Attached files

file filename
EX-23.1 - EX-23.1 - IsoPlexis Corpexhibit231-sx1.htm
EX-21.1 - EX-21.1 - IsoPlexis Corpexhibit211-sx1.htm
EX-10.9 - EX-10.9 - IsoPlexis Corpexhibit109-sx1.htm
EX-10.8 - EX-10.8 - IsoPlexis Corpexhibit108-sx1.htm
EX-10.7 - EX-10.7 - IsoPlexis Corpexhibit107-sx1.htm
EX-10.6 - EX-10.6 - IsoPlexis Corpexhibit106-sx1.htm
EX-10.5 - EX-10.5 - IsoPlexis Corpexhibit105-sx1.htm
EX-10.4 - EX-10.4 - IsoPlexis Corpexhibit104-sx1.htm
EX-10.3 - EX-10.3 - IsoPlexis Corpexhibit103-sx1.htm
EX-10.2 - EX-10.2 - IsoPlexis Corpexhibit102-sx1.htm
EX-10.1 - EX-10.1 - IsoPlexis Corpexhibit101-sx1.htm
EX-4.3 - EX-4.3 - IsoPlexis Corpexhibit43-sx1.htm
S-1 - S-1 - IsoPlexis Corpisoplexis-sx1.htm
Exhibit 5.1

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         , 2021

IsoPlexis Corporation
Registration Statement on Form S-1

Ladies and Gentlemen:
    We have acted as counsel for IsoPlexis Corporation, a Delaware corporation (the “Company”), in connection with the registration statement on Form S-1, as amended (Registration No. 333-         ) (the “Registration Statement”), filed with the Securities and Exchange Commission (the “Commission”) under the Securities Act of 1933, as amended (the “Securities Act”), with respect to the registration of shares of common stock, par value $0.001 per share, of the Company (the “Shares”), and, if the over-allotment option is exercised, the offer and sale by the Company of additional shares (the “Additional Shares”) to the underwriters (the “Underwriters”) pursuant to the terms of the underwriting agreement (the “Underwriting Agreement”) to be executed by the Company and Morgan Stanley & Co. LLC, Cowen and Company, LLC, Evercore Group, L.L.C. and SVB Leerink LLC, as Representatives of the Underwriters.
    In that connection, we have examined originals, or copies certified or otherwise identified to our satisfaction, of such documents, corporate records and other instruments as we have deemed necessary or appropriate for the purposes of this opinion, including, without limitation: (a) the Eighth Amended and Restated Certificate of Incorporation of the Company; (b) the Amended and Restated By-laws of the Company; and (c) certain resolutions adopted by the Board of Directors of the Company.
    In rendering our opinion, we have assumed the genuineness of all signatures, the legal capacity of all natural persons, the authenticity of all documents submitted to us as originals, the conformity to original documents of all documents submitted to us as certified, conformed or photostatic copies and the authenticity of the originals of such     



latter documents. As to all questions of fact material to this opinion that have not been independently established, we have relied upon certificates or comparable documents of officers and representatives of the Company.

    Based on the foregoing and in reliance thereon, we are of opinion that the Shares and the Additional Shares have been duly and validly authorized and, when issued and delivered by the Company and paid for by the Underwriters pursuant to the Underwriting Agreement, will be validly issued, fully paid and non-assessable.

    We are admitted to practice in the State of New York, and we express no opinion as to matters governed by any laws other than the laws of the State of New York, the General Corporation Law of the State of Delaware and the Federal laws of the United States of America. The reference and limitation to “General Corporation Law of the State of Delaware” includes the statutory provisions and all applicable provisions of the Delaware Constitution and reported judicial decisions interpreting these laws.

    We hereby consent to the filing of this opinion with the Commission as Exhibit 5.1 to the Registration Statement. We also consent to the reference to our firm under the caption “Legal Matters” in the Registration Statement. In giving this consent, we do not thereby admit that we are included in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations of the Commission.

Very truly yours,

IsoPlexis Corporation
35 NE Industrial Rd
Branford, CT 06405

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