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ACADIA Pharmaceuticals Inc. ("ACADIA") announced that Jeffrey Cummings, M.D., Sc.D., Director of Cleveland Clinic Lou Ruvo Center for Brain Health, presented detailed results on Wednesday, March 20, 2013, from ACADIA's pivotal Phase III -020 Study with pimavanserin in patients with Parkinson's disease psychosis at the Emerging Science session of the 65th American Academy of Neurology ("AAN") Annual Meeting. Pimavanserin met the primary endpoint in the -020 Study by demonstrating highly significant antipsychotic efficacy on the SAPS-PD scale (p=0.001), which consists of nine items from the hallucinations and delusions domains of the Scale for the Assessment of Positive Symptoms ("SAPS"). Pimavanserin also met the key secondary endpoint of the study for motoric tolerability as measured using Parts II and III of the Unified Parkinson's Disease Rating Scale, or UPDRS. Dr. Cummings presented previously unreported data from the -020 Study showing highly significant improvements in all secondary efficacy measures, including the Clinical Global Impression Severity ("CGI-S") scale (p
ACADIA Pharmaceuticals Inc. |
By: | /s/ Glenn F. Baity |
Name: Glenn F. Baity | |
Title: Vice President & General Counsel |