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                                                                    EXHIBIT 32.1

                  CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER
            PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

Pursuant to 18 U.S.C. Section 1350, as created by Section 906 of the
Sarbanes-Oxley Act of 2002, the undersigned officer of Upstream Biosciences Inc.
(the "Company") hereby certifies, to such officer's knowledge, that:

     (1)  the Annual Report on Form 10-K of the Company for the year ended
          September 30, 2012 (the "Report") fully complies with the requirements
          of Section 13(a) or Section 15(d), as applicable, of the Securities
          Exchange Act of 1934, as amended; and

     (2)  the information contained in the Report fairly presents, in all
          material respects, the financial condition and results of operations
          of the Company.


Dated: December 31, 2012    By: /s/ Charles El-Moussa
                               -------------------------------------------------
                               Charles El-Moussa
                               Chief Executive Officer, Chief Financial
                               Officer, President, Secretary, Treasurer and
                               Director
                               (Principal Executive Officer, Principal Financial
                               Officer and Principal Accounting Officer)

A signed original of this written statement required by Section 906, or other
document authenticating, acknowledging, or otherwise adopting the signature that
appears in typed form within the electronic version of this written statement
required by Section 906, has been provided to Upstream Biosciences Inc. and will
be retained by Upstream Biosciences Inc. and furnished to the Securities and
Exchange Commission or its staff upon request