UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of The Securities Exchange Act of 1934

Date of Report (Date of Earliest Event Reported): March 25, 2016

Inotek Pharmaceuticals Corporation

(Exact name of registrant as specified in its charter)

Registrant’s telephone number, including area code (781) 676-2100

Not Applicable

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Inotek Pharmaceuticals Corporation (the “Company”) has established the record date for its 2016 annual meeting of stockholders (the “2016 Annual Meeting”). The Company’s stockholders of record at the close of business on April 28, 2016 will be entitled to notice of the 2016 Annual Meeting and to vote upon matters considered at the 2016 Annual Meeting. The 2016 Annual Meeting will be held at a time and place to be included in the notice of the 2016 Annual Meeting which will accompany the Company’s proxy materials.

The information in this Report on Form 8-K is intended to be furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such filing.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.