Attached files

                                                      Exhibit 31.1

                              CERTIFICATION

I, Helena R. Santos, certify that:

1.  I have reviewed this report on Form 10-Q for the quarter ended
December 31, 2010 of Scientific Industries, Inc., a smalller reporting
company (the "Registrant");

2.  Based on my knowledge, this report does not contain any untrue
statement of a material fact or omit to state a material fact necessary
to make the statements made, in light of the circumstances under which
such statements were made, not misleading with respect to the period
covered by this report;

3.  Based on my knowledge, the financial statements, and other financial
information included in this report, fairly present in all material
respects the financial condition, results of operations and cash flows
of the Registrant as of, and for, the periods presented in this report;

4.  I am responsible for establishing and maintaining disclosure controls
and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)
and internal control over financial reporting (as defined in Exchange
Act Rules 13a-15 (f) and 15d-15(f) for the Registrant and have:

   a)   Designed such internal disclosure and procedures, or caused such
        controls and procedures to be designed under my supervision, to
        ensure that material information relating to the Registrant,
        including its consolidated subsidiaries, is made known to me by
        others within those entities, particularly during the period in
        which this report is being prepared;
   b)   Designed such internal control over financial reporting, or caused
        such internal control over financial reporting to be designed under
        my supervision, to provide reasonable assurance, regarding the
        reliability of financial reporting and the preparation of financial
        statements for external purposes in accordance with generally
        accepted accounting principles;
   c)   Evaluated the effectiveness of the Registrant's disclosure controls
        and procedures and presented in this report my conclusions about
        the effectiveness of the disclosure controls and procedures, as of
        the end of the period covered by this report based on such
        evaluation; and
   d)   Disclosed in this report any change in the Registrant's internal
        control over financial reporting that occurred during the
        Registrant's most recent fiscal quarter that has materially
        affected, or is reasonably likely to affect, the Registrant's
        internal control over financial reporting; and

5.  I have disclosed, based on my most recent evaluation of internal
controls over financial reporting, to the Registrant's auditors and the
audit committee of the Registrant's board of directors (or persons
performing the equivalent functions):

   a)   All significant deficiencies and material weaknesses in the design
        or operation of internal controls over financial reporting which
        are reasonably likely to adversely affect the Registrant's ability
        to record, process, summarize and report financial information; and







   b)   Any fraud, whether or not material, that involves management or
        other employees who have a significant role in the Registrant's
        internal controls over financial reporting.

February 11, 2011



/s/ Helena R. Santos
____________________
Helena R. Santos
Chief Executive Officer and Chief Financial Officer