Exhibit 99.1

RADIATION THERAPY SERVICES HOLDINGS, INC.

RADIATION THERAPY SERVICES REPORTS SECOND QUARTER 2012

FINANCIAL RESULTS

Second Quarter 2012 Financial Highlights:

·                  Total company revenues increased 11.1% to $180.3 million

·                  Domestic same practice treatments per day increased 4.1%

·                  Medical Developers’ international cases increased 13.6%

·                  Pro Forma Adjusted EBITDA of $28.1 million

Recent Business Highlights:

·                  In May 2012, issued $350.0 million in aggregate principal amount of new 8.875% senior notes due 2017 and entered into new revolving credit facility, allowing for up to $140 million in borrowings

·                  Radiation Therapy focused on providing comments to CMS regarding the Preliminary Physician Fee Schedule for 2013

·                  In August 2012, entered into national contract with major commercial payer to provide radiation therapy services under innovative case rate payment methodology; creates greater alignment and opportunities for strategic growth in several key markets

FORT MYERS, FL, August 8, 2012 — Radiation Therapy Services Holdings, Inc (“Radiation Therapy” or “the Company”), a leading operator of radiation therapy centers, today announced financial results for the second quarter ended June 30, 2012.

Dr. Daniel Dosoretz, President and Chief Executive Officer, said, “We are pleased with our 4.1% increase in domestic same practice treatments per day as it reflects our continued progress with our integrated cancer care strategy and physician liaison program. We strongly believe that these efforts will serve to enhance Radiation Therapy’s leading position as a provider of advanced cancer care, and ensure that our patients continue to receive the highest level of care. As expected, we did experience some EBITDA margin compression during the quarter primarily as

a result of our execution of the integrated cancer care strategy, as well as lower Medicare reimbursement.”

“On July 6, CMS published its preliminary 2013 Physician Fee Schedule, which included potential cuts for radiation oncology at freestanding centers.  If enacted, we believe the severity of the cuts would result in center closures, particularly in rural areas, thereby limiting important access to treatment for patients with cancer of all diagnoses.  Along with other providers and advocacy groups, our number one priority is to work with CMS, Congress and the Obama Administration to help them to understand the true cost associated with providing appropriate integrated cancer care, and providing them the information necessary to make informed decisions regarding appropriate reimbursement levels. We are hopeful that our efforts will result in these significant cuts being mitigated as part of the Final Rule in late 2012. Concurrently, we are developing contingency plans to offset the impact of possible cuts in 2013,” concluded Dr. Dosoretz.

Recent Developments

In May 2012, Radiation Therapy issued $350.0 million in aggregate principal amount of its new 8.875% senior secured second lien notes due 2017 (the “Notes”).  Net proceeds from the sale of the Notes were used to repay Radiation Therapy’s existing senior secured revolving credit facility and the Term Loan B portion of its senior secured credit facilities, to pay fees and expenses related to the notes offering and for general corporate purposes.  In connection with the Notes offering, Radiation Therapy also entered into a new 4.5 year $140 million revolving credit facility.  As of August 8, 2012, there were no borrowings under the revolving credit facility.

On July 6, 2012, the Centers for Medicare and Medicaid Services (CMS) published the preliminary 2013 Physician Fee Schedule, which included significant proposed cuts which particularly would affect freestanding radiation therapy centers.  The Company, along with other providers and advocacy groups, will be providing comments to CMS and legislators during the 60-day comment period.

Effective August 1, 2012, Radiation Therapy entered into a national contract with a major commercial payer to provide radiation therapy services under an innovative case rate payment methodology. In line with the efforts of leading healthcare policymakers to fight waste, recognize quality care, encourage coordination across providers, and reduce health care costs, this innovative case rate fee restructuring for radiation oncology provides a single payment to cover the group of procedures performed during a particular course of care.

Second Quarter 2012 Results

Total revenues for the second quarter of 2012 were $180.3 million, an increase of 11.1% compared to $162.3 million in revenues in the same quarter of 2011. The increase in revenue was principally due to the benefit of acquired integrated cancer care (ICC) practices, the impact of strategic tuck-in acquisitions made in California, North Carolina, Florida and Argentina, the

value added services agreement with the North Broward Hospital District and organic growth from Medical Developers, the Company’s Latin American operations.

Compared to the second quarter of 2011, domestic same practice treatments per day increased 4.1% in the second quarter of 2012, reflecting continued volume improvements, increased referrals from the Company’s physician liaison program and integrated cancer care model, and the impact of the North Broward hospital value added services agreement which is ahead of expectations. Domestic same practice freestanding revenue per treatment decreased 3.5% from the second quarter of 2011, due to reductions in the reimbursement rates announced in the CMS 2012 Physician Fee Schedule, partially offset by improved managed care pricing.

Total RVUs per day at same practice domestic freestanding centers, excluding the impact of the Las Vegas capitated contract, decreased 4.8% in the second quarter versus the same period of the prior year principally due to reductions in reimbursement rates included in the CMS 2012 Physician Fee Schedule.

Adjusted earnings before interest, taxes, depreciation, amortization, stock-based compensation and other non-cash and pro forma items (“Pro Forma Adjusted EBITDA”) in the second quarter of 2012 was $28.1 million, or 15.6% of total pro forma revenues, compared to $30.0 million, or 18.5% of total pro forma revenues, in the second quarter of 2011. Pro Forma Adjusted EBITDA margins declined in the quarter versus the prior year period primarily due to reductions in Medicare reimbursement rates, growth in integrated cancer care practices, and investments made in key personnel.  A reconciliation of net loss attributable to Radiation Therapy Services Holdings, Inc., determined in accordance with generally accepted accounting principles to Pro Forma Adjusted EBITDA and total revenues, determined in accordance with generally accepted accounting principles, to total pro forma revenues for the quarters ended June 30, 2012 and 2011 is included in the attached supplemental information.

Income tax expense in the second quarter of 2012 was $1.4 million, compared to income tax expense of $3.3 million in the second quarter of 2011.  The net loss for the second quarter of 2012 was $19.0 million, compared to a net loss of $4.8 million in the second quarter of 2011.

First Six Months of 2012 Results

Total revenues for the six months ended June 30, 2012 were $357.7 million, an increase of 12.2% compared to $318.8 million in revenues in the same period of 2011. The increase in revenue was principally due to the benefit of acquired integrated cancer care practices, the impact of strategic tuck-in acquisitions made in California, North Carolina, Florida and Argentina, the value added services agreement with the North Broward Hospital District and organic growth from Medical Developers.

Compared to the first six months of 2011, domestic same practice treatments per day increased 3.1% in the first six months of 2012, reflecting continued volume improvements, increased referrals from the Company’s physician liaison program and integrated cancer care model, and the impact of the North Broward value added services agreement which is ahead of expectations.  Domestic same practice therapy revenue per treatment decreased 3.0% from the first six months

of 2011, due to reductions in reimbursement rates announced in the CMS 2012 Physician Fee Schedule which were partially offset by improved managed care pricing.

Total RVUs per day at same practice domestic freestanding centers, excluding the impact of the Las Vegas capitated contract, decreased 5.1% in the first six months versus the same period of the prior year principally due to reductions in reimbursement rates included in the CMS 2012 Physician Fee Schedule.

Pro Forma Adjusted EBITDA in the first six months of 2012 was $57.6 million, or 15.8% of total pro forma revenues, compared to $62.0 million, or 18.8% of total pro forma revenues, in the first six months of 2011. Pro Forma Adjusted EBITDA margins declined in the period versus the prior year period primarily due to reductions in Medicare reimbursement rates, growth in integrated care practices and investments made in key personnel.  A reconciliation of net loss attributable to Radiation Therapy Services Holdings, Inc., determined in accordance with generally accepted accounting principles to Pro Forma Adjusted EBITDA and total revenues, determined in accordance with generally accepted accounting principles, to total pro forma revenues for the six-month periods ended June 30, 2012 and 2011 is included in the attached supplemental information.

Income tax expense in the first six months of 2012 was $1.5 million, compared to income tax expense of $5.8 million in the first six months of 2011.  The net loss for the first six months of 2012 was $27.4 million, compared to a net loss of $7.9 million in the first six months of 2011.

Conference Call

Management will host a conference call Thursday, August 9, 2012 at 11 a.m. ET to discuss financial results, other developments and business conditions. The dial-in numbers are (877) 407-0789 for domestic callers and (201) 689-8562 for international callers.  In addition, a telephonic replay of the call will be available until August 23, 2012.  The replay dial-in numbers are (877) 870-5176 for domestic callers and (858) 384-5517 for international callers.  Please use the conference ID number 397867 to access the replay.

A live webcast and webcast replay of the call will also be available from the Investor Relations section on the corporate web site at www.rtsx.com.

About Radiation Therapy Services Holdings, Inc.

Radiation Therapy is a leading provider of advanced radiation therapy and other services to cancer patients in the United States and Latin America.  The Company offers a comprehensive range of radiation treatment alternatives, focused on delivering academic quality, cost-effective patient care in a personal and convenient setting. In total, the Company operates 126 treatment centers, including 95 centers located in 15 U.S. states, strategically clustered in 28 local markets. The Company also operates 30 centers located in six countries in Latin America and 1 center located in India.  The Company holds market leading positions in most of its domestic local markets and abroad.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Act of 1934, as amended.  Statements preceded by, followed by or that otherwise include the words “believes”, “expects”, “anticipates”, “intends”, “projects”, “estimates”, “plans”, “may increase”, “forecast” and similar expressions or future or conditional verbs such as “will”, “should”, “would”, “may” and “could” are generally forward-looking in nature and not historical facts. Forward-looking statements are based on management’s current expectations or beliefs about the Company’s future plans, expectations and objectives, including, but not limited to, the Company’s expected financial results and estimates for 2012 and beyond.  These forward-looking statements are not historical facts and are subject to risks and uncertainties that could cause the actual results to differ materially from those projected in these forward-looking statements including, but not limited to reductions in Medicare reimbursement, healthcare reform, decreases in payments by managed care organizations and other commercial payers and other risk factors that may be described from time to time in the Company’s filings with the Securities and Exchange Commission.  Readers of this release are cautioned not to place undue reliance on forward-looking statements contained herein, which speak only as of the date stated, or if no date is stated, as of the date of this press release. The Company undertakes no obligation to publicly update or revise the forward-looking statements contained herein to reflect changed events or circumstances after the date of this release, unless required by law.

Financial Tables on Following Pages

RADIATION THERAPY SERVICES HOLDINGS, INC.

CONDENSED CONSOLIDATED BALANCE SHEETS

(in thousands, except share and per share amounts)

RADIATION THERAPY SERVICES HOLDINGS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS

(in thousands)

(unaudited)

RADIATION THERAPY SERVICES HOLDINGS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(in thousands)

(unaudited)

RADIATION THERAPY SERVICES HOLDINGS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(in thousands)

(unaudited)

RADIATION THERAPY SERVICES HOLDINGS, INC.

Supplemental Financial Information (Unaudited)

Reconciliation of Total Pro-forma Revenue and Pro-forma Adjusted EBITDA to Net Loss Attributable

to Radiation Therapy Services Holdings, Inc. Shareholder

(1) Pro-forma Adjusted EBITDA is defined as income (loss) before interest expense (net of interest income), income taxes, depreciation and amortization, foreign currency derivative contract loss, gain on fair value adjustment of previously held equity investment, early extinguishment of debt, management fees from our sponsor, non-cash expenses including costs relating to stock compensation, amortization of straigh-line rent and amortization of capital expenditures relating to repairs and maintenance, sale-lease back adjustments, acquisition-related costs, other expenses including loss on sale of assets, severance payments related to termination of employee staff reductions, tail premiums on termed physicians, and franchise taxes, litigation settlements with physicians, costs associated with the provision for income taxes, costs associated with tradename and rebranding initiatives, expenses associated with idle / closed radiation therapy treatment facilities and pro-forma full period effect of acquisition EBITDA.

(a) Pro-forma amounts related to adjustments to total revenues and Pro-forma Adjusted EBITDA to reflect the full period effect of our acquisitions completed during 2011 and 2012.  The adjustments reflect the impact to our total revenues and Pro-forma Adjusted EBITDA as if the acquisitions had occurred at the beginning of the year.

(b) Management fees are fees paid to our sponsor, Vestar Capital Partners.

(c) Non-cash expenses including costs relating to stock compensation, amortization of straight-line rent and amortization of capital expenditures relating to warranty arrangements amortized to repairs and maintenance.

(d) Sale-lease back adjustments relates to the adjustment of benefit derived from the classification of operating leases as finance obiligations reflecting a reclassification of interest expense and depreciation and amortization expense as rent expense.

(e) Acquisition related costs associated with the adoption of ASC 805, Business Combinations, requiring prior capitalized costs be expensed, including professional fees and due diligence costs relating to the acquisition of physician practices.

(f) Other expenses include loss on sale of assets, severance payments related to termination of employee staff reductions, tail premiums paid on terminated physicians and franchise taxes.

(g) Litigation settlement relates to costs associated with the termination of physicians during 2011 and 2012.

(h) Expenses related to the costs associated with process improvements in the provision for income taxes.

(i) Expeses related to the costs associated with the Company’s tradename and rebranding initiatives.

(j) Expenses associated with idle / closed radiation therapy treatment facilities.

We believe the Pro-forma Adjusted EBITDA provides useful information about our financial performance to investors, lenders, financial analysts and rating agencies since these groups have historically used EBITDA-related measures in the healthcare industry, along with other measures, to estimate the value of a company, to make informed investment decisions, to evaluate a company’s leverage capacity and its ability to meet its debt service requirements.  Pro-forma Adjusted EBITDA eliminates the uneven effect of non-cash depreciation of tangibles assets and amortization of intangible assets, much of which results from acquisitions accounted for under the purchase method of accounting.  Pro-forma Adjusted EBITDA is also used by us to measure individual performance for incentive compensation purposes and as an analytical indicator for purposes of allocating resources to our operating business and assessing their performance, both internally and relative to our peers, as well as to evaluate the performance of our operating management teams, and for purposes in the calculation of debt covenants and related disclosures.

Pro-forma Adjusted EBITDA is not intended as a substitute for net income (loss) attributable to Radiation Therapy Services Holdings, Inc. shareholder, operating cash flows or other cash flow data determined in accordance with accounting principles generally accepted in the United States. Due to varying methods of calculation, Pro-forma Adjusted EBITDA as presented may not be comparable to similarly titled measures of other companies.

RADIATION THERAPY SERVICES HOLDINGS, INC.

KEY OPERATING STATISTICS

(unaudited)

* Excludes the impact of the termination of a capitated contract in Las Vegas, Nevada

** includes full period operating statistics, including period prior to our acquisition on March 1, 2011

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