Exhibit 31.1

CERTIFICATION
PURSUANT TO RULE 13a-14(a)

I, Robert L. Chioini, certify that:

1.                                      I have reviewed this annual report on Form 10-K/A of Rockwell Medical, Inc.; and

2.                                      Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.