Attached files

file filename
EX-99.4 - EX-99.4 - THERAVANCE INCa11-26866_1ex99d4.htm
EX-99.1 - EX-99.1 - THERAVANCE INCa11-26866_1ex99d1.htm
EX-99.2 - EX-99.2 - THERAVANCE INCa11-26866_1ex99d2.htm
EX-99.3 - EX-99.3 - THERAVANCE INCa11-26866_1ex99d3.htm

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC  20549

 


 

FORM 8-K

 


 

Current Report Pursuant

to Section 13 or 15(d) of the

Securities Exchange Act of 1934

 

Date of Report (Date of earliest event Reported):  September 25, 2011

 


 

THERAVANCE, INC.

(Exact Name of Registrant as Specified in its Charter)

 


 

Delaware

(State or Other Jurisdiction of
Incorporation)

 

000-30319

(Commission File Number)

 

94-3265960

(I.R.S. Employer Identification Number)

 

901 Gateway Boulevard
South San Francisco, California 94080
(650) 808-6000

(Addresses, including zip code, and telephone numbers, including area code, of principal executive offices)

 


 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

o            Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

o            Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

o            Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

o            Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

 

 



 

Item 8.01 Other Events.

 

On September 25, 2011, at the European Respiratory Society Annual Congress in Amsterdam, Netherlands, GlaxoSmithKline (GSK) presented three posters on the Phase 2 and 2b studies of GSK573719 (‘719), a long-acting muscarinic antagonist (LAMA), in patients with chronic obstructive pulmonary disease (COPD).  ‘719 is the LAMA component in LAMA/LABA (‘719/Vilanterol), an investigational product being developed under the LABA collaboration between GSK and Theravance, Inc. for the treatment of COPD.

 

GSK also presented a poster on the Phase 2a study of GSK961081 (‘081), an investigational compound within the inhaled bifunctional muscarinic antagonist-beta2 agonist (MABA) program that was licensed to GSK from Theravance in 2005 under the companies’ Strategic Alliance Agreement.

 

The four posters are attached hereto as Exhibits 99.1 to 99.4 and are incorporated herein by reference.

 

Item 9.01 Financial Statements and Exhibits.

 

(d)         Exhibits

 

Exhibit

 

Description

Exhibit 99.1

 

Dose-related efficacy of GSK573719, a new long-acting muscarinic receptor antagonist (LAMA) offering sustained 24-hour bronchodilation in COPD

 

 

 

Exhibit 99.2

 

Phase II study of once-daily GSK573719 Inhalation Powder, a new long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD)

 

 

 

Exhibit 99.3

 

Safety, pharmacokinetics (PK) and pharmacodynamics (PD) of single doses of GSK573719 Inhalation Powder, a new long-acting muscarinic antagonist (LAMA), in patients with COPD

 

 

 

Exhibit 99.4

 

The pharmacodynamics of GSK961081 in patients with COPD

 

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SIGNATURE

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

THERAVANCE, INC.

 

 

 

Date: September 26, 2011

By:

/s/ Michael W. Aguiar

 

 

Michael W. Aguiar

 

 

Chief Financial Officer

 

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EXHIBIT INDEX

 

Exhibit

 

Description

Exhibit 99.1

 

Dose-related efficacy of GSK573719, a new long-acting muscarinic receptor antagonist (LAMA) offering sustained 24-hour bronchodilation in COPD

 

 

 

Exhibit 99.2

 

Phase II study of once-daily GSK573719 Inhalation Powder, a new long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD)

 

 

 

Exhibit 99.3

 

Safety, pharmacokinetics (PK) and pharmacodynamics (PD) of single doses of GSK573719 Inhalation Powder, a new long-acting muscarinic antagonist (LAMA), in patients with COPD

 

 

 

Exhibit 99.4

 

The pharmacodynamics of GSK961081 in patients with COPD

 

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