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EXHIBIT 99.1

Complete Genomics Reports Fourth Quarter and Fiscal Year 2011 Results

MOUNTAIN VIEW, Calif., March 8, 2012 (GLOBE NEWSWIRE) -- Complete Genomics, Inc. (Nasdaq:GNOM), the whole human genome sequencing company, today announced financial results for the fourth quarter and fiscal year ended December 31, 2011.

Fiscal Year 2011 Results

  • We recognized revenue with respect to approximately 3,000 genomes, compared to approximately 800 genomes in 2010.
  • Revenue was $19.3 million, compared to $9.4 million in 2010.
  • Costs and operating expenses were $88.6 million, compared to $57.0 million in 2010.
  • Net loss was $72.3 million, compared to $57.7 million in 2010. The net loss for 2010 had included a $7.2 million non-cash expense resulting from an accounting adjustment to the market value of certain convertible equity securities.

"In 2011, we clearly demonstrated the value of our service, signing orders for approximately 8,000 genomes representing aggregate revenue potential of $39 million, and delivering data to approximately 90 customers," said Dr. Clifford Reid, chairman, president and CEO of Complete Genomics. "We entered 2012 with a strong order book of about 5,800 genomes, representing aggregate revenue potential of approximately $28 million."

Fourth Quarter 2011 Results

  • Revenue was $2.5 million, compared to $3.8 million in the fourth quarter of 2010.
  • Costs and operating expenses were $24.0 million, compared to $14.7 million in the fourth quarter of 2010.
  • Net loss was $22.3 million, compared to $10.3 million in the fourth quarter of 2010.

In the fourth quarter of 2011, we recorded $7.4 million in expenses related to costs of services, compared to $4.9 million for start-up production expenses in the fourth quarter of 2010. Research and development expenses were $8.3 million during the fourth quarter of 2011, compared to $5.6 million in the fourth quarter of 2010. Sales and marketing expenses were $4.3 million during the fourth quarter of 2011, compared to $2.0 million in the fourth quarter of 2010. General and administrative expenses were $4.0 million during the fourth quarter of 2011, compared to $2.2 million in the fourth quarter of 2010.

We ended 2011 with $83.1 million in cash, cash equivalents and short-term investments and $0.5 million in restricted cash. 

Highlights since Our Last Earnings Release

  • For the genomes sequenced during the fourth quarter, the median call rate was over 96% of the genome.
  • In February 2012, we announced that we had been selected to provide outsourced whole human genome sequencing services by Mayo Clinic's Center for Individualized Medicine.
  • At the Advances in Genome Biology and Technology conference in February 2012, we announced software partnership arrangements with DNAnexus, Golden Helix and Ingenuity. Offerings from these partners complement information supplied by Complete Genomics' sequencing service and can be used by researchers to accelerate the pace of biological discoveries. 
  • In February 2012, we announced the establishment of our Genomic Medicine Advisory Board (GMAB). The board, comprised of thought leaders in genomic medicine, will provide guidance on how we can best provide sequencing services to healthcare organizations and physicians.  

First Quarter 2012 Outlook

We expect to sequence and provide customers data for between 1,100 to 1,300 genomes in the first quarter of 2012. We expect to have capacity to process approximately 1,000 genomes per month by the end of the first quarter and have already received samples for over 2,000 genomes that we expect to sequence for customers in the second quarter of 2012.

Conference Call

We will host a conference call on March 8, 2012 at 1:30 p.m. PT to discuss our financial results for the fourth quarter of 2011. The conference dial-in numbers are US: (877) 844 - 6890 or International: (760) 298 - 5092 (Conference ID: 57935965). A live audio webcast of the call will also be available in the Investor Relations section of our website at http://ir.completegenomics.com/events.cfm.

An audio webcast replay of the conference call will be available in the Investor Relations section of our website approximately two hours after the call and for 30 days thereafter.

About Complete Genomics

Complete Genomics is the whole human genome sequencing company that has developed and commercialized an innovative DNA sequencing platform. The Complete Genomics Analysis Platform (CGA™ Platform) combines our proprietary human genome sequencing technology with our advanced informatics and data management software. Additional information can be found at www.completegenomics.com.

Forward Looking Statements

Certain statements in this press release, including statements relating to potential revenue from orders, backlog, future numbers of genomes to be sequenced and shipped, expected increases to our sequencing capacity are forward-looking statements that are subject to risks and uncertainties. Readers are cautioned that these forward-looking statements are based on management's current expectations, and actual results may differ materially from those projected. The following factors, without limitation, could cause actual results to differ materially from the forward-looking statements: our limited operating history, delays in production due to technical issues, any failure to complete orders in our backlog and recognize the associated revenue, the timing of sample arrivals from customers, the timing and extent of reductions in the price of our genomic sequencing service, any potential inability to increase yield and any potential problems maintaining relationships with our customers. More information on factors that could affect our financial results can be found in our Annual Report on Form 10-K for the fiscal year ended December 31, 2010 filed on March 30, 2011 and the subsequently filed Quarterly Reports on Form 10-Q, including those factors listed under the caption "Risk Factors". We disclaim any obligation to update information contained in these forward-looking statements, whether as a result of new information, future events or otherwise.

Complete Genomics, Inc.
Consolidated Statements of Operations
(in thousands, except share and per share amounts)
       
  Years ended December 31,
  2011 2010 2009
       
Revenue  $ 19,344  $ 9,389  $ 623
       
Costs and expenses:      
Cost of revenues  28,309 -- --
Start-up production costs --  19,895  5,033
Research and development  32,691  21,691  22,424
General and administrative  14,039  9,345  4,953
Sales and marketing  13,600  6,111  1,798
       
Total costs and expenses  88,639  57,042  34,208
       
Loss from operations  (69,295)  (47,653)  (33,585)
       
Interest expense  (2,732)  (2,827)  (3,465)
Interest and other income (expense), net  (321)  (7,207)  1,101
       
Net loss   $ (72,348)  $ (57,687)  $ (35,949)
       
Deemed dividend related to beneficial conversion feature of Series E convertible preferred stock --  $ (405) --
       
Net loss attributed to common shareholders  $ (72,348)  $ (58,092)  $ (35,949)
       
       
Net loss per share attributed to common stockholders — basic and diluted  $ (2.40)  $ (13.60)  $ (386.56)
       
Weighted-average shares of common stock outstanding used in computing net loss per share—basic and diluted 30,179,126 4,271,176 92,998
 
 
Complete Genomics, Inc.
Consolidated Statements of Operations
(in thousands, except share and per share amounts)
(unaudited)
     
  Three months ended 
December 31,
  2011 2010
     
Revenue  $ 2,469  $ 3,803
     
Costs and expenses:    
Cost of revenues  7,423 --
Start-up production costs --  4,903
Research and development  8,309  5,640
General and administrative  3,981  2,153
Sales and marketing  4,307  1,981
     
Total costs and expenses  24,020  14,677
     
Loss from operations  (21,551)  (10,874)
     
Interest expense  (783)  (775)
Interest and other income (expense), net  12  1,385
     
Net loss   $ (22,322)  $ (10,264)
     
     
Net loss per share attributed to common stockholders — basic and diluted  $ (0.67)  $ (0.69)
     
Weighted-average shares of common stock outstanding used in computing net loss per share—basic and diluted 33,276,980 14,820,222
 
 
Complete Genomics, Inc.
Consolidated Balance Sheets
(in thousands)
     
  December 31,
2011
December 31,
2010
     
Assets    
Current assets    
Cash and cash equivalents  $ 77,074  $ 68,918
Investments 6,000 --
Accounts receivable, net 6,488 4,943
Inventory  4,121  3,980
Prepaid expenses  1,141  1,101
Other current assets 341 78
     
Total current assets  95,165  79,020
Property and equipment, net 33,592 23,843
Other assets  1,446  297
     
Total assets  $ 130,203  $ 103,160
     
Liabilities and Stockholders' Equity    
Current liabilities    
Accounts payable  $ 5,363  $ 3,066
Accrued liabilities 5,400 3,102
Notes payable, current 7,099 5,780
Deferred revenue 10,026 5,739
     
Total current liabilities  27,888  17,687
Notes payable, net of current 16,162 7,521
Deferred rent, net of current 3,539 4,316
     
     
Total liabilities  47,589  29,524
     
Stockholders' Equity    
Preferred stock  --   -- 
Common stock 33 26
Additional paid-in capital 293,777 212,458
Retained deficit  (211,196)  (138,848)
     
Total stockholders' equity   82,614  73,636
Total liabilities and stockholders' equity   $ 130,203  $ 103,160
CONTACT: Complete Genomics, Inc.
         Scott Sandler
         Investor Relations
         (650) 943-2788
         ssandler@completegenomics.com