Exhibit 99.1

MEDICIS REPORTS THIRD QUARTER 2011 RESULTS

SCOTTSDALE, Ariz.—November 8, 2011—Medicis (NYSE:MRX) today announced revenues of approximately $184.7 million for the three months ended September 30, 2011, compared to revenues of approximately $177.1 million for the three months ended September 30, 2010, which represents an increase of approximately $7.6 million, or approximately 4.3%.

Non-generally accepted accounting principles (non-GAAP, defined below) diluted earnings per share (EPS, defined below) for the three months ended September 30, 2011, was $0.56, compared to non-GAAP diluted EPS of $0.67 for the three months ended September 30, 2010, which represents a decrease of $0.11 per diluted share, or approximately 16.1% (see “Unaudited Reconciliation of Non-GAAP Adjustments” in the financial tables of this press release). This decrease is due primarily to increases in research and development (R&D) and promotional costs. GAAP diluted EPS for the three months ended September 30, 2011, was $0.29, compared to GAAP diluted EPS of $0.42 for the three months ended September 30, 2010.

The Company’s achievement of approximately $184.7 million in revenues and non-GAAP diluted EPS of $0.56 is consistent with the Company’s published guidance of $175-$195 million in revenues and $0.48-$0.67 in non-GAAP diluted EPS for the three months ended September 30, 2011.

“We are pleased to announce a strong quarter,” said Jonah Shacknai, Chairman and Chief Executive Officer of Medicis. “During the quarter, all of the Company’s primary brands demonstrated meaningful growth, despite a challenging economy. RESTYLANE^® received an expanded indication to include lip augmentation. We announced the divesture of LipoSonix^®, and look forward to participating in its future success with a partner focused in that category of aesthetics. We continue to believe SOLODYN^® prescriptions can grow, even with the imminent entrance of generic forms of the Legacy Strengths.¹ We also remain optimistic regarding business development opportunities and our substantial research and development pipeline.”

Non-GAAP net income for the three months ended September 30, 2011, was approximately $38.7 million, compared to non-GAAP net income of approximately $44.1 million for the three months ended September 30, 2010, which represents a decrease of approximately $5.4 million, or approximately 12.2%. Non-GAAP net income for the three months ended September 30, 2011, excludes charges totaling approximately $30.9 million (pre-tax), consisting of R&D upfront and milestone payments to Medicis partners of $21.0 million, professional fees of $2.5 million related to legal settlements, a $2.3 million write-down of an intangible asset relating to the carrying value of the royalty stream associated with a profit-sharing arrangement with a Medicis development partner and a loss from discontinued operations of approximately $5.2 million associated with the LipoSonix business, partially offset by approximately $0.1 million related to a benefit from fluctuations in the Company’s stock price and the resulting effect on the Company’s Stock Appreciation Rights (SARs). Non-GAAP net income for the three months ended September 30, 2010, excluded charges totaling approximately $17.5 million (pre-tax), consisting of an upfront R&D payment to a Medicis partner of $5.0 million, professional fees of approximately $0.9 million related to entering into the collaboration agreement with such partner, an approximately $2.3 million write-down of an intangible asset related to the planned discontinuation of certain non-primary products and a loss from discontinued operations of approximately $9.3 million associated with the LipoSonix business. GAAP net income for the three months ended September 30, 2011, was approximately $19.5 million, compared to GAAP net income of approximately $27.6 million for the three months ended September 30, 2010.

Acne Products

Medicis recorded revenues of approximately $119.1 million from sales of its acne products for the three months ended September 30, 2011, compared to revenues of approximately $118.5 million for the three months ended September 30, 2010, which represents an increase of approximately $0.6 million, or approximately 0.5%. This increase includes the impact from the early 2011 discontinuation of TRIAZ^® and the Company’s decision to no longer promote PLEXION^®. Sales of continuing acne products increased approximately $12.1 million, or approximately 11.3%, year-over-year, even without sales of the Legacy Strengths of SOLODYN in the three months ended September 30, 2011. The Medicis Acne Products category includes primarily SOLODYN and ZIANA^®.

Non-Acne Products

Medicis recorded revenues of approximately $55.7 million associated with its non-acne products for the three months ended September 30, 2011, compared to revenues of approximately $49.5 million for the three months ended September 30, 2010, which represents an increase of approximately $6.2 million, or approximately 12.4%. This increase is due primarily to increased sales of the RESTYLANE franchise and VANOS^®. The Medicis Non-Acne Products category includes primarily DYSPORT^®, PERLANE^®, RESTYLANE and VANOS.

Other Non-Dermatological Products

Medicis recorded revenues of approximately $9.9 million associated with its other non-dermatological products for the three months ended September 30, 2011, compared to revenues of approximately $9.1 million for the three months ended September 30, 2010, which represents an increase of approximately $0.8 million, or approximately 8.8%. The Medicis Other Non-Dermatological Products category includes primarily AMMONUL^®, BUPHENYL^® and contract revenue.

Other Income Statement Items

Gross profit margin for the three months ended September 30, 2011, was approximately 90.7%.

Selling, general and administrative (SG&A) expense for the three months ended September 30, 2011, was approximately $93.2 million, or approximately 50.5% of revenues, compared to approximately $78.1 million, or approximately 44.1% of revenues, for the three months ended September 30, 2010. SG&A expense for the three months ended September 30, 2011, includes $2.5 million of professional fees related to legal settlements. SG&A expense for the three months ended September 30, 2010, included approximately $0.9 million of professional fees related to entering into a strategic collaboration agreement with a Medicis partner.

R&D expense for the three months ended September 30, 2011, was approximately $28.7 million, compared to approximately $8.7 million for the three months ended September 30, 2010. R&D expense for the three months ended September 30, 2011, includes purchased R&D charges of $21.0 million associated with upfront and milestone payments to Medicis partners. R&D expense for the three months ended September 30, 2010, included a $5.0 million upfront payment to a Medicis partner.

Cash Flow

Cash flow from continuing operations for the nine months ended September 30, 2011, was approximately $186.0 million, which excludes $37.0 million associated with upfront and milestone payments to Medicis partners and professional fees related to legal settlements. The Company anticipates exceeding its objective of approximately $200 million in cash flow from continuing operations for the full year.

2011 Guidance

Based upon information available currently to the Company’s management, the Company’s financial guidance for the remainder of 2011 is anticipated as follows:

Additional 2011 Guidance Considerations

The above guidance does not take into account the following:

At the time of this disclosure, Medicis believes these objectives are attainable based upon information currently available to the Company’s management.

Diluted Earnings Per Share

Diluted earnings per share amounts are calculated using the “if-converted” method of accounting regardless of whether the Company’s outstanding convertible bonds meet the criteria for conversion and regardless of whether the bondholders actually convert their bonds into shares.

Use of Non-GAAP Financial Information

The Company has disclosed non-GAAP financial information in this press release to provide meaningful supplemental information regarding its operational performance and to enhance its investors’ overall understanding of its core financial performance. Management measures the Company’s performance using non-GAAP financial measures, such as those that are disclosed in this press release. This information facilitates management’s internal comparisons to the Company’s historical core operating results and competitors’ core operating results, and is a basis for financial decision making. Management believes that Medicis’ investors benefit from seeing the Company’s results on the same basis as management, in addition to the GAAP presentation. In our view, the non-GAAP financial measures are informative to investors, allowing them to focus on the ongoing operations and core results of Medicis’ business. Historically, Medicis has reported similar non-GAAP information to its investors and believes that the inclusion of comparative numbers provides consistency in the Company’s financial disclosures. This information is not in accordance with, or an alternative for, information prepared using GAAP. Non-GAAP net income excludes certain items, such as R&D charges which result from payments made to Medicis partners, transaction costs, the impairment of long-lived assets, gains resulting from the sale of subsidiaries, charges related to the accounting for our investment in Revance or Hyperion and litigation reserves. These items may have a material effect on the Company’s net income and diluted earnings per common share calculated in accordance with GAAP. The Company excludes such charges and the related tax benefits when analyzing its financial results as the items are distinguishable events. Management believes that, by viewing the Company’s results of operations excluding these charges, investors are given an indication of the ongoing results of the Company’s operations.

About Medicis

Medicis is the leading independent specialty pharmaceutical company in the United States focusing primarily on the treatment of dermatological and aesthetic conditions. The Company is dedicated to helping patients attain a healthy and youthful appearance and self-image. Medicis has leading branded prescription products in a number of therapeutic and aesthetic categories. The Company’s products have earned wide acceptance by both physicians and patients due to their clinical effectiveness, high quality and cosmetic elegance.

The Company’s products include the brands DYSPORT^® (abobotulinumtoxinA) 300 Units for Injection, PERLANE^® Injectable Gel, PERLANE-L^® Injectable Gel with 0.3% Lidocaine, RESTYLANE^® Injectable Gel, RESTYLANE-L^® Injectable Gel with 0.3% Lidocaine, LOPROX^® (ciclopirox) Gel 0.77% and Shampoo 1%, SOLODYN^® (minocycline HCl, USP) Extended Release Tablets, VANOS^® (fluocinonide) Cream, 0.1%, ZIANA^® (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, AMMONUL^® (sodium phenylacetate and sodium benzoate) Injection 10%/10%, BUPHENYL^® (sodium phenylbutyrate) Tablets and Powder and the over-the-counter brand ESOTERICA^®.

For more information about Medicis, please visit the Company’s website at www.Medicis.com. Printed copies of the Company’s complete audited financial statements are available free of charge upon request.

Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act. All statements included in this press release that address activities, events or developments that Medicis expects, believes or anticipates will or may occur in the future are forward-looking statements, including:

These statements are based on certain assumptions made by the Company based on its experience and perception of historical trends, current conditions, expected future developments and other factors it believes are appropriate in the circumstances. No assurances can be given, however, that these activities, events or developments will occur or that such results will be achieved. Such statements are subject to a number of assumptions, risks and uncertainties, many of which are beyond the control of the Company. The Company’s business is subject to all risk factors outlined in the Company’s most recent annual report on Form 10-K for the year ended December 31, 2010, and other documents we file with the SEC. At the time of this press release, the Company cannot, among other things, assess the likelihood, timing or forthcoming results of R&D projects, the risks associated with the FDA approval process and risks associated with significant competition within the Company’s industry, nor can the Company validate its assumptions of the full impact on its business of the approval of competitive generic versions of the Company’s primary brands, and any future competitive product approvals that may affect the Company’s brands.

Additionally, Medicis may acquire and/or license products or technologies from third parties to enter into new strategic markets. The Company periodically makes up-front, non-refundable payments to third parties for R&D work that has been completed and periodically makes additional non-refundable payments for the achievement of various milestones. There can be no certainty about the periods in which these potential payments could be made, nor if any payments such as these will be made at all. Any estimated future guidance does not include, among other things, the potential payments associated with any such transactions.

There are a number of additional important factors that could cause actual results to differ materially from those projected, including:

Forward-looking statements represent the judgment of the Company’s management as of the date of this release and the Company disclaims any intent or obligation to update any forward-looking statements contained herein, which speak as of the date hereof.

NOTE: Full prescribing information for any of the Company’s prescription products is available by contacting the Company. All trademarks are the property of their respective owners.

Medicis Pharmaceutical Corporation

Summary Statements of Operations (Unaudited)

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Medicis Pharmaceutical Corporation

Unaudited Reconciliation of Non-GAAP Adjustments

(in thousands, except per share data)

Medicis Pharmaceutical Corporation

Unaudited Reconciliation of Non-GAAP Adjustments

(in thousands, except per share data)

Medicis Pharmaceutical Corporation

Balance Sheets

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