PROTALIX BIOTHERAPEUTICS, INC.
In connection with the quarterly report of Protalix BioTherapeutics,
Inc. (the “Company”) on Form 10-Q for the period ended March 31, 2012 as filed with the Securities and Exchange Commission
(the “Report”), I, David Aviezer, President and Chief Executive Officer of the Company, hereby certify as of the date
hereof, solely for purposes of Title 18, Chapter 63, Section 1350 of the United States Code, that to the best of my knowledge:
(1) the Report fully complies with the requirements
of Section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934; and
(2) the information contained in the Report fairly
presents, in all material respects, the financial condition and results of operations of the Company at the dates and for the periods
This Certification has not
been, and shall not be deemed, “filed” with the Securities and Exchange Commission.
|Date: May 9, 2012|
|/s/ David Aviezer
David Aviezer, Ph.D.
President and Chief Executive Officer