date on which the financial statements are filed as required by ASC 855.

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2

ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Forward-Looking Statements

This quarterly report contains forward-looking statements. All statements other than statements of historical facts contained in this quarterly report, including statements regarding our anticipated future clinical and regulatory milestone events, future financial position, business strategy and plans and objectives of management for future operations, are forward looking statements. These statements relate to future events or our future financial performance. In some cases, you can identify forward-looking statements by terminology such as “may”, “should”, “expect”, “plan”, “anticipate”, “believe”, “estimate”, “predict”, “potential” or “continue” or the negative of these terms or other comparable terminology. Such forward-looking statements include, without limitation, statements regarding the anticipated start dates, durations and completion dates of our ongoing and future clinical studies, statements regarding the anticipated designs of our future clinical studies, statements regarding our anticipated future regulatory submissions and statements regarding our anticipated future cash position. We have based these forward-looking statements largely on our current expectations and projections about future events, including the responses we expect from the U.S. Food and Drug Administration, or FDA, and other regulatory authorities and financial trends that we believe may affect our financial condition, results of operations, business strategy, preclinical and clinical trials and financial needs. These statements are only predictions and involve known and unknown risks, uncertainties and other factors, including the risks in the section entitled “Risk Factors” that may cause our company’s or our industry’s actual results, levels of activity, performance or achievements to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements.

Moreover, we operate in a very competitive and rapidly changing environment. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. You should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Except as required by applicable law, including the securities laws of the United States, we do not intend to update any of the forward-looking statements to conform these statements to actual results.

Our financial statements are stated in United States dollars and are prepared in accordance with United States generally accepted accounting principles.

In this quarterly report, unless otherwise specified, all dollar amounts are expressed in United States dollars and all references to “common shares” refer to the shares of our common stock.

As used in this quarterly report, the terms “we”, “us”, “our”, and “Anavex” mean Anavex Life Sciences Corp., unless the context clearly requires otherwise.

Our Business

We are a biopharmaceutical company engaged in the discovery and development of novel drug targets to treat serious diseases for which there are urgent unmet medical needs. The ANAVEX portfolio involves new sigma receptor compounds (ligands) in the preclinical stage that target neurodegenerative diseases and cancer. Our lead drug candidate ANAVEX 2-73, targeting Alzheimer’s disease (AD), is expected to enter first Human Clinical Trials (HCT) by mid 2010. Scale-up manufacturing of ANAVEX 2-73 has been completed and Forenap Pharma EURL has been contracted to carry out our phase 1 clinical trials. We have completed most preclinical testing on ANAVEX 2-73 and are currently preparing the Investigational New Drug (IND) file. In parallel, we plan to launch HCT for another three of our compounds (melanoma, prostate cancer and epilepsy) in 2010 provided sufficient capital is available. Additionally, we intend to further develop compounds in earlier preclinical phases, which target diseases like diabetes, depression, neuropathic pain and various types of cancer and continue to develop and expand our Sigmaceptor^tm platform.

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3

Our proprietary SIGMACEPTOR™ Discovery Platform has resulted in and continues to generate small molecule drug candidates with unique modes of action, by making use of sigma receptors, which represent potential targets for therapeutic developments in combating many human diseases (such as Alzheimer’s disease, depression, epilepsy and cancer). When activated by the appropriate ligands, these receptors influence the functioning of multiple biochemical signals that are involved in the pathogenesis (origin or development) of a disease.

With our SIGMACEPTOR™-N program, we are focused on developing disease modifying treatments for CNS diseases using sigma-1 receptor ligands. Among our lead CNS drug candidates, we have made significant progress with ANAVEX 2-73, our lead drug candidate to treat Alzheimer’s disease (“AD”), and ANAVEX 19-144, another lead drug candidate to treat epilepsy. Preclinical data reveals that these compounds exhibit significant anti-amnesic, neuroprotective and anticonvulsant properties in a variety of in vitro systems and specialized animal models. These activities involve sigma-1 and NMDA receptor components and also ion channels, indicating a unique mode of action. In AD, ANAVEX 2-73 is pharmacologically suggested as an effective neuroprotective, anti-convulsive and anti depressive (anti-amnesic) putative therapeutic agent, due to its potent affinity to sigma-1 receptors and moderate affinities to M1-4 types muscarinic receptors. In epilepsy, ANAVEX 19-144 controls seizures and the epileptogenesis process. Moreover, its neuroprotective properties prevent the process that causes long-term damage to tissue and cells as well as biochemical and physiological alterations to the brain from epileptic seizures.

We also have reported promising developments with ANAVEX 1-41, which is a sigma-1 agonist and a lead compound to treat AD and depression. Preclinical tests revealed significant neuroprotective benefits (i.e. protects nerve cells from degeneration or death) through the prevention of oxidative stress, which damages and destroys cells and is believed to be a primary cause of AD. In addition, ANAVEX 1-41 prevented the expression of caspase-3, an enzyme that plays a key role in apoptosis (programmed cell death) and in the loss of cells in the hippocampus, the part of the brain that regulates learning, emotion and memory. These activities involve both muscarinic andsigma-1 receptor systems through a novel mechanism of action. Via this novel mechanism of action, it is anticipated that ANAVEX 1-41 may offer disease-modifying options that reverse memory and learning deficits and protect nerve cells from death through its anti-amnesic, neuroprotective and anxiolytic actions. ANAVEX 1-41 may slow the progression of AD and considerably improve the quality of life of those impacted by the disease as well as their caregivers.

Our SIGMACEPTOR™-C program leverages the unique properties of sigma-1 and/or sigma-2 receptor ligands, which allows us to create a potent class of promising drug candidates designed to combat various types of solid cancer. Sigma receptors are highly expressed in different tumor cell types and binding by appropriate sigma-1 and/or sigma-2 ligands can induce selective apoptosis. In addition, through tumor cell membrane reorganization and interactions with ion channels, our drug candidates are believed to play an important role in inhibiting the processes of metastasis (spreading of cancer cells from the original site to other parts of the body), angiogenesis (the formation of new blood vessels) and tumor cell proliferation. The compounds in our oncology program are in pre-clinical testing, and there is no guarantee that the activity demonstrated in pre-clinical models will be shown in human testing.

ANAVEX 7-1037, our lead drug candidate for the treatment of prostate cancer, is a low molecular weight, synthetic compound exhibiting high (nanomolar) affinity for sigma-1 and moderate (micromolar) affinity for sigma-2 and sodium channels. In advanced preclinical studies, this compound revealed antitumor potential with no toxic side effects. It has also been shown to selectively kill human cancer cells without affecting normal/healthy cells and also to significantly suppress tumor growth in immune-deficient mice models. Scientific publications emphasize the promise of sigma receptor ligands, highlighting the fact that these ligands stop tumor growth and induce selective cell death in various tumor cell lines, including leukemia, melanoma and cancers of the colon, breast, prostate, lung, brain, ovary and kidney.

Numerous additional compounds are currently in the early discovery and lead optimization stages of our SIGMACEPTOR™-N and SIGMACEPTOR™-C programs.

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4

Results of Operations

Revenue

We have not earned any revenues since our inception on January 23, 2004. We are still in the development stage and do not anticipate earning any revenues until we can establish an alliance with targeted companies to market or distribute the results of our research projects.

Expenses

Our expenses for the three months ended December 31, 2009 and 2008 were as follows:

Three Months Ended December 31, 2009 and 2008

Expenses for the three months ended December 31, 2009 decreased by $44,126 over the same period in 2008. Bank charges and Interest increased to $1,715 for the three months ended December 31, 2009 from $876 for the same period in 2008 due to an increased amount of interest bearing promissory notes. Consulting fees decreased from $515,567 for the three months ended December 31, 2008 to $454,074 for the same period in 2009 primarily as a result of decreased stock based compensation charges. Legal fees increased to $27,908 for the three months ended December 31, 2009 from $3,610 for the same period in 2008 primarily as a result of increased patent and corporate activity fees. Research and Development charges decreased to $211,479 for the three months ended December 31, 2009 from $284,104 for the same period in 2008 resulting from decreased research activities.

Other Income and loss

Other income and (loss) for the three months ended December 31, 2009, were $414,096 as compared to a loss of $(21,319) for the comparable three months ended December 31, 2008. The increase of $435,415 is primarily attributable to the change in fair value of the derivative liability of $649,038 and a foreign exchange gain of $8,270. These were offset by accretion of discounts on notes payable of $220,410 and interest expense of $22,802.

Change in fair value of derivative liability

We recognized a gain on derivative financial instruments of $ 649,038 for the three months ended December 31, 2009, as compared to $ Nil for the prior year’s comparable period, The non-cash gain arises from adjusting the embedded conversion feature of our convertible promissory notes payable to fair value at each reporting period in accordance with current accounting standards. The embedded conversion features of the convertible promissory notes are treated as derivative liabilities because the conversion price can be adjusted in certain circumstances.

We use the Black-Scholes option pricing model to estimate the fair value of this derivative. Because the Black-Scholes model uses our stock price as one of the inputs in calculating the fair value of the derivative liabilities, changes in the stock price will result in volatility in the earnings in future periods as we continue to reflect the derivative financial instruments at fair value.

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Liquidity and Capital Resources

Working Capital

As of December 31, 2009, we had $21,034 in cash, a decrease of $329,960 from September 30, 2009. The principal component of this decrease in cash was draw downs on the cash for general working purposes. As of December 31, 2009, we had a working capital deficit of $4,360,268, an increase of $668,754 from September 30, 2009. The principal component of this increase in working capital deficit was a decrease in our current assets.

On October 2, 2009 we issued an aggregate of 266,666 units of our securities at a purchase price of $2.25 per unit. Each unit consists of one share of common stock in the capital of our company and 1.125 common share purchase warrants. One full warrant entitles the holder to purchase one additional share of common stock at a price of $2.25 per warrant share for a period of two years.

We anticipate that we will require up to $10 million for the 12 months ending December 31, 2010 to implement our plan of operation of researching and developing our patents, the related compounds and any further intellectual property we may acquire. The majority of our capital resources requirement is needed to enter ANAVEX 2-73, ANAVEX 1-41 and ANAVEX 7-1037 into clinical trials. If we are not able to secure additional financing, we will not be able to implement and fund these trials.

Cash Flows

		Three Months Ended			Three Months Ended
		December 31, 2009			December 31, 2008
Cash flows used in operating activities	$	(779,960	)		(268,324	)
Cash flows from financing activities	$	450,000			262,581
Cash flows from investing activities	$	-			-
Increase (decrease) in cash	$	(329,960	)		(5,743	)

Cash flow used in operating activities

Our cash used in operating activities for the three months ended December 31, 2009 compared to our cash used in operating activities for the three months ended December 31, 2008 increased by 191%. This change was largely due to a net decrease in accounts payable for the three months ended December 31, 2009 in the amount of $21,459 compared to a net increase of accounts payable for the three months ended December 31, 2008 in the amount of $324,562 for a total difference of $346,021.

Cash flow provided by financing activities

Our cash provided by financing activities for the three months ended December 31, 2009 compared to our cash provided by financing activities for the three months ended December 31, 2008 increased by 71% largely due to promissory notes issued in the quarter.

Cash Provided by Investing Activities

No cash was used in or provided by investing activities for the three months ended December 31, 2009 or 2008.

Going Concern

At December 31, 2009, we had an accumulated deficit of $13,266,710 since our inception and expect to incur further losses in the development of our business, all of which casts substantial doubt about our ability to continue as a going concern. Our ability to continue as a going concern is dependent upon our ability to generate future profitable operations and/or to obtain the necessary financing to meet our obligations and repay our liabilities arising

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from normal business operations when they come due. Our independent auditors included an explanatory paragraph regarding substantial doubt about our ability to continue as a going concern in their report on our annual financial statements for the year ended September 30, 2009.

Future Financing

We will require additional financing to fund our planned operations, including researching and developing our patents, the related compounds and any further intellectual property that we may acquire and entering some of our current compounds into clinical trials. We currently do not have committed sources of additional financing and may not be able to obtain additional financing, particularly, if the volatile conditions in the stock and financial markets, and more particularly the market for early development stage biotechnology research and development company stocks persist.

There can be no assurance that additional financing will be available to us when needed or, if available, that it can be obtained on commercially reasonable terms. If we are not able to obtain the additional financing on a timely basis, if and when it is needed, we will be forced to delay or scale down some or all of our research and development activities or perhaps even cease the operation of our business.

Since inception we have funded our operations primarily through equity and debt financings and we expect that we will continue to fund our operations through the equity and debt financing. If we raise additional financing by issuing equity securities, our existing stockholders’ ownership will be diluted. Obtaining commercial loans, assuming those loans would be available, will increase our liabilities and future cash commitments.

There is no assurance that we will be able to maintain operations at a level sufficient for an investor to obtain a return on his, her, or its investment in our common stock. Further, we may continue to be unprofitable.

Off-Balance Sheet Arrangements

We have no off-balance sheet arrangements that have or are reasonably likely to have a current or future effect on our financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity, capital expenditures or capital resources that is material to our stockholders.

Application of Critical Accounting Policies

Our financial statements and accompanying notes are prepared in accordance with generally accepted accounting principles in the United States. Preparing financial statements requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue and expenses. These estimates and assumptions are affected by management’s application of accounting policies. We believe that understanding the basis and nature of the estimates and assumptions involved with the following aspects of our financial statements is critical to an understanding of our financials.

We base our assumptions and estimates on historical experience and other sources that we believe to be reasonable at the time. Actual results may vary from our estimates due to changes in circumstances, weather, politics, global economics, mechanical problems, general business conditions and other factors. Our significant estimates are related to the valuation of warrants and options.

There are accounting policies that we believe are significant to the presentation of our financial statements. The most significant of these accounting policies relates to the accounting for our research and development expenses and stock-based compensation expense.

Research and Development Expenses

Research and developments costs are expensed as incurred. These expenses are comprised of the costs of our proprietary research and development efforts, including salaries, facilities costs, overhead costs and other related expenses as well as costs incurred in connection with third-party collaboration efforts. Milestone payments to third parties are expensed when the specific milestone has been achieved.

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In addition, we incur expenses in respect of the acquisition of intellectual property relating to patents and trademarks. The probability of success and length of time to developing commercial applications of the drugs subject to the acquired patents and trademarks is difficult to determine and numerous risks and uncertainties exist with respect to the timely completion of the development projects. There is no assurance the acquired patents and trademarks will ever be successfully commercialized. Due to these risks and uncertainties, we expense the acquisition of patents and trademarks.

Stock-based Compensation

We account for all of our stock-based payments and awards under the fair value based method.

Stock-based payments to non-employees are measured at the fair value of the consideration received, or the fair value of the equity instruments issued, or liabilities incurred, whichever is more reliably measurable. The fair value of stock-based payments to non-employees is periodically re-measured until the counterparty performance is complete, and any change therein is recognized over the vesting period of the award and in the same manner as if we had paid cash instead of paying with or using equity based instruments. The cost of the stock-based payments to non-employees that are fully vested and non-forfeitable as at the grant date is measured and recognized at that date, unless there is a contractual term for services in which case such compensation would be amortized over the contractual term.

We account for the granting of share purchase options to employees using the fair value method whereby all awards to employees will be recorded at fair value on the date of the grant. The fair value of all share purchase options are expensed over their vesting period with a corresponding increase to additional capital surplus. Upon exercise of share purchase options, the consideration paid by the option holder, together with the amount previously recognized in additional capital surplus, is recorded as an increase to share capital.

We use the Black-Scholes option valuation model to calculate the fair value of share purchase options at the date of the grant. Option pricing models require the input of highly subjective assumptions, including the expected price volatility. Changes in assumptions can materially affect the fair value estimate and therefore the Black-Scholes model does not necessarily provide a reliable single measure of the fair value of our share purchase options.

Derivative Liabilities

We evaluate the embedded conversion features of our convertible promissory notes to determine whether they are indexed to our stock for purposes of determining whether are required to be bifurcated as separate derivative liabilities. When they are determined not to be indexed to our stock, and thus classified as derivative liabilities, they are marked-to-market each reporting period.

We use the Black-Scholes option pricing model to calculate the fair value of the derivative liabilities at each reporting period. The Black Scholes pricing model requires the input of highly subjective assumptions, including the expected price volatility. Changes in assumptions can materially affect the fair value estimate and therefore the Black-Scholes model does not necessarily provide a reliable single measure of the fair value of our derivative liabilities.

The summary of significant accounting policies should be read in conjunction with our consolidated financial statements and related notes and management’s discussion and analysis of financial condition and results of operations.

Recent accounting pronouncements

In December 2007, FASB issued guidance included in ASC 805 “Business Combinations” and ASC 810 “Accounting and Reporting of Non-controlling Interests in Consolidated Financial Statements” which requires companies to: (i) recognize, with certain exceptions, 100% of the fair values of assets acquired, liabilities assumed, and non-controlling interests in acquisitions of less than a 100% controlling interest when the acquisition constitutes a change in control of the acquired entity; (ii) measure acquirer shares issued in consideration for a business combination at fair value on the acquisition date; (iii) recognize contingent consideration arrangements at their

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acquisition-date fair values, with subsequent changes in fair value generally reflected in earnings; (iv) with certain exceptions, recognize pre-acquisition loss and gain contingencies at their acquisition-date fair values; (v) capitalize in-process research and development (“IPR&D”) assets acquired; (vi) expense, as incurred, acquisition-related transaction costs; (vii) capitalize acquisition-related restructuring costs only if certain criteria are met as of the acquisition date; and (viii) recognize changes that result from a business combination transaction in an acquirer’s existing income tax valuation allowances and tax uncertainty accruals as adjustments to income tax expense. The impact of ASC 805 and ASC 810 on the Company’s financial position or results of operations is dependent on whether the Company undertakes any business combinations after October 1, 2009.

In March 2008, the FASB issued guidance included in ASC 815-10 “Derivatives and Hedging,” which seeks to enhance disclosure about how and why a company uses derivatives; how derivative instruments are accounted for and how derivatives affect a company’s financial position, financial performance and cash flows. This guidance was effective for financial statements issued for fiscal years and interim periods beginning after November 15, 2008. The adoption of this guidance did not have a material impact on the Company’s consolidated financial statements.

In October 2009, the FASB issued ASU No. 2009-13, “Multiple-Deliverable Revenue Arrangements,” or ASU 2009-13, which amends existing revenue recognition accounting pronouncements that are currently within the scope of ASC 605. This guidance eliminates the requirement to establish the fair value of undelivered products and services and instead provides for separate revenue recognition based upon management’s estimate of the selling price for an undelivered item when there is no other means to determine the fair value of that undelivered item. ASU 2009-13 is effective prospectively for revenue arrangements entered into or materially modified in fiscal years beginning on or after June 15, 2010. The Company is currently evaluating the impact, if any, that the adoption of this amendment will have on its consolidated financial statements.

Item 3. Quantitative and Qualitative Disclosures about Market Risks.

Not Applicable.

Item 4T. Controls and Procedures.

Disclosure Controls and Procedures

As required by Rule 13a-15 under the Securities Exchange Act of 1934, our management, with the participation of our principal executive officer and our principal financial officer, evaluated our disclosure controls and procedures (as defined in Rules 13a-15(e) of the Securities Exchange Act of 1934) as of the end of the period covered by this quarterly report on Form 10-Q. Disclosure controls and procedures are controls and other procedures that are designed to ensure that information required to be disclosed in our reports filed or submitted under the Securities Exchange Act of 1934 is recorded, processed, summarized and reported, within the time periods specified in the Securities and Exchange Commission’s rules and forms. Disclosure controls and procedures include controls and procedures designed to ensure that information required to be disclosed in our reports filed under the Securities Exchange Act of 1934 is accumulated and communicated to our principal executive officer and our principal financial officer to allow timely decisions regarding required disclosure.

Based on that evaluation, our management, with the participation of our principal executive officer and our principal financial officer, concluded that as of the end of the period covered by this quarterly report on Form 10-Q, our disclosure controls and procedures were not effective. The ineffectiveness of our disclosure controls and procedures was due to the weaknesses disclosed in our annual report on Form 10-K filed on December 24, 2009.

We intend to take appropriate and reasonable steps to make the necessary improvements to remediate these deficiencies at some time in the future. This will depend on our financial position and the management’s determination of which changes should be made and when. We intend to consider the results of our remediation efforts and related testing as part of our year-end 2010 assessment of the effectiveness of our internal control over financial reporting.

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Changes in Internal Control over Financial Reporting

We have not made any changes in our internal control over financial reporting during the fiscal quarter ended December 31, 2009 that have materially affected, or are reasonably likely to materially affect our internal control over financial reporting.

PART II - OTHER INFORMATION

Item 1. Legal Proceedings.

We know of no material, existing or pending legal proceedings to which we are a party or of which any of our properties is the subject. In addition, we do not know of any such proceedings contemplated by any governmental authorities. We know of no proceedings in which any of our directors, officers or affiliates, or any registered or beneficial stockholder is a party adverse to our company or has a material interest adverse to our company.

Item 1A. Risk Factors.

In addition to other information in this quarterly report, the following risk factors should be carefully considered in evaluating our business because such factors may have a significant impact on our business, operating results, liquidity and financial condition. As a result of the risk factors set forth below, actual results could differ materially from those projected in any forward-looking statements. Additional risks and uncertainties not presently known to us, or that we currently consider to be immaterial, may also impact our business, operating results, liquidity and financial condition. If any such risks occur, our business, operating results, liquidity and financial condition could be materially affected in an adverse manner. Under such circumstances, the trading price of our securities could decline, and you may lose all or part of your investment.

Risks Related to our Company

We have had a history of losses and no revenue, which raise substantial doubt about our ability to continue as a going concern.

Since inception on January 23, 2004, we have an accumulated deficit of $13,266,710 from operations. We can offer no assurance that we will ever operate profitably or that we will generate positive cash flow in the future. To date, we have not generated any revenues from our operations. Our history of losses and no revenues raise substantial doubt about our ability to continue as a going concern. We will not be able to generate significant revenues in the future and our management expects acquisitions and exploration expenditures and operating expenses to increase substantially over the next 12 months. As a result, our management expects the business to continue to experience negative cash flow for the foreseeable future and cannot predict when, if ever, our business might become profitable. We will need to raise additional funds, and such funds may not be available on commercially acceptable terms, if at all. If we are unable to raise funds on acceptable terms, we may not be able to execute our business plan, take advantage of future opportunities, or respond to competitive pressures or unanticipated requirements. This may seriously harm our business, financial condition and results of operations.

We are an early development stage biotechnology research and development company and may never be able to successfully develop marketable products or generate any revenue. We have a very limited relevant operating history upon which an evaluation of our performance and prospects can be made. There is no assurance that our future operations will result in profits. If we cannot generate sufficient revenues, we may suspend or cease operations.

We are an early development stage company and have not generated any revenues to date and have no operating history. All of our potential drug compounds are in the concept stage and have not undergone significant testing in non-clinical studies or in clinical trials. Moreover, we cannot be certain that our research and development efforts will be successful or, if successful, that our potential drug compounds will ever be approved for sales to pharmaceutical companies or generate commercial revenues. We have no relevant operating history upon which an evaluation of our performance and prospects can be made. We are subject to all of the business risks associated with

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a new enterprise, including, but not limited to, risks of unforeseen capital requirements, failure of potential drug compounds either in non-clinical testing or in clinical trials, failure to establish business relationships and competitive disadvantages as against larger and more established companies. If we fail to become profitable, we may suspend or cease operations.

We will need additional funding and may be unable to raise additional capital when needed, which would force us to delay, reduce or eliminate our research and development activities.

We will need to raise additional funding, but the current economic crisis and its impact on the stock markets will most likely have a negative impact on our ability to raise additional needed capital on terms that are favorable to our company or at all. We do not anticipate that we will generate significant revenues for several years, if at all. Until we can generate significant revenues, if ever, we expect to satisfy our future cash needs through equity or debt financing. We cannot be certain that additional funding will be available on acceptable terms, or at all. If adequate funds are not available, we may be required to delay, reduce the scope of, or eliminate one or more of our research and development activities.

We may be unable to continue as a going concern in which case our securities will have little or no value.

Our independent auditors have noted in their report concerning our annual financial statements as of September 30, 2009 that we have incurred substantial losses since inception, which raises substantial doubt abut our ability to continue as a going concern. In the event we are not able to continue operations you will likely suffer a complete loss of your investment in our securities.

Risks Related to our Business

Even if we are able to develop our potential drug compounds, we may not be able to receive regulatory approval, or if approved, we may not be able to generate significant revenues or successfully commercialize our products, which will adversely affect our financial results and financial condition and we will have to delay or terminate some or all of our research and development plans and we may be forced to cease operations.

All of our potential drug compounds will require extensive additional research and development, including non-clinical testing and clinical trials, as well as regulatory approvals, before we can market them. We cannot predict if or when any of the potential drug compounds we intend to develop will be approved for marketing. There are many reasons that we may fail in our efforts to develop our potential drug compounds. These include:

• the possibility that non-clinical testing or clinical trials may show that our potential drug compounds are ineffective and/or cause harmful side effects;

• our potential drug compounds may prove to be too expensive to manufacture or administer to patients;

• our potential drug compounds may fail to receive necessary regulatory approvals from the United States Food and Drug Administration or foreign regulatory authorities in a timely manner, or at all;

• even if our potential drug compounds are approved, we may not be able to produce them in commercial quantities or at reasonable costs;

• even if our potential drug compounds are approved, they may not achieve commercial acceptance;

• regulatory or governmental authorities may apply restrictions to any of our potential drug compounds, which could adversely affect their commercial success; and

• the proprietary rights of other parties may prevent us or our potential collaborative partners from marketing our potential drug compounds.

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If we fail to develop our potential drug compounds, our financial results and financial condition will be adversely affected, we will have to delay or terminate some or all of our research and development plans and may be forced to cease operations.

Our research and development plans will require substantial additional future funding which could impact our operational and financial condition. Without the required additional funds, we will likely cease operations.

It will take several years before we are able to develop marketable potential drug compounds, if at all. Our research and development plans will require substantial additional capital, arising from costs to:

• conduct research, non-clinical testing and human studies;

• establish pilot scale and commercial scale manufacturing processes and facilities; and

• establish and develop quality control, regulatory, marketing, sales, finance and administrative capabilities to support these programs.

Our future operating and capital needs will depend on many factors, including:

• the pace of scientific progress in our research and development programs and the magnitude of these programs;

• the scope and results of preclinical testing and human studies;

• the time and costs involved in obtaining regulatory approvals;

• the time and costs involved in preparing, filing, prosecuting, maintaining and enforcing patent claims;

• competing technological and market developments;

• our ability to establish additional collaborations;

• changes in our existing collaborations;

• the cost of manufacturing scale-up; and

• the effectiveness of our commercialization activities.

We base our outlook regarding the need for funds on many uncertain variables. Such uncertainties include the success of our research initiatives, regulatory approvals, the timing of events outside our direct control such as negotiations with potential strategic partners and other factors. Any of these uncertain events can significantly change our cash requirements as they determine such one-time events as the receipt or payment of major milestones and other payments.

Additional funds will be required to support our operations and if we are unable to obtain them on favorable terms, we may be required to cease or reduce further research and development of our drug product programs, sell some or all of our intellectual property, merge with another entity or cease operations.

If we fail to demonstrate efficacy in our non-clinical studies and clinical trials our future business prospects, financial condition and operating results will be materially adversely affected.

The success of our research and development efforts will be greatly dependent upon our ability to demonstrate potential drug compound efficacy in non-clinical studies, as well as in clinical trials. Non-clinical studies involve testing potential drug compounds in appropriate non-human disease models to demonstrate efficacy and safety. Regulatory agencies evaluate these data carefully before they will approve clinical testing in humans. If certain non-clinical data reveals potential safety issues or the results are inconsistent with an expectation of the potential drug compound’s efficacy in humans, the regulatory agencies may require additional more rigorous testing, before

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allowing human clinical trials. This additional testing will increase program expenses and extend timelines. We may decide to suspend further testing on our potential drug compounds if, in the judgment of our management and advisors, the non-clinical test results do not support further development.

Moreover, success in non-clinical testing and early clinical trials does not ensure that later clinical trials will be successful, and we cannot be sure that the results of later clinical trials will replicate the results of prior clinical trials and non-clinical testing. The clinical trial process may fail to demonstrate that our potential drug compounds are safe for humans and effective for indicated uses. This failure would cause us to abandon a drug candidate and may delay development of other potential drug compounds. Any delay in, or termination of, our non-clinical testing or clinical trials will delay the filing of an investigational new drug application and new drug application with the Food and Drug Administration and, ultimately, our ability to commercialize our potential drug compounds and generate product revenues. In addition, we expect that our clinical trials will involve small patient populations. Because of the small sample size, the results of these early clinical trials may not be indicative of future results.

Following successful non-clinical testing, potential drug compounds will need to be tested in a clinical development program to provide data on safety and efficacy prior to becoming eligible for product approval and licensure by regulatory agencies. From the first human trial through product approval can take many years and 10-12 years is not unusual.

If any of our future clinical development potential drug compounds become the subject of problems, our ability to sustain our development programs will become critically compromised. For example, efficacy or safety concerns may arise, whether or not justified, that could lead to the suspension or termination of our clinical programs. Examples of problems that could arise include, among others:

• efficacy or safety concerns with the potential drug compounds, even if not justified;

• unexpected side-effects;

• regulatory proceedings subjecting the potential drug compounds to potential recall;

• publicity affecting doctor prescription or patient use of the potential drug compounds;

• pressure from competitive products; or

• introduction of more effective treatments.

Each clinical phase is designed to test attributes of the drug and problems that might result in the termination of the entire clinical plan can be revealed at any time throughout the overall clinical program. The failure to demonstrate efficacy in our clinical trials would have a material adverse effect on our future business prospects, financial condition and operating results.

If we do not obtain the support of qualified scientific collaborators, our revenue, growth and profitability will likely be limited, which would have a material adverse effect on our business.

We will need to establish relationships with leading scientists and research institutions. We believe that such relationships are pivotal to establishing products using our technologies as a standard of care for various indications. Additionally, although in discussion, there is no assurance that our current research partners will continue to work with us or that we will be able to attract additional research partners. If we are not able to establish scientific relationships to assist in our research and development, we may not be able to successfully develop our potential drug compounds. If this happens, our business will be adversely affected.

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We may not be able to develop market or generate sales of our products to the extent anticipated. Our business may fail and investors could lose all of their investment in our company.

Assuming that we are successful in developing our potential drug compounds and receiving regulatory clearances to market our products, our ability to successfully penetrate the market and generate sales of those products may be limited by a number of factors, including the following:

• If our competitors receive regulatory approvals for and begin marketing similar products in the United States, the European Union, Japan and other territories before we do, greater awareness of their products as compared to ours will cause our competitive position to suffer;

• Information from our competitors or the academic community indicating that current products or new products are more effective than our future products could be, if and when they are generated, impede our market penetration or decrease our future market share; and,

• The price for our future products, as well as pricing decisions by our competitors, may have an effect on our revenues.

If this happens, our business will be adversely affected.

None of our potential drug compounds may reach the commercial market for a number of reasons and our business may fail.

Successful research and development of pharmaceutical products is high risk. Most products and development candidates fail to reach the market. Our success depends on the discovery of new drug compounds that we can commercialize. It is possible that our potential drug compounds may never reach the market for a number of reasons. They may be found ineffective or may cause harmful side-effects during non-clinical testing or clinical trials or fail to receive necessary regulatory approvals. We may find that certain potential drug compounds cannot be manufactured at a commercial scale and, therefore, they may not be economical to produce. Our potential drug compounds could also fail to achieve market acceptance or be precluded from commercialization by proprietary rights of third parties. Furthermore, we do not expect our potential drug compounds to be commercially available for a number of years, if at all. If none of our potential drug compounds reach the commercial market, our business will likely fail and investors will lose all of their investment in our company. If this happens, our business will be adversely affected.

If our competitors succeed in developing products and technologies that are more effective than our own, or if scientific developments change our understanding of the potential scope and utility of our potential drug compounds, then our technologies and future potential drug compounds may be rendered undesirable or obsolete.

We face significant competition from industry participants that are pursuing technologies similar to those that we are pursuing and are developing pharmaceutical products that are competitive with our potential drug compounds. Nearly all of our industry competitors have greater capital resources, larger overall research and development staffs and facilities, and a longer history in drug discovery and development, obtaining regulatory approval and pharmaceutical product manufacturing and marketing than we do. With these additional resources, our competitors may be able to respond to the rapid and significant technological changes in the biotechnology and pharmaceutical industries faster than we can. Our future success will depend in large part on our ability to maintain a competitive position with respect to these technologies. Rapid technological development, as well as new scientific developments, may result in our potential drug compounds becoming obsolete before we can recover any of the expenses incurred to develop them. For example, changes in our understanding of the appropriate population of patients who should be treated with a targeted therapy like we are developing may limit the drug’s market potential if it is subsequently demonstrated that only certain subsets of patients should be treated with the targeted therapy.

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Our reliance on third parties, such as university laboratories, contract manufacturing organizations and contract or clinical research organizations, may result in delays in completing, or a failure to complete, non-clinical testing or clinical trials if they fail to perform under our agreements with them.

In the course of product development, we may engage university laboratories, other biotechnology companies or contract or clinical manufacturing organizations to manufacture drug material for us to be used in non-clinical and clinical testing and contract research organizations to conduct and manage non-clinical and clinical studies. If we engage these organizations to help us with our non-clinical and clinical programs, many important aspects of this process have been and will be out of our direct control. If any of these organizations we may engage in the future fail to perform their obligations under our agreements with them or fail to perform non-clinical testing and/or clinical trials in a satisfactory manner, we may face delays in completing our clinical trials, as well as commercialization of any of our potential drug compounds. Furthermore, any loss or delay in obtaining contracts with such entities may also delay the completion of our clinical trials, regulatory filings and the potential market approval of our potential drug compounds.

If we fail to compete successfully with respect to acquisitions, joint venture and other collaboration opportunities, we may be limited in our ability to research and develop our potential drug compounds.

Our competitors compete with us to attract established biotechnology and pharmaceutical companies or organizations for acquisitions, joint ventures, licensing arrangements or other collaborations. Collaborations include contracting with academic research institutions for the performance of specific scientific testing. If our competitors successfully enter into partnering arrangements or license agreements with academic research institutions, we will then be precluded from pursuing those specific opportunities. Since each of these opportunities is unique, we may not be able to find a substitute. Other companies have already begun many drug development programs, which may target diseases that we are also targeting, and have already entered into partnering and licensing arrangements with academic research institutions, reducing the pool of available opportunities.

Universities and public and private research institutions also compete with us. While these organizations primarily have educational or basic research objectives, they may develop proprietary technology and acquire patents that we may need for the development of our potential drug compounds. We will attempt to license this proprietary technology, if available. These licenses may not be available to us on acceptable terms, if at all. If we are unable to compete successfully with respect to acquisitions, joint venture and other collaboration opportunities, we may be limited in our ability to develop new products.

The use of any of our potential drug compounds in clinical trials may expose us to liability claims, which may cost us a significant amounts of money to defend against or pay out, causing our business to suffer.

The nature of our business exposes us to potential liability risks inherent in the testing, manufacturing and marketing of our potential drug compounds. We currently do not have any potential drug compounds in clinical trials, however, when any of our potential drug compounds enter into clinical trials or become marketed products they could potentially harm people or allegedly harm people and we may be subject to costly and damaging product liability claims. Some of the patients who participate in clinical trials are already critically ill when they enter a trial. The waivers we obtain may not be enforceable and may not protect us from liability or the costs of product liability litigation. Although we intend to obtain product liability insurance that we believe is adequate, we are subject to the risk that our insurance will not be sufficient to cover claims. The insurance costs along with the defense or payment of liabilities above the amount of coverage could cost us significant amounts of money, causing our business to suffer.

The patent positions of biopharmaceutical products are complex and uncertain and we may not be able to protect our patented or other intellectual property. If we cannot protect this property, we may be prevented from using it or our competitors may use it and our business could suffer significant harm. Also, the time and money we spend on acquiring and enforcing patents and other intellectual property will reduce the time and money we have available for our research and development, possibly resulting in a slow down or cessation of our research and development.

We own patents related to certain of our potential drug compounds. However, these patents do not ensure the protection of our intellectual property for a number of reasons, including the following:

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	1.	Competitors may interfere with our patent process in a variety of ways. Competitors may claim that they invented the claimed invention prior to us. Competitors may also claim that we are infringing on their patents and therefore cannot practice our technology as claimed under our patents and patent applications. Competitors may also contest our patents and patent application, if issued, by showing the patent examiner that the invention was not original, was not novel or was obvious. In litigation, a competitor could claim that our patents and patent application are not valid for a number of reasons. If a court agrees, we would lose that patents or patent application. As a company, we have no meaningful experience with competitors interfering with our patents or patent applications.
	2.	Because of the time, money and effort involved in obtaining and enforcing patents, our management may spend less time and resources on developing potential drug compounds than they otherwise would, which could increase our operating expenses and delay product programs.
	3.	Receipt of a patent may not provide much practical protection. If we receive a patent with a narrow scope, then it will be easier for competitors to design products that do not infringe on our patent.
	4.	In addition, competitors also seek patent protection for their inventions. Due to the number of patents in our field, we cannot be certain that we do not infringe on existing patents or that we will not infringe on patents granted in the future. If a patent holder believes our potential drug compound infringes on their patent, the patent holder may sue us even if we have received patent protection for our technology. If someone else claims we infringe on their patent, we would face a number of issues which could cause a slow down or cessation of our research and development, including the following:
		(a)	Defending a lawsuit takes significant time and can be very expensive.
		(b)	If the court decides that our potential drug compound infringes on the competitor’s patent, we may have to pay substantial damages for past infringement.
		(c)	The court may prohibit us from selling or licensing the potential drug compound unless the patent holder licenses the patent to us. The patent holder is not required to grant us a license. If a license is available, we may have to pay substantial royalties or grant cross licenses to our patents.
		(d)	Redesigning our potential drug compounds so that they do not infringe on other patents may not be possible or could require substantial funds and time.

It is also unclear whether our trade secrets are adequately protected. While we use reasonable efforts to protect our trade secrets, our employees or consultants may unintentionally or willfully disclose our information to competitors. Enforcing a claim that someone else illegally obtained and is using our trade secrets, like patent litigation, is expensive and time consuming, and the outcome is unpredictable. In addition, courts outside the United States are sometimes less willing to protect trade secrets. Our competitors may independently develop equivalent knowledge, methods and know-how.

We may also support and collaborate in research conducted by government organizations, hospitals, universities or other educational institutions. These research partners may be unwilling to grant us any exclusive rights to technology or products derived from these collaborations prior to entering into the relationship.

If we do not obtain required licenses or rights, we could encounter delays in our product development efforts while we attempt to design around other patents or even be prohibited from developing, manufacturing or selling potential drug compounds requiring these licenses. There is also a risk that disputes may arise as to the rights to technology or potential drug compounds developed in collaboration with other parties.

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We will incur increased costs as a result of recently enacted and proposed changes in laws and regulations and we cannot predict the impact of any future changes in law.

We face burdens relating to the recent trend toward stricter corporate governance and financial reporting standards. New legislation or regulations such as Section 404 of the Sarbanes-Oxley Act of 2002 follow the trend of imposing stricter corporate governance and financial reporting standards have led to an increase in our costs of compliance including increases in consulting, auditing and legal fees. Any new rules could make it more difficult or more costly for us to obtain certain types of insurance, including directors’ and officers’ liability insurance, and we may be forced to accept reduced policy limits and coverage or incur substantially higher costs to obtain the same or similar coverage. The impact of these events could also make it more difficult for us to attract and retain qualified persons to serve on our board of directors, our board committees or as executive officers. A failure to comply with these new laws and regulations may impact market perception of our financial condition and could materially harm our business. Additionally, it is unclear what additional laws or regulations may develop, and we cannot predict the ultimate impact of any future changes in law.

Risks Related to our Common Stock

A decline in the price of our common stock could affect our ability to raise further working capital and adversely impact our operations and would severely dilute existing or future investors if we were to raise funds at lower prices.

A prolonged decline in the price of our common stock could result in a reduction in the liquidity of our common stock and a reduction in our ability to raise capital. Because our operations have been financed through the sale of equity securities, a decline in the price of our common stock could be especially detrimental to our liquidity and our continued operations. Any reduction in our ability to raise equity capital in the future would force us to reallocate funds from other planned uses and would have a significant negative effect on our business plans and operations, including our ability to develop new products and continue our current operations. If the stock price declines, there can be no assurance that we can raise additional capital or generate funds from operations sufficient to meet our obligations. We believe the following factors could cause the market price of our common stock to continue to fluctuate widely and could cause our common stock to trade at a price below the price at which you purchase your shares of common stock:

• actual or anticipated variations in our quarterly operating results;

• announcements of new services, products, acquisitions or strategic relationships by us or our competitors;

• changes in accounting treatments or principles;

• changes in earnings estimates by securities analysts and in analyst recommendations; and

• general political, economic, regulatory and market conditions.

The market price for our common stock may also be affected by our ability to meet or exceed expectations of analysts or investors. Any failure to meet these expectations, even if minor, could materially adversely affect the market price of our common stock.

If we issue additional shares of common stock in the future, it will result in the dilution of our existing stockholders.

Our articles of incorporation authorize the issuance of 150,000,000 shares of common stock. Our board of directors has the authority to issue additional shares of common stock up to the authorized capital stated in the articles of incorporation. Our board of directors may choose to issue some or all of such shares of common stock to acquire one or more businesses or to provide additional financing in the future. The issuance of any such shares of common stock will result in a reduction of the book value or market price of the outstanding shares of our common stock. If we do issue any such additional shares of common stock, such issuance also will cause a reduction in the proportionate ownership and voting power of all other stockholders. Further, any such issuance may result in a change of control of our corporation.

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Trading on the OTC Bulletin Board may be volatile and sporadic, which could depress the market price of our common stock and make it difficult for our stockholders to resell their shares.

There is currently a limited market for our common stock. Our common stock is quoted on the OTC Bulletin Board service of the Financial Industry Regulatory Authority. Trading in stock quoted on the OTC Bulletin Board is often thin and characterized by wide fluctuations in trading prices, due to many factors that may have little to do with our operations or business prospects. This volatility could depress the market price of our common stock for reasons unrelated to operating performance. Moreover, the OTC Bulletin Board is not a stock exchange, and trading of securities on the OTC Bulletin Board is often more sporadic than the trading of securities listed on a quotation system like NASDAQ. There is no assurance that a sufficient market will develop in the stock, in which case it could be difficult for our stockholders to resell their stock.

Our stock is a penny stock. Trading of our stock may be restricted by the Securities and Exchange Commission’s penny stock regulations which may limit a stockholder’s ability to buy and sell our stock.

Our stock is a penny stock. The Securities and Exchange Commission has adopted Rule 15g-9 which generally defines “penny stock” to be any equity security that has a market price (as defined) less than $5.00 per share or an exercise price of less than $5.00 per share, subject to certain exceptions. Our securities are covered by the penny stock rules, which impose additional sales practice requirements on broker-dealers who sell to persons other than established customers and “accredited investors”. The term “accredited investor” refers generally to institutions with assets in excess of $5,000,000 or individuals with a net worth in excess of $1,000,000 or annual income exceeding $200,000 or $300,000 jointly with their spouse. The penny stock rules require a broker-dealer, prior to a transaction in a penny stock not otherwise exempt from the rules, to deliver a standardized risk disclosure document in a form prepared by the Securities and Exchange Commission which provides information about penny stocks and the nature and level of risks in the penny stock market. The broker-dealer also must provide the customer with current bid and offer quotations for the penny stock, the compensation of the broker-dealer and its salesperson in the transaction and monthly account statements showing the market value of each penny stock held in the customer’s account. The bid and offer quotations, and the broker-dealer and salesperson compensation information, must be given to the customer orally or in writing prior to effecting the transaction and must be given to the customer in writing before or with the customer’s confirmation. In addition, the penny stock rules require that prior to a transaction in a penny stock not otherwise exempt from these rules, the broker-dealer must make a special written determination that the penny stock is a suitable investment for the purchaser and receive the purchaser’s written agreement to the transaction. These disclosure requirements may have the effect of reducing the level of trading activity in the secondary market for the stock that is subject to these penny stock rules. Consequently, these penny stock rules may affect the ability of broker-dealers to trade our securities. We believe that the penny stock rules discourage investor interest in and limit the marketability of our common stock.

The Financial Industry Regulatory Authority sales practice requirements may also limit a stockholder’s ability to buy and sell our stock.

In addition to the “penny stock” rules described above, the Financial Industry Regulatory Authority or FINRA has adopted rules that require that in recommending an investment to a customer, a broker-dealer must have reasonable grounds for believing that the investment is suitable for that customer. Prior to recommending speculative low-priced securities to their non-institutional customers, broker-dealers must make reasonable efforts to obtain information about the customer’s financial status, tax status, investment objectives and other information. Under interpretations of these rules, FINRA believes that there is a high probability that speculative low-priced securities will not be suitable for at least some customers. The FINRA requirements make it more difficult for broker-dealers to recommend that their customers buy our common stock, which may limit your ability to buy and sell our stock and have an adverse effect on the market for shares of our common stock.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.

On October 2, 2009 we issued an aggregate of 266,666 units of our securities at a purchase price of $2.25 per unit to two offshore investors. Each unit consists of one share of common stock in the capital of our company and 1.125 common share purchase warrants. One full warrant entitles the holder to purchase one additional share of common stock at a price of $2.25 per warrant share for a period of two years. We issued these units to two non-U.S. persons

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(as that term is defined in Regulation S of the Securities Act of 1933, as amended) in an offshore transaction in which we relied on the registration exemption provided for in Regulation S of the Securities Act of 1933, as amended.

Item 3. Defaults upon Senior Securities.

Pursuant to a termination agreement we have issued one non-interest bearing promissory note to Panos Kontzalis, a former officer of our company, in the amount of $200,000. We have repaid $100,000 and, as at December 31, 2009 and September 30, 2009, we were in default of the payment terms for the remaining $100,000 balance owing. Subsequent to December 31, 2009, we and Mr. Kontzalis agreed to settle the outstanding amount owed by issuing 49,505 shares of our common stock.

Item 4. Submission of Matters to a Vote of Security Holders.

None.

Item 5. Other Information.

Pursuant to a termination agreement we have issued one non-interest bearing promissory note to Panos Kontzalis, a former officer of our company, in the amount of $200,000. We have repaid $100,000 and, as at December 31, 2009 and September 30, 2009, we were in default of the payment terms for the remaining $100,000 balance owing. On February 8, 2010, we agreed to settle the outstanding amount owed by issuing 49,505 shares of our common stock. We will issue these shares to a non-U.S. person (as that term is defined in Regulation S of the Securities Act of 1933, as amended) in an offshore transaction relying on the registration exemption provided for in Regulation S of the Securities Act of 1933, as amended.

On May 5, 2009, we issued Stonehedge Limited a promissory note with a principal amount of $150,000 that matured on December 31, 2009 bearing an interest rate of 8%. On January 1, 2010, this promissory note was replaced by another promissory note with a principal amount of $157,890 maturing on December 31, 2010 bearing interest rate of 8%.

Item 6. Exhibits.

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* Filed herewith.

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

ANAVEX LIFE SCIENCES CORP.

By:

/s/ Dr. Herve de Kergrohen                              
Dr. Herve de Kergrohen
Chief Executive Officer and Director
(Principal Executive Officer)
Date: February 22, 2010

By:

/s/ Harvey Lalach                                              
Harvey Lalach
President, Chief Financial Officer, Secretary and Director
(Principal Financial Officer and Principal Accounting Officer)
Date: February 22, 2010

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