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Exhibit 10.1

AMENDMENT NO. 1 TO

ARENA PHARMACEUTICALS, INC.

AMENDED AND RESTATED SEVERANCE BENEFIT PLAN

The Arena Pharmaceuticals, Inc., Amended and Restated Severance Benefit Plan, originally effective on January 20, 2006, and amended and restated on December 30, 2008 (as amended, the “Plan ”), is hereby further amended as of February 10, 2012, by this Amendment No. 1 as follows:

Exhibit A of the Plan is deleted and replaced with Exhibit A to this Amendment No. 1.

To record the adoption of this Amendment No. 1, Arena Pharmaceuticals, Inc., has caused its duly authorized officer to execute the same this 13th day of February 2012.

 

Arena Pharmaceuticals, Inc.

/s/ Jack Lief

Jack Lief
President and Chief Executive Officer


EXHIBIT A

 

PARTICIPANT:

   SEVERANCE PERIOD (IN MONTHS):

JACK LIEF

   18

DOMINIC BEHAN

   18

STEVEN SPECTOR

   18

WILLIAM SHANAHAN

   12

ROBERT HOFFMAN

   12