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10-K - 10-K - INCYTE CORPa2202084z10-k.htm
EX-31.2 - EX-31.2 - INCYTE CORPa2202084zex-31_2.htm
EX-31.1 - EX-31.1 - INCYTE CORPa2202084zex-31_1.htm
EX-32.2 - EX-32.2 - INCYTE CORPa2202084zex-32_2.htm
EX-23.1 - EX-23.1 - INCYTE CORPa2202084zex-23_1.htm
EX-32.1 - EX-32.1 - INCYTE CORPa2202084zex-32_1.htm
EX-21.1 - EX-21.1 - INCYTE CORPa2202084zex-21_1.htm

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EXHIBIT 12.1

COMPUTATION OF RATIOS OF EARNINGS TO FIXED CHARGES

 
  Year Ended December 31,  
 
  2006   2007   2008   2009   2010  
 
  (in thousands)
 

Net income (loss) before income taxes

  $ (74,166 ) $ (86,881 ) $ (178,920 ) $ (211,870 ) $ (31,846 )

Fixed charges

    19,362     25,553     26,537     29,166     24,047  
                       
 

Total earnings and fixed charges

    (54,804 )   (61,328 )   (152,383 )   (182,704 )   (7,799 )
                       

Fixed charges

    19,362     25,553     26,537     29,166     24,047  
                       

Ratio of earnings to fixed charges(1)(2)

    NM     NM     NM     NM     NM  

(1)
The ratio of earnings to fixed charges is computed by dividing loss before taxes plus fixed charges by fixed charges. Fixed charges consist of interest expense (including interest expense from capital leases) and the estimated portion of rental expense deemed by us to be representative of the interest factor of rental payments under operating leases, plus amortization of debt issuance expenses. Earnings were insufficient to cover fixed charges by $74.2 million, $86.9 million, $178.9 million, $211.9 million and $31.8 million for the years ended December 31, 2006, 2007, 2008, 2009 and 2010 respectively.

(2)
NM—Not meaningful.



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COMPUTATION OF RATIOS OF EARNINGS TO FIXED CHARGES