Exhibit 99.1

DATE: February 15, 2011

FOR IMMEDIATE RELEASE

AMERICAN MEDICAL SYSTEMS CONFIRMS FOURTH QUARTER REVENUE AND FINISHES 2010 WITH STRONG FINANCIAL PERFORMANCE

	•		Fourth quarter revenue of $147.0 million grows 0.7%; 4.0% growth excluding impact of currency and previously divested Uterine Health product line
	•		Fourth quarter non-GAAP adjusted EPS of $0.40 grows 14.3% over prior year; GAAP EPS of $0.35 grows 16.7% over prior year
	•		Continued strong cash generation drives retirement of senior secured debt in the fourth quarter

MINNEAPOLIS, February 15, 2011 — American Medical Systems Holdings, Inc. (NASDAQ: AMMD) confirmed previously reported revenue of $147.0 million for the fourth quarter of 2010, a 0.7 percent increase over sales of $146.0 million in the comparable quarter of 2009. Adjusting for the negative impact of the stronger U.S. dollar in the fourth quarter of 2010 results in growth of 1.7 percent over the same quarter last year. Further adjusting revenue for the impact of the Her Option® uterine health product line, which was sold during the first quarter of 2010, results in constant currency revenue growth of 4.0 percent. Full year 2010 revenue of $542.3 million grew 4.4 percent over 2009 revenue of $519.3 million. Adjusting for the impact of foreign currency fluctuations, which was negative $0.1 million, and the impact of the Her Option® uterine health product line divestiture results in 2010 constant currency revenue growth of 5.9% over 2009.

Men’s Health sales of $65.2 million in the fourth quarter represented an increase of 2.7 percent on a reported basis compared to the same quarter last year, and grew 4.1 percent on a constant currency basis, with growth in the erectile restoration and male continence product lines roughly equal. The BPH Therapy business declined 2.1 percent on a reported basis and 1.0 percent on a constant currency basis to $32.6 million for the quarter. BPH Therapy sales were led by an enthusiastic response to the new GreenLight™ XPS console, offset by a decline in fiber sales due to limited availability of the recently launched MoXy™ Liquid Cooled Fiber and challenging international markets. The Women’s Health business increased 6.7 percent on a reported basis and 7.4 percent on a constant currency basis to $48.8 million in the fourth quarter. The female continence product line benefited from the recent introduction of the MiniArc® Precise Single-Incision Sling System for the treatment of female stress urinary incontinence, and the pelvic floor repair product line continued its strong performance driven by the success of both the Elevate® anterior and posterior systems.

The Company reported fourth quarter net income of $27.2 million, or $0.35 per share. This compares to net income in the same quarter last year of $22.3 million, or $0.30 per share, a growth of 16.7 percent. Non-GAAP adjusted earnings per share of $0.40 compares to $0.35 per share in the same quarter last year, a growth of 14.3 percent, finishing two cents above the top of guidance for the quarter. Full year 2010 net income of $87.0 million, or $1.12 per share, compares to full year 2009 income of $84.8 million, or $1.14 per share, a decline of 1.8 percent. Non-GAAP adjusted earnings per share for 2010 of $1.30 grew 12.1 percent over 2009 non-GAAP adjusted earnings per share of $1.16. Non-GAAP adjusted earnings per share excludes the

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impact of the amortization of intangible assets and amortization of financing costs, both significant non-cash items affecting comparability to other companies. Full year non-GAAP adjusted earnings per share in 2010 also excludes the gain on the sale of the Her Option® Uterine Health product line and in 2009 also excludes the respective gains on extinguishment of debt and sale of the Ovion technology. A reconciliation of reported net income to non-GAAP adjusted net income for all periods is provided in the attached schedules.

Tony Bihl, Chief Executive Officer, stated, “2010 was another record year of sales and earnings, including solid performance in the fourth quarter, particularly in the U.S., where revenues grew 7.4 percent. Our healthy growth in non-GAAP earnings per share of 14.3 percent in the fourth quarter is again reflective of our solid financial performance throughout 2010.” Mr. Bihl further commented, “We are pleased to report that as a result of consistently strong cash management, we celebrated a significant milestone event in the fourth quarter; the retirement of our senior secured debt, further strengthening our balance sheet.”

Outlook

The Company estimates 2011 revenue will be in the range of $555 million to $575 million and first quarter 2011 revenue in the range of $135 to $139 million. This guidance assumes foreign currency exchange rates remain constant with current rates.

Consistent with 2010, the Company has two significant non-cash charges in GAAP earnings that create inconsistencies in comparisons to many other companies; amortization of financing costs and amortization of intangible assets. In addition, in 2011 the Company will incur start-up costs in connection with the expansion of manufacturing capacity internationally, which will be incremental to on-going operations. Accordingly, the Company guides to non-GAAP adjusted earnings per share, which the Company defines as GAAP earnings per share excluding the impact of amortization of intangible assets and amortization of financing costs and in 2011, excluding the impact of start-up costs of global manufacturing expansion.

The Company estimates 2011 non-GAAP adjusted earnings per share will be in the range of $1.32 to $1.39 and first quarter 2011 non-GAAP adjusted earnings per share will be in the range of $0.29 to $0.32. This guidance excludes the impact of amortization of intangible assets which is approximately $0.09 and $0.025 per share for the full year 2011 and the first quarter, respectively, amortization of financing costs, which is approximately $0.11 and $0.025 for the full year 2011 and the first quarter, respectively, and the impact of start-up costs of global manufacturing expansion, which is approximately $5.0 million and $1.0 million, for the full year 2011 and the first quarter, respectively, or approximately $0.05 and $0.01 per share in 2011 and the first quarter, respectively. Guidance for both periods also excludes the impact of any unusual non-recurring items that could occur, such as gain or loss on early debt extinguishments, sale of non-strategic assets or in-process research and development charges (IPRD) on milestone payments related to prior acquisitions.

Use of Non-GAAP Financial Measures

In addition to financial measures prepared in accordance with U.S. generally accepted accounting principles (GAAP), management provides non-GAAP adjusted net income, non-GAAP adjusted earnings per share and constant currency revenue growth rates because management believes that in order to properly understand the Company’s short-term and long-term financial trends and for purposes of comparability to other companies, investors may wish to consider the impact of certain adjustments (such as gain or loss on extinguishment of debt, gain or loss on sale of non-strategic assets, IPRD charges, amortization of intangible assets, amortization of financing costs,

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start-up costs of global manufacturing expansion and related income tax adjustments and the impact of foreign currency translation on reported revenue). These adjustments result from facts and circumstances (such as acquisition, business development and expansion activities and other non-recurring items) that vary in frequency and impact on the Company’s results of operations, represent significant items, which when excluded provide a useful measure to determine the health of the business and earnings by the business before significant non-cash charges and costs of a start-up nature or in the case of foreign currency translation, are highly variable and difficult to predict. Management uses non-GAAP adjusted net income, non-GAAP adjusted earnings per share and constant currency revenue growth rates to forecast and evaluate the operational performance of the Company as well as to compare results of current periods to prior periods on a consistent basis.

A reconciliation of net income and revenue growth rate percentages, the GAAP measure most directly comparable to non-GAAP adjusted earnings per share and constant currency revenue growth rates, respectively, are provided on the attached schedules.

Non-GAAP financial measures used by the Company may be calculated differently from, and therefore may not be directly comparable to, similarly titled measures used by other companies. Investors should consider non-GAAP measures in addition to, and not as a substitute for, or superior to, financial performance measures prepared in accordance with GAAP.

Earnings Call Information

American Medical Systems will host a conference call on Tuesday, February 15, 2011 at 5:00 p.m. eastern time to discuss its 2010 fourth quarter and full year results. The Company will provide additional guidance for 2011 on this call. To listen to a live web cast of this conference call, access the web cast link at www.AMMD.com. Those without internet access may join the call from within the U.S. by dialing 877-312-4897; outside the U.S., dial 970-315-0301, and reference conference ID # 36574073.

A replay of the call will be available through the Company’s corporate website at www.AMMD.com, beginning three hours after the completion of the call and for 90 days following the call.

About American Medical Systems

American Medical Systems, headquartered in Minnetonka, Minnesota, is a diversified supplier of medical devices and procedures to treat incontinence, erectile dysfunction, benign prostatic hyperplasia (BPH), pelvic floor prolapse and other pelvic disorders in men and women. These disorders can significantly diminish one’s quality of life and profoundly affect social relationships. In recent years, the number of people seeking treatment has increased markedly as a result of longer lives, higher-quality-of-life expectations and greater awareness of new treatment alternatives. American Medical Systems’ products reduce or eliminate the incapacitating effects of these diseases, often through minimally invasive therapies. The Company’s products were used to treat approximately 340,000 patients in 2010.

Forward-Looking Statements

This press release contains forward-looking statements relating to the market opportunities, future products, sales and financial results of American Medical Systems. These statements and other statements contained in this press release that are not purely historical fact are forward-looking statements, within the meaning of the Private Securities Litigation Reform Act of 1995, that are based on management’s beliefs, certain assumptions and current expectations. These forward-

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looking statements are subject to risks and uncertainties such as successfully competing against competitors, timing and success of new product introductions; clinical and regulatory matters; current worldwide economic conditions, global healthcare reform, changes in and adoption of reimbursement rates; physician acceptance, endorsement, and use of AMS products; potential product recalls or technological obsolescence; patient acceptance of the Company’s products and therapies; factors impacting the stock market and share price and its impact on the dilution of convertible securities; ability of the Company’s manufacturing facilities to meet customer demand; reliance on single or sole-sourced suppliers; loss or impairment of a principal manufacturing facility; adequate protection of the Company’s intellectual property rights; product liability claims; successfully managing debt leverage and related credit facility financial covenants; currency and other economic risks inherent in selling our products internationally and other risks and uncertainties described in the Company’s Annual Report on Form 10-K for the year ended January 2, 2010, and its other SEC filings. Actual results may differ materially from anticipated results. The forward-looking statements contained in this press release are made as of the date hereof, and AMS undertakes no obligation to update any forward-looking statements to reflect events or circumstances after the date on which any such statement is made or to reflect the occurrence of unanticipated events.

More information about the Company and its products can be found at its website www.AmericanMedicalSystems.com and in the Company’s Annual Report on Form 10-K for 2009 and its other SEC filings.

Contact:		Mark Heggestad
		Executive Vice President and Chief Financial Officer
		952-930-6495
		Mark.Heggestad@AmericanMedicalSystems.com
		Anthony Bihl
		President and Chief Executive Officer
		952-930-6334
		Tony.Bihl@AmericanMedicalSystems.com

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American Medical Systems Holdings, Inc.
Statements of Operations

(In thousands, except per share data)

		Three Months Ended								Twelve Months Ended
		January 1, 2011				January 2, 2010				January 1, 2011				January 2, 2010
		(Unaudited)				(Unaudited)				(Unaudited)
Net sales		$	146,993			$	146,013			$	542,316			$	519,270
Cost of sales			25,321				25,977				91,116				92,211
Gross profit			121,672				120,036				451,200				427,059
Operating expenses
Selling, general and administrative			58,646				57,462				230,931				219,050
Research and development			13,391				14,354				53,367				52,765
Amortization of intangibles			3,038				3,137				12,168				13,161
Total operating expenses			75,075				74,953				296,466				284,976
Operating income			46,597				45,083				154,734				142,083
Other (expense) income
Royalty income			51				305				559				3,073
Interest expense			(3,181	)			(4,586	)			(14,048	)			(19,636	)
Amortization of financing costs			(3,535	)			(3,440	)			(14,077	)			(15,790	)
Gain on extinguishment of debt			—				—				—				10,125
Gain on sale of non-strategic assets			—				—				7,719				17,446
Other (expense) income			(855	)			(2,364	)			997				(1,266	)
Total other (expense) income			(7,520	)			(10,085	)			(18,850	)			(6,048	)
Income before income taxes			39,077				34,998				135,884				136,035
Provision for income taxes			11,864				12,726				48,874				51,197
Net income		$	27,213			$	22,272			$	87,010			$	84,838
Net income per share
Basic net income		$	0.36			$	0.30			$	1.15			$	1.14
Diluted net income			0.35				0.30				1.12				1.14
Weighted average common shares used in calculation
Basic			76,507				74,500				75,847				74,097
Diluted			77,522				75,412				77,632				74,675

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American Medical Systems Holdings, Inc.
Condensed Balance Sheets
(In thousands)

		January 1, 2011				January 2, 2010
		(Unaudited)
Assets
Current assets
Cash and short-term investments		$	77,815			$	50,538
Accounts receivable, net			98,518				102,590
Inventories, net			33,789				30,276
Other current assets			22,305				20,937
Total current assets			232,427				204,341
Property, plant and equipment, net			41,405				44,120
Goodwill and intangibles, net			774,501				792,467
Other long-term assets			5,101				6,223
Total assets		$	1,053,434			$	1,047,151
Liabilities and stockholders’ equity
Current liabilities
Accounts payable		$	8,833			$	9,114
Accrued liabilities and taxes			60,719				62,151
Total current liabilities			69,552				71,265
Debt and other long term liabilities			315,321				430,527
Total liabilities			384,873				501,792
Stockholders’ equity			668,561				545,359
Total liabilities and stockholders’ equity		$	1,053,434			$	1,047,151

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American Medical Systems Holdings, Inc.

Condensed Statements of Cash Flows

(In thousands)

		Twelve Months Ended
		January 1, 2011				January 2, 2010
		(Unaudited)
Cash flows from operating activities
Net income		$	87,010			$	84,838
Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation and amortization, including deferred financing costs			35,684				38,976
Gain on extinguishment of debt			—				(10,125	)
Gain on sale of non-strategic assets			(7,719	)			(17,446	)
Stock-based compensation			8,656				8,988
Other adjustments, including changes in operating assets and liabilities			(7,689	)			17,565
Net cash provided by operating activities			115,942				122,796
Cash flows from investing activities
Purchase of property, plant and equipment			(7,045	)			(5,865	)
Purchase of other intangibles			(3,149	)			(5,927	)
(Purchase) sale of short term investments, net			(41,442	)			11,935
Sale of non-strategic assets, net			19,043				18,982
Other cash flows from investing activities			76				(556	)
Net cash (used in) provided by investing activities			(32,517	)			18,569
Cash flows from financing activities
Payments on senior secured credit facility			(125,307	)			(103,510	)
Repurchase of convertible senior subordinated notes			—				(21,125	)
Debt issuance costs			—				(7,697	)
Other cash flows from financing activities			28,180				10,756
Net cash used in financing activities			(97,127	)			(121,576	)
Effect of currency exchange rates on cash and cash equivalents			(487	)			(761	)
Net (decrease) increase in cash and cash equivalents			(14,189	)			19,028
Cash and cash equivalents at beginning of period			30,670				11,642
Cash and cash equivalents at end of period		$	16,481			$	30,670

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American Medical Systems Holdings, Inc.
Selected Sales Information and Constant Currency Growth Reconciliation
(Unaudited)
(In thousands)

		Three Months Ended								Constant Currency Growth Reconciliation (a)
																		Percent Growth
										Percent				Currency				at Constant
		January 1, 2011				January 2, 2010				Growth				Impact				Currency
Sales
Men’s health		$	65,221			$	63,504				2.7	%		$	(866	)			4.1	%
BPH therapy			32,615				33,309				-2.1	%			(364	)			-1.0	%
Women’s health			48,816				45,750				6.7	%			(335	)			7.4	%
Sub-total			146,652				142,563				2.9	%			(1,565	)			4.0	%
Uterine health (b)			341				3,450				-90.1	%			—				-90.1	%
Total		$	146,993			$	146,013				0.7	%		$	(1,565	)			1.7	%
Geography
United States		$	106,491			$	99,112				7.4	%		$	—				7.4	%
International			40,161				43,451				-7.6	%			(1,565	)			-4.0	%
Sub-total			146,652				142,563				2.9	%			(1,565	)			4.0	%
United States-Uterine health (b)			341				3,450				-90.1	%			—				-90.1	%
Total		$	146,993			$	146,013				0.7	%		$	(1,565	)			1.7	%
Percent of total sales
Men’s health			44	%			43	%
BPH therapy			22	%			23	%
Women’s health			33	%			31	%
Sub-total			100	%			98	%
Uterine health (b)			0	%			2	%
Total			100	%			100	%
Geography
United States			73	%			70	%
International			27	%			30	%
Total			100	%			100	%

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American Medical Systems Holdings, Inc.
Selected Sales Information and Constant Currency Growth Reconciliation
(Unaudited)
(In thousands)

		Twelve Months Ended								Constant Currency Growth Reconciliation (a)
																		Percent Growth
										Percent				Currency				at Constant
		January 1, 2011				January 2, 2010				Growth				Impact				Currency
Sales
Men’s health		$	246,238			$	234,594				5.0	%		$	(216	)			5.1	%
BPH therapy			114,592				114,468				0.1	%			(138	)			0.2	%
Women’s health			177,247				159,367				11.2	%			216				11.1	%
Sub-total			538,077				508,429				5.8	%			(138	)			5.9	%
Uterine health (b)			4,239				10,841				-60.9	%			—				-60.9	%
Total		$	542,316			$	519,270				4.4	%		$	(138	)			4.5	%
Geography
United States		$	390,680			$	363,057				7.6	%		$	—				7.6	%
International			147,397				145,372				1.4	%			(138	)			1.5	%
Sub-total			538,077				508,429				5.8	%			(138	)			5.9	%
United States-Uterine health (b)			4,239				10,841				-60.9	%			—				-60.9	%
Total		$	542,316			$	519,270				4.4	%		$	(138	)			4.5	%
Percent of total sales
Men’s health			45	%			45	%
BPH therapy			21	%			22	%
Women’s health			33	%			31	%
Sub-total			99	%			98	%
Uterine health (b)			1	%			2	%
Total			100	%			100	%
Geography
United States			73	%			72	%
International			27	%			28	%
Total			100	%			100	%

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American Medical Systems Holdings, Inc.
Reconciliation of Reported Net Income to Non-GAAP Adjusted Net Income
(Adjustments are presented on a pre-tax basis)
(Unaudited)
(In thousands, except per share data)

		Three Months Ended								Twelve Months Ended
		January 1, 2011				January 2, 2010				January 1, 2011				January 2, 2010
Net income, as reported		$	27,213			$	22,272			$	87,010			$	84,838
Adjustments to net income:
Amortization of intangibles (a)			3,038				3,137				12,168				13,161
Amortization of financing costs (b)			3,535				3,440				14,077				15,790
Gain on extinguishment of debt (c)			—				—				—				(10,125	)
Gain on sale of non-strategic assets (d)			—				—				(7,719	)			(17,446	)
Tax effect of adjustments to net income (e)			(2,478	)			(2,479	)			(4,821	)			497
Non-GAAP adjusted net income		$	31,308			$	26,370			$	100,715			$	86,715
Net income per share, as reported
Basic		$	0.36			$	0.30			$	1.15			$	1.14
Diluted		$	0.35			$	0.30			$	1.12			$	1.14
Non-GAAP adjusted earnings per share
Basic		$	0.41			$	0.35			$	1.33			$	1.17
Diluted		$	0.40			$	0.35			$	1.30			$	1.16
Weighted average common shares used in calculation:
Basic			76,507				74,500				75,847				74,097
Diluted			77,522				75,412				77,632				74,675