Exhibit 99.1

Letter of Intent

#C4CT Concussion Awareness Conference

This Letter of Intent (“LOI”) is made as of this 30^th day of December 2012 by and between Amarantus BioScience, Inc. (OTCQB: AMBS) (hereinafter, “AMBS”), Toi Cook Management Group, LLC (“TCMG”)and Brewer Sports International, LLC (“Brewer”). Each of AMBS, TCMG and Brewer may also be referred to herein each as a “Party,” and collectively as the “Parties.”

Brewer is a multi-faceted sports advisory firm within ‘The Brewer Group Companies.’ Brewer focuses on the businesses of sports, wellness and media. Brewer provides services that include sports lending, corporate advisory consulting and identifying media opportunities for professional athletes, sports agencies, sports leagues and player associations. Where appropriate, Brewer may also engage with international organizations and governments, with whom BSI maintains relationships, and support and endorse certain philanthropic causes. Brewer is committed to contributing to advances in the diagnosis and treatment of sport-related concussions, and has prior hereto co-founded with AMBS the ‘Coalition for Concussion Treatment’ (“#C4CT”), an awareness movement seeking to inform the public of the need to develop effective diagnostic tools and treatments for human brain injuries and cognitive disorders.

AMBS is a development-stage biotechnology company founded in January 2008. AMBS develops therapeutic proteins to diagnose and/or treat human medical conditions such as Parkinson’s disease and Traumatic Brain Injury. The proprietary therapeutic protein developed by AMBS chief scientist John W. Commissiong, PhD, is known as Mesencephalic-Astrocyte-derived Neurotrophic Factor (“MANF”). AMBS is currently developing MANF-based products as possible treatments for human brain injuries and disorders. As a Founding Member of the #C4CT along with Brewer, AMBS desires to continue to find outlets to promote the cause of fighting human brain injuries and disorders.

TCMG is a consulting firm specializing in the creation of alliances between businesses and professional sports leagues, professional athletes and/or professional entertainers with the purpose of advancing business opportunities and creating awareness for such opportunities.

This LOI therefore reflects the culmination of prior discussions and information exchanged to date between the Parties regarding their contemplated collaboration to coordinate and co-host a #C4CT Concussion Awareness Conference (the “Conference,” and the Parties’ collaboration relating to the Conference being referred to as the “Transaction”) along with certain other affiliates or associates, which include nationally recognized current and former players in the National Football League (“NFL”).

Except as otherwise specifically set forth herein (and any such obligations being typed in italics), this LOI is executed for discussion purposes only and in order to allow AMBS and its Board to meet with its current and future sponsors of the #C4CT initiative and planned Conference. This LOI contemplates that the Parties will immediately complete such due diligence as may be reasonably necessary and thereafter execute “Definitive Agreements” covering all aspects of the Transaction no later than January 31, 2013 (unless extended in writing by the Parties). Further, this LOI is intended to confirm the Parties’ mutual understanding of the basic conceptual framework of the Transaction as set forth in the “Core Contemplated Terms” section below, as well as the Parties’ mutual willingness and intention to proceed in good faith to work towards execution of the Definitive Agreements according to this framework.

Following execution of this LOI, the Parties agree to immediately commence good faith negotiation and drafting of the Definitive Agreements. Additionally, for the purpose of advancing the Transaction, the Parties agrees to use their best efforts to make available any information required by the other in connection with such Party’s due diligence efforts.

The Agreements shall contain all such terms and conditions as are customary and/or desirable in connection with transactions of the nature of the Transaction contemplated herein.

Each Party represents and warrants to the other that:

Except as and to the extent required by law, each Party agrees that it shall not disclose or use, and it shall cause its representatives not to disclose or use, the Confidential Information (as defined below) of the other Party furnished, or to be furnished, by either Party or its representatives to the other Party or its representatives in connection with this LOI at any time or in any manner, other than in connection with its evaluation of the Transaction. “Confidential Information” means any information of a non-public nature about one Party provided by that Party to the other Party hereunder. If this LOI is terminated, each Party shall promptly return to the other Party such other Party’s Confidential Information. Notwithstanding anything to the contrary in this LOI, this paragraph shall be binding on the Parties and shall survive termination of this LOI.

This LOI may be terminated: (i) at any time by mutual written consent of the Parties; (ii) automatically, if the Definitive Agreements are not executed by January 31, 2013 (as may be extended); and (iii) at any time by either Party, if either shall determine in its sole discretion that the results of its due diligence investigation are not satisfactory in any respect.

Each Party will pay its own legal, accounting and other expenses incident to the negotiation, execution and delivery of this LOI and the Definitive Agreements.

CORE CONTEMPLATED TERMS

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THE ABOVE LETTER OF INTENT IS ACKNOWLEDGED, AGREED AND ACCEPTED by the below Parties on the date first above written.