Baxter International Inc. One Baxter Parkway Deerfield, IL 60015

FOR IMMEDIATE RELEASE

Media Contact:
Deborah Spak, (847) 948-2349

Investor Contacts:
Mary Kay Ladone, (847) 948-3371
Clare Trachtman, (847) 948-3085

BAXTER’S FIRST QUARTER FINANCIAL RESULTS EXCEED GUIDANCE

Company Raises Financial Outlook For 2011

DEERFIELD, Ill., April 21, 2011 — Baxter International Inc. (NYSE:BAX) today announced strong financial results for the first quarter of 2011, and raised its outlook for full-year 2011.

     Baxter reported net income in the first quarter of $570 million and earnings per diluted share of $0.98, which exceed the company’s previously-issued earnings guidance of $0.92 to $0.94 per diluted share. On an adjusted basis, excluding special items in the first quarter of 2010, Baxter’s earnings per diluted share increased 5 percent from $0.93 per diluted share in the prior-year period. Baxter’s financial results for the first quarter 2010 included after-tax special items totaling $627 million (or $1.04 per diluted share) related to the COLLEAGUE infusion pump and a change in the tax treatment of post-retirement prescription drug benefits.

     Worldwide sales totaled $3.3 billion and increased 12 percent compared to sales of $2.9 billion in the first quarter of 2010, which included a revenue

BAXTER REPORTS 1st QUARTER FINANCIAL RESULTS — Page 2

adjustment of $213 million associated with the COLLEAGUE infusion pump. Excluding the COLLEAGUE adjustment, Baxter’s worldwide sales increased 5 percent over the prior year.

     Excluding the impact of foreign currency as well as the COLLEAGUE adjustment, worldwide sales in the first quarter advanced 5 percent. Sales within the United States increased 10 percent to $1.4 billion, while international sales of $1.9 billion grew 1 percent.

     By business, BioScience revenues totaled $1.4 billion and rose 3 percent (or 4 percent excluding the impact of foreign currency). Contributing to this performance was robust demand for GAMMAGARD LIQUID [Immune Globulin Intravenous (Human)] (marketed as KIOVIG outside of the United States), certain specialty plasma-based therapeutics, and biosurgery products.

     Medical Products sales advanced 20 percent to $1.9 billion from $1.6 billion recorded in the prior year that included the COLLEAGUE adjustment referenced earlier. Excluding the adjustment and the impact of foreign currency, Medical Products sales increased 5 percent. This performance is primarily attributable to double-digit growth in the IV Therapies and Global Injectables product categories, driven by strong demand for intravenous (IV) and nutritional therapies, and a broad range of generic and pre-mixed injectable drugs. Medical Products also now includes Renal products.

     “We continue to implement measures to improve our commercial, operational, and scientific effectiveness in response to an evolving and challenging environment,” said Robert L. Parkinson, Jr., chairman and chief executive officer. “Baxter’s strong financial position provides us the flexibility to

BAXTER REPORTS 1st QUARTER FINANCIAL RESULTS — Page 3

invest in and pursue opportunities that expand our diverse product portfolio with innovative products that save and sustain patient lives and position our company for enhanced growth.”

Recent Highlights

     Baxter continues to expand its pipeline through investments in research and development as evidenced by a number of recent achievements:

	•		The launch of the first and only 30-gram dose vial for GAMMAGARD LIQUID (marketed as KIOVIG in Europe) in the United States. This new dosage form is the most frequently prescribed dose and is expected to enhance convenience for patients.
	•		The expanded approval throughout Europe of PREFLUCEL, a seasonal influenza vaccine, under the European repeat mutual recognition procedure (rMRP) by the Austrian Agency for Health and Food Safety. PREFLUCEL is manufactured using Vero cell technology, Baxter’s proprietary technology platform, offering an innovative method of vaccine production compared to conventional embryonated chicken egg production. The 13 participating European Union countries will formally implement the license on a national level to make PREFLUCEL available for the 2011-12 influenza season.
	•		The launch of OLIMEL parenteral nutrition solution in Canada. OLIMEL, which is also available throughout Europe, is the country’s first triple-chamber container for parenteral nutrition, providing adult patients with the essential ingredients of balanced nutrition — protein, carbohydrates and lipids (fats) — in a single container, simplifying the preparation of parenteral nutrition for hospitalized patients.
	•		The submission of a Biological License Application to the U.S. Food and Drug Administration (FDA) for TISSEEL [Fibrin Sealant (Human)] as a hemostatic agent in vascular surgery. TISSEEL is a fibrin sealant currently indicated for use as an adjunct to hemostasis in surgeries involving cardiopulmonary bypass and treatment of blunt or penetrating splenic injuries when control of bleeding by conventional surgical techniques and cautery is ineffective or impractical.
	•		The presentation of results of a phase III study evaluating the safety and efficacy of ARTISS [Fibrin Sealant (Human)] in 75 patients. ARTISS is a fibrin sealant currently indicated to adhere autologous skin grafts to surgically prepared wound beds, resulting from burns in adult and pediatric

BAXTER REPORTS 1st QUARTER FINANCIAL RESULTS — Page 4

populations greater than or equal to one year of age. Baxter currently has an efficacy supplement application pending with the FDA for an indication extension for use in facelift surgery.

•

The announcement of a definitive agreement to acquire privately-held Prism Pharmaceuticals, Inc., a specialty pharmaceutical company based in King of Prussia, PA. Prism Pharmaceuticals has developed and received FDA approval for multiple presentations of NEXTERONE® (amiodarone HCl), an antiarrhythmic agent, including the first and only ready-to-use premixed IV formulations, making this life-saving medication readily available in critical-care, time-sensitive circumstances.

Outlook for Second Quarter and Full-Year 2011

     Baxter also announced today its guidance for the second quarter of 2011 and updated its guidance for the full year.

     For full-year 2011, Baxter now expects to achieve sales growth, excluding the impact of foreign currency, of 3 to 4 percent, and earnings per diluted share, before special items, of $4.20 to $4.28 per diluted share. In addition, the company continues to expect cash flows from operations of approximately $2.8 billion. This guidance incorporates the impact of the previously-announced divestiture of the U.S. generic injectables business, now projected to close during the second quarter.

     Baxter’s previous guidance for full-year 2011 was sales growth, excluding the impact of foreign currency, of 2 to 3 percent, earnings per diluted share of $4.15 to $4.25, before any special items, and cash flows from operations of approximately $2.8 billion.

     For the second quarter of 2011, the company expects sales growth, excluding the impact of foreign currency, of 4 to 5 percent, and earnings per diluted share of $1.01 to $1.03, before any special items.

BAXTER REPORTS 1st QUARTER FINANCIAL RESULTS — Page 5

     A webcast of Baxter’s first quarter conference call for investors can be accessed live from a link on the company’s website at www.baxter.com beginning at 7:30 a.m. CDT on April 21, 2011. Please visit Baxter’s website for more information regarding this and future investor events and webcasts, including the company’s Annual Meeting of Shareholders on May 3, 2011.

     Baxter International Inc., through its subsidiaries, develops, manufactures and markets products that save and sustain the lives of people with hemophilia, immune disorders, infectious diseases, kidney disease, trauma, and other chronic and acute medical conditions. As a global, diversified healthcare company, Baxter applies a unique combination of expertise in medical devices, pharmaceuticals and biotechnology to create products that advance patient care worldwide.

This release includes forward-looking statements concerning the company’s financial results, outlook for 2011 and R&D pipeline. The statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those in the forward-looking statements: demand for and market acceptance risks for new and existing products, such as ADVATE, and other technologies; future actions of regulatory bodies and other governmental authorities, including with respect to the company’s implementation of the COLLEAGUE recall, that could delay, limit or suspend product development, manufacturing or sales or result in sanctions; product quality or patient safety concerns leading to product recalls, withdrawals, launch delays, litigation, or declining sales; Sigma’s ability to build production capacity to meet customer demand; future actions of governmental authorities and other third parties as U.S. healthcare reform legislation and other austerity measures are implemented; additional legislation, regulation and other governmental pressures, which may affect pricing, reimbursement and rebate policies of government agencies and private payers or other elements of the company’s business; product development risks; inventory reductions or fluctuations in buying patterns by wholesalers or distributors; the impact of geographic and product mix on the company’s sales; the impact of competitive products and pricing, including generic competition, drug reimportation and disruptive technologies; the availability of acceptable raw materials and component supply; fluctuations in supply and demand and the pricing of plasma-based therapies; the ability to enforce company patents; patents of third parties

BAXTER REPORTS 1st QUARTER FINANCIAL RESULTS — Page 6

preventing or restricting the company’s manufacture, sale or use of affected products or technology; any impact of the current economic conditions on Baxter and its customers; foreign currency fluctuations and other risks identified in the company’s most recent filing on Form 10-K and other Securities and Exchange Commission filings, all of which are available on the company’s website. The company does not undertake to update its forward-looking statements. Financial schedules are attached to this release and available on the company’s website.

# # #

BAXTER — PAGE 7

BAXTER INTERNATIONAL INC.
Consolidated Statements of Income (Loss)
Three Months Ended March 31, 2011 and 2010
(unaudited)
(in millions, except per share and percentage data)

		Three Months Ended
		March 31,
		2011				2010				Change
NET SALES		$	3,284			$	2,927	A			12%
COST OF SALES			1,609				1,884	A			(15%	)
GROSS MARGIN			1,675				1,043				61%
% of Net Sales			51.0%				35.6%			15.4 pts
MARKETING AND ADMINISTRATIVE EXPENSES			716				683				5%
% of Net Sales			21.8%				23.3%			(1.5 pts)
RESEARCH AND DEVELOPMENT EXPENSES			214				227				(6%	)
% of Net Sales			6.5%				7.8%			(1.3 pts)
NET INTEREST EXPENSE			10				19				(47%	)
OTHER EXPENSE, NET			4				2				100%
PRE-TAX INCOME			731				112				N/M
INCOME TAX EXPENSE			154				172	B			(10%	)
% of Pre-Tax Income			21.1%				153.6%			(132.5 pts)
NET INCOME (LOSS)			577				(60	)			N/M
LESS: NONCONTROLLING INTERESTS			7				3				133%
NET INCOME (LOSS) ATTRIBUTABLE TO BAXTER		$	570			$	(63	)			N/M
BASIC EPS		$	0.99			$	(0.11	)			N/M
DILUTED EPS		$	0.98			$	(0.11	)			N/M
WEIGHTED-AVERAGE NUMBER OF COMMON SHARES OUTSTANDING
Basic			577				602
Diluted			581				602
ADJUSTED PRE-TAX INCOME (excluding specified items)		$	731			$	700	C			4%
ADJUSTED NET INCOME ATTRIBUTABLE TO BAXTER (excluding specified items)		$	570			$	564	C			1%
ADJUSTED DILUTED EPS (excluding specified items)		$	0.98			$	0.93	C			5%

BAXTER — PAGE 8

BAXTER INTERNATIONAL INC.
Note to Consolidated Statements of Income (Loss)
Three Months Ended March 31, 2011 and 2010
Description of Adjustments and Reconciliation of GAAP to Non-GAAP Measures
(unaudited)
(in millions, except per share and percentage data)

The company’s GAAP results for the three months ended March 31, 2010 included specified items which impacted the GAAP results as follows:

		Three Months Ended March 31,
		2011				2010
										Total				Excluding
										specified				specified
		GAAP		1		GAAP				items		2		items				Change		3
NET SALES		$	3,284			$	2,927			$	213			$	3,140				5%
COST OF SALES			1,609				1,884				(375	)			1,509				7%
GROSS MARGIN			1,675				1,043				588				1,631				3%
% of Net Sales			51.0%				35.6%								51.9%			(0.9 pts)
MARKETING AND ADMINISTRATIVE EXPENSES			716				683				—				683				5%
% of Net Sales			21.8%				23.3%								21.8%			0 pts
RESEARCH AND DEVELOPMENT EXPENSES			214				227				—				227				(6%	)
% of Net Sales			6.5%				7.8%								7.2%			(0.7 pts)
NET INTEREST EXPENSE			10				19				—				19				(47%	)
OTHER EXPENSE, NET			4				2				—				2				100%
PRE-TAX INCOME			731				112				588				700				4%
INCOME TAX EXPENSE			154				172				(39	)			133				16%
% of Pre-Tax Income			21.1%				153.6%								19.0%			2.1 pts
NET INCOME (LOSS)			577				(60	)			627				567				2%
LESS: NONCONTROLLING INTERESTS			7				3				—				3				133%
NET INCOME (LOSS) ATTRIBUTABLE TO BAXTER		$	570			$	(63	)		$	627			$	564				1%
BASIC EPS		$	0.99			$	(0.11	)		$	1.05			$	0.94				5%
DILUTED EPS		$	0.98			$	(0.11	)		$	1.04			$	0.93				5%
WEIGHTED-AVERAGE NUMBER OF COMMON SHARES OUTSTANDING
Basic			577				602								602
Diluted			581				602	4							609	4

For more information on the company’s use of non-GAAP financial measures in this press release, please see the company’s Current Report on Form 8-K filed with the Securities and Exchange Commission on the date of this press release.

BAXTER — PAGE 9

BAXTER INTERNATIONAL INC.
Cash Flows from Operations and Changes in Net Debt
(unaudited)
($ in millions)

	Cash Flows from Operations
	(Brackets denote cash outflows)
							Three Months Ended
							March 31,
							2011				2010
	Net income (loss)						$	577			$	(60	)
	Adjustments
	Depreciation and amortization							158				166
	Deferred income taxes							91				91	A
	Stock compensation							28				30
	Realized excess tax benefits from stock issued under employee benefit plans							(5	)			(31	)
	COLLEAGUE infusion pump charge							—				588
	Other							8				9
	Changes in balance sheet items
	Accounts and other current receivables							(68	)			(33	)
	Inventories							(61	)			(94	)
	Accounts payable and accrued liabilities							(135	)			(101	)
	Business optimization and infusion pump payments							(60	)			(23	)
	Other							(162	) B			(263	) B
	Cash flows from operations						$	371			$	279
	Changes in Net Debt
	Increase (decrease)
							Three Months Ended
							March 31,
								2011				2010
	Net debt, beginning of period						$	1,702			$	1,365
	Cash flows from operations							(371	)			(279	)
	Capital expenditures							198				230
	Dividends							180				174
	Proceeds from stock issued under employee benefit plans							(129	)			(140	)
	Purchases of treasury stock							637				435
	Acquisitions and investments							14				234	C
	Other, including the effect of exchange rate changes							(25	)			61
	Increase in net debt							504				715
	Net debt, March 31						$	2,206			$	2,080
			March 31, 2011				March 31, 2010
	Key statistics, March 31:		GAAP				GAAP				Adjusted
	Days sales outstanding (DSO)			56.0				58.5	D			53.1	D
	Inventory turns			2.4				2.9	E			2.2	E
	Selected balance sheet information:						March 31, 2011				December 31, 2010
	Cash and equivalents						$	2,168			$	2,685
	Accounts and other current receivables						$	2,399			$	2,265
	Inventories						$	2,517			$	2,371
	Accounts payable and accrued liabilities						$	3,866			$	4,017

BAXTER — PAGE 10

BAXTER INTERNATIONAL INC.
Net Sales
Periods Ending March 31, 2011 and 2010
(unaudited)
($ in millions)

				Q1				Q1				% Growth @				% Growth @
				2011				2010				Actual Rates				Constant Rates
	BioScience
	United States			$	684			$	610				12%				12%
	International				724				752				(4%	)			(2%	)
	Total BioScience			$	1,408			$	1,362				3%				4%
	Medical Products  1
	United States  2			$	730			$	674				8%				8%
	International				1,138				1,092				4%				3%
	Total Medical Products - Adjusted  2			$	1,868			$	1,766				6%				5%
	COLLEAGUE infusion pump charge  2								(213	)
	Total Medical Products - GAAP  2			$	1,868			$	1,553				20%				19%
	Transfusion Therapies  3
	United States			$	8			$	9				(11%	)			(11%	)
	International				—				3				(100%	)			(100%	)
	Total Transfusion Therapies			$	8			$	12				(33%	)			(33%	)
	Baxter International Inc.
	United States  2			$	1,422			$	1,293				10%				10%
	International				1,862				1,847				1%				1%
	Total Baxter - Adjusted  2			$	3,284			$	3,140				5%				5%
	COLLEAGUE infusion pump charge  2								(213	)
	Total Baxter - GAAP  2			$	3,284			$	2,927				12%				12%

BAXTER — PAGE 11

BAXTER INTERNATIONAL INC.
GAAP Key Product Line Sales
Periods Ending March 31, 2011 and 2010
(unaudited)
($ in millions)

				GAAP				GAAP				% Growth @				% Growth @
				Q1 2011				Q1 2010				Actual Rates				Constant Rates
	BioScience
	Recombinants			$	512			$	510				0%				1%
	Plasma Proteins				308				292				5%				8%
	Antibody Therapy				374				322				16%				18%
	Regenerative Medicine				140				119				18%				18%
	Other  1				74				119				(38%	)			(39%	)
	Total BioScience			$	1,408			$	1,362				3%				4%
	Medical Products  2
	Renal			$	587			$	584				1%				(1%	)
	Global Injectables				517				451				15%				14%
	IV Therapies				428				391				9%				10%
	Infusion Systems  3				211				(4	)			N/M				N/M
	Anesthesia				118				127				(7%	)			(7%	)
	Other				7				4				75%				17%
	Total Medical Products  3			$	1,868			$	1,553				20%				19%
	Transfusion Therapies  4			$	8			$	12				(33%	)			(33%	)
	Total Baxter  3			$	3,284			$	2,927				12%				12%

BAXTER — PAGE 12

BAXTER INTERNATIONAL INC.
Adjusted Key Product Line Sales
Periods Ending March 31, 2011 and 2010
(unaudited)
($ in millions)

												Adjusted				Adjusted
				GAAP				Adjusted				% Growth @				% Growth @
				Q1 2011		1		Q1 2010				Actual Rates				Constant Rates
	BioScience
	Recombinants			$	512			$	510				0%				1%
	Plasma Proteins				308				292				5%				8%
	Antibody Therapy				374				322				16%				18%
	Regenerative Medicine				140				119				18%				18%
	Other  2				74				119				(38%	)			(39%	)
	Total BioScience			$	1,408			$	1,362				3%				4%
	Medical Products  3
	Renal			$	587			$	584				1%				(1%	)
	Global Injectables				517				451				15%				14%
	IV Therapies				428				391				9%				10%
	Infusion Systems - Adjusted  4				211				209				1%				0%
	Anesthesia				118				127				(7%	)			(7%	)
	Other				7				4				75%				17%
	Total Medical Products - Adjusted  4			$	1,868			$	1,766				6%				5%
	Transfusion Therapies  5			$	8			$	12				(33%	)			(33%	)
	Total Baxter - Adjusted  4			$	3,284			$	3,140				5%				5%

BAXTER — PAGE 13

BAXTER INTERNATIONAL INC.
Adjusted Key Product Line Sales by U.S. and International
Periods Ending March 31, 2011 and 2010
(unaudited)
($ in millions)

				GAAP													Adjusted													Adjusted
			Q1 2011 1													Q1 2010													% Growth
				U.S.				International				Total					U.S.				International				Total					U.S.				International				Total
	BioScience
	Recombinants			$	231			$	281			$	512				$	222			$	288			$	510					4%				(2%	)			0%
	Plasma Proteins				102				206				308					94				198				292					9%				4%				5%
	Antibody Therapy				265				109				374					223				99				322					19%				10%				16%
	Regenerative Medicine				78				62				140					62				57				119					26%				9%				18%
	Other  2				8				66				74					9				110				119					(11%	)			(40%	)			(38%	)
	Total BioScience			$	684			$	724			$	1,408				$	610			$	752			$	1,362					12%				(4%	)			3%
	Medical Products  3
	Renal			$	96			$	491			$	587				$	95			$	489			$	584					1%				0%				1%
	Global Injectables				291				226				517					250				201				451					16%				12%				15%
	IV Therapies				148				280				428					124				267				391					19%				5%				9%
	Infusion Systems - Adjusted  4				124				87				211					122				87				209					1%				0%				1%
	Anesthesia				70				48				118					82				45				127					(15%	)			7%				(7%	)
	Other				1				6				7					1				3				4					0%				100%				75%
	Total Medical Products - Adjusted  4			$	730			$	1,138			$	1,868				$	674			$	1,092			$	1,766					8%				4%				6%
	Transfusion Therapies  5			$	8			$	—			$	8				$	9			$	3			$	12					(11%	)			(100%	)			(33%	)
	Total Baxter - Adjusted  4			$	1,422			$	1,862			$	3,284				$	1,293			$	1,847			$	3,140					10%				1%				5%

BAXTER — PAGE 14

BAXTER INTERNATIONAL INC.
Reconciliation of GAAP to Non-GAAP Net Sales Measures
Periods Ending March 31, 2011 and 2010
(unaudited)
($ in millions)

The company’s GAAP net sales results for the period ended March 31, 2010 included a $213 million charge related to the recall of COLLEAGUE infusion pumps, which impacted GAAP net sales as follows:

																														% Growth @													% Growth @
			Q1 2011													Q1 2010													Actual Rates													Constant Rates
				U.S.				International				Total					U.S.				International				Total					U.S.				International				Total					U.S.				International			Total
	Infusion Systems - GAAP			$	124			$	87			$	211				$	(91	)		$	87			$	(4	)				N/M				0%				N/M												N/M
	COLLEAGUE infusion pump charge																	213								213
	Infusion Systems - Adjusted			$	124			$	87			$	211				$	122			$	87			$	209					1%				0%				1%												0%
	Total Medical Products - GAAP			$	730			$	1,138			$	1,868				$	461			$	1,092			$	1,553					58%				4%				20%					58%				3%			19%
	COLLEAGUE infusion pump charge																	213								213
	Total Medical Products - Adjusted			$	730			$	1,138			$	1,868				$	674			$	1,092			$	1,766					8%				4%				6%					8%				3%			5%
	Total Baxter - GAAP			$	1,422			$	1,862			$	3,284				$	1,080			$	1,847			$	2,927					32%				1%				12%					32%				1%			12%
	COLLEAGUE infusion pump charge																	213								213
	Total Baxter - Adjusted			$	1,422			$	1,862			$	3,284				$	1,293			$	1,847			$	3,140					10%				1%				5%					10%				1%			5%

For more information on the company’s use of non-GAAP financial measures in this press release, please see the company’s Current Report on Form 8-K filed with the Securities and Exchange Commission on the date of this press release.