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                                                                    EXHIBIT 32.1

                  CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER
            PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

Pursuant to 18 U.S.C. Section 1350, as created by Section 906 of the
Sarbanes-Oxley Act of 2002, the undersigned officer of Upstream Biosciences Inc.
(the "Company") hereby certifies, to such officer's knowledge, that:

     (1)  the Quarterly Report on Form 10-Q (Amendment No. 1) of the Company for
          the three months ended December 31, 2011 (the "Report") fully complies
          with the requirements of Section 13(a) or Section 15(d), as
          applicable, of the Securities Exchange Act of 1934, as amended; and

     (2)  the information contained in the Report fairly presents, in all
          material respects, the financial condition and results of operations
          of the Company.


                                   By: /s/ Charles El-Moussa
                                       -----------------------------------------
                                       Charles El-Moussa
                                       Chief Executive Officer, Chief Financial
                                       Officer, President, Secretary, Treasurer
                                       and Director (Principal Executive
                                       Officer, Principal Financial Officer and
                                       Principal Accounting Officer)

Dated: May 29, 2012

A signed original of this written statement required by Section 906, or other
document authenticating, acknowledging, or otherwise adopting the signature that
appears in typed form within the electronic version of this written statement
required by Section 906, has been provided to Upstream Biosciences Inc. and will
be retained by Upstream Biosciences Inc. and furnished to the Securities and
Exchange Commission or its staff upon request.