Exhibit 5.1

		Pacific Northwest Office 805 SW Broadway, Suite 2440 Portland, Oregon 97205 Telephone: 503/419-3000 ~ Facsimile: 503/419-3001 www.white-summers.com

September 4, 2012

Sarepta Therapeutics, Inc

3450 Monte Villa Parkway, Suite 101

Bothell, WA 98021

Re: Registration Statement on Form S-3.

Ladies and Gentlemen:

We have acted as special legal counsel to Sarepta Therapeutics, Inc., an Oregon corporation (the “Company”), in connection with the registration of the offer and sale of that number of shares of the Company’s common stock, $0.0001 par value per share having an aggregate offering price of up to $40,000,000 of the Company’s common stock, $0.0001 par value per share, (the “Shares”) pursuant to a registration statement on Form S-3 under the Securities Act of 1933, as amended (the “Act”), filed with the Securities and Exchange Commission (the “Commission”) on March 21, 2012 (Registration No. 333-180258) (as so filed and as amended, the “Registration Statement”), the base prospectus filed as part of such Registration, (the “Base Prospectus”), a prospectus supplement dated September 4, 2012 filed with the Commission pursuant to Rule 424 (b) under the Act (together with the Base Prospectus, the “Prospectus”)

The offering and sale of the Shares are being made in connection with that certain at-the-market equity offering sales agreement dated September 4, 2012, between the Company and Citadel Securities LLC as the sales agent or principal (the “Sales Agreement”).

We have examined copies of the Sales Agreement, the Registration Statement and the Prospectus. We have also examined instruments, documents and records which we deemed relevant and necessary for the basis of our opinion hereinafter expressed.

In such examination, we have assumed (i) the authenticity of original documents and the genuineness of all signatures, (ii) the conformity to the originals of all documents submitted to us as copies, and (iii) the truth, accuracy, and completeness of the information, representations and warranties contained in the records, documents, instruments and certificates we have reviewed.

Based on and subject to the foregoing, we are of the opinion that:

We express no opinion as to the laws of any other jurisdiction other than the federal laws of the United States of America and the Oregon Business Corporation Act.

We consent to your filing this opinion as an exhibit to the Company’s Current Report on Form 8-K, dated September 4, 2012, and to the reference to our firm in the Prospectus under the heading “Legal Matters.”