I, Ken Reali, hereby certify pursuant to
Rule 13a-14(b) or Rule 15d-14(b) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) and 18 U.S.C.
Section 1350, that the Quarterly Report on Form 10-Q of Baxano Surgical, Inc. (the “Company”) for the quarterly
period ended June 30, 2014 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the
Exchange Act and that the information contained in the Report fairly presents, in all material respects, the financial condition
and results of operations of the Company.
|Date: August 14, 2014
||/s/ Ken Reali|
||President and Chief Executive Officer|
||(Principal Executive Officer)|
This certification accompanies the Report
pursuant to Rule 13a-14(b) or Rule 15d-14(b) under the Exchange Act and 18 U.S.C. Section 1350 and shall not be deemed filed
by the Company for purposes of Section 18 of the Exchange Act, and shall not be incorporated by reference into any filing
of the Company under the Securities Act of 1933, as amended, or the Exchange Act, whether made before or after the date of this
Report, irrespective of any general incorporation language contained in such filing.
A signed original of this certification
has been provided to the Company and will be retained by the Company and furnished to the Securities and Exchange Commission or
its staff upon request.