Exhibit 99.1

UNITED STATES BANKRUPTCY COURT
DISTRICT OF DELAWARE

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — May 31, 2010

MONTHLY OPERATING REPORT
File with Court and submit copy to United States Trustee within 20 days after end of month

Submit copy of report to any official committee appointed in the case.

Document

Explanation

Affidavit/Supplement

REQUIRED DOCUMENTS

Form No.

Attached

Attached

Attached

Schedule of Cash Receipts and Disbursements

MOR-1

X

Bank Reconciliation (or copies of debtor’s bank reconciliations)

MOR-1a

X

Schedule of Professional Fees Paid

MOR-1b

X

Copies of bank statements

Cash disbursements journals

Statement of Operations

MOR-2

X

Balance Sheet

MOR-3

X

Status of Postpetition Taxes

MOR-4

X

Copies of IRS Form 6123 or payment receipt

Copies of tax returns filed during reporting period

Summary of Unpaid Postpetition Debts

MOR-4

X

Listing of aged accounts payable

MOR-4

X

Accounts Receivable Reconciliation and Aging

MOR-5

X

Debtor Questionnaire

MOR-5

X

I declare under penalty of perjury (28 U.S.C. Section 1746) that this report and the attached documents are true and correct to the best of my knowledge and belief.

Signature of Debtor				Date
Signature of Joint Debtor				Date
/s/ David Becker   Signature of Authorized Individual*				21-Jun-10   Date
David Becker   Printed Name of Authorized Individual				EVP, CFO and Acting President and CEO   Title of Authorized Individual

MOR
(04/07)

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

MOR 1

		Current Month								Cumulative Filing to Date
		Actual				Forecast				Actual				Forecast
Beginning Date		3-May-10				3-May-10				3-May-10				3-May-10
Ending Date		30-May-10				30-May-10				30-May-10				30-May-10
Cash — Beginning Balance		$	5,257,718			$	5,255,857			$	5,257,718			$	5,255,857
Receipts
Lockbox		$	82,435			$	127,550			$	82,435			$	127,550
Misc Deposit		$	36,567							$	36,567
(Item 3)
Total Receipts		$	119,003			$	127,550			$	119,003			$	127,550
Operating Disbursements
Broadpoint		$	0			$	(100,000	)		$	0			$	(100,000	)
Cardinal Co-Pay Redemptions		$	0			$	0			$	0			$	0
Dr Directory		$	0			$	(74,160	)		$	0			$	(74,160	)
Legal & Deal fees		$	0			$	(150,000	)		$	0			$	(150,000	)
Payroll		$	(260,909	)		$	(248,353	)		$	(260,909	)		$	(248,353	)
Severance		$	0			$	0			$	0			$	0
Vacation Payout		$	0			$	0			$	0			$	0
Invoices in A/P Aging		$	(164,286	)		$	(260,126	)		$	(164,286	)		$	(260,126	)
Misc (TX rent, Insurance, ICS)		$	(33,373	)		$	(75,000	)		$	(33,373	)		$	(75,000	)
Other		$	(3,548	)		$	(140,000	)		$	(3,548	)		$	(140,000	)
(Item 3)
Total Operating Disbursements		$	(462,116	)		$	(1,047,639	)		$	(462,116	)		$	(1,047,639	)
Net Operating Cash Flow		$	(343,113	)		$	(920,089	)		$	(343,113	)		$	(920,089	)
Non-Operating Disbursements
Capex
Professional Fees
Total Non-Operating Disbursements		$	0			$	0			$	0			$	0
Net Operating Cash Flow Before Financing		$	(343,113	)		$	(920,089	)		$	(343,113	)		$	(920,089	)
Financing Activities
Interest Payments
Financing Activities		$	0			$	0			$	0			$	0
Cash Flow		$	(343,113	)		$	(920,089	)		$	(343,113	)		$	(920,089	)
Ending Cash Balance (per books)		$	4,914,605			$	4,335,768			$	4,914,605			$	4,335,768

DISBURSEMENTS FOR CALCULATING U.S. TRUSTEE QUARTERLY FEES: (FROM CURRENT MONTH ACTUAL COLUMN)

TOTAL DISBURSEMENTS		$	(462,116	)
LESS: TRANSFERS TO DEBTOR IN POSSESSION ACCOUNTS			0
PLUS: ESTATE DISBURSEMENTS MADE BY OUTSIDE SOURCES (i.e. from escrow accounts)			0
TOTAL DISBURSEMENTS FOR CALCULATING U.S. TRUSTEE QUARTERLY FEES		$	(462,116	)

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

Disbursements Journal

Checks cut during period
GL Posting				Checkbook				CM Trx
Date		Source Document		Amount				Number				Voided		Paid ToRcvd From
5/5/2010		PMCHK		$	159.30				2489			No		Lifework Strategies
5/5/2010		PMCHK		$	38,869.78				2490			No		United Healthcare Insurance Co.
5/5/2010		PMCHK		$	2,245.88				2491			No		UNUM Life Insurance
5/5/2010		PMCHK		$	1,449.16				2492			No		VSP - (AT)
5/6/2010		PMCHK		$	0.00				2493			Yes		ExecuSuites I-270, Inc.
5/6/2010		PMCHK		$	0.00				2494			Yes		ExecuSuites I-270, Inc.
5/6/2010		PMCHK		$	3,250.00				2495			No		ExecuSuites I-270, Inc.
5/20/2010		PMCHK		$	2,894.02				2496			No		ADP
5/20/2010		PMCHK		$	1,000.00				2497			No		American Stock Transfer & Trust Co
5/20/2010		PMCHK		$	688.84				2498			No		David Becker
5/20/2010		PMCHK		$	3,385.25				2499			No		Robin N. Belsaas
5/20/2010		PMCHK		$	8,304.92				2500			No		Brad Cole
5/20/2010		PMCHK		$	100.00				2501			No		Commonwealth of PA/DRP
5/20/2010		PMCHK		$	183.42				2502			No		Department of Veterans Affairs
5/20/2010		PMCHK		$	1,480.97				2503			No		Gary Herman
5/20/2010		PMCHK		$	650.00				2504			No		Christine Higgins
5/20/2010		PMCHK		$	156.12				2505			No		Iron Mountain
5/20/2010		PMCHK		$	1,566.98				2506			No		Montgomery County, MD
5/20/2010		PMCHK		$	22.06				2507			No		Nevada Department of Taxation
5/20/2010		PMCHK		$	149.22				2508			No		Prostar Services, Inc
5/20/2010		PMCHK		$	200.00				2509			No		State of New Jersey Div
5/20/2010		PMCHK		$	179.03				2510			No		New Jersey Wraparound Drug Rebate
5/20/2010		PMCHK		$	132.08				2511			No		State of Washington
5/20/2010		PMCHK		$	83.91				2512			No		State of New Jersey Dept Health/Senior Serv
5/20/2010		PMCHK		$	10.44				2513			No		State of New Jersey PAAD Drug Rebate
5/20/2010		PMCHK		$	0.00				2514			Yes		Treasurer State of Maine
5/20/2010		PMCHK		$	1,584.79				2515			No		United States Treasury
5/20/2010		PMCHK		$	408.61				2516			No		Verizon Wireless
5/20/2010		PMCHK		$	10.44				2517			No		Wisconsin Dept of Health
5/20/2010		PMCHK		$	447.71				2518			No		Dr. Donald J. Treacy
5/27/2010		PMCHK		$	0.00				2519			Yes		AT&T
5/27/2010		PMCHK		$	3,136.45				2520			No		Robin N. Belsaas
5/27/2010		PMCHK		$	0.00				2521			Yes		Christine Higgins
5/27/2010		PMCHK		$	1,685.00				2522			No		Pure Compliance
5/27/2010		PMCHK		$	3,250.00				2523			No		RX Sample Solution
5/27/2010		PMCHK		$	1,785.59				2524			No		Marcus Schestopol
5/27/2010		PMCHK		$	50.00				2525			No		Shred-it USA, DBA Shred-it Dallas
5/27/2010		PMCHK		$	81,035.25				2526			Yes		Travelers (voided in June)
5/27/2010		PMCHK		$	3,730.38				2527			No		Dr. Donald J. Treacy
5/27/2010		PMCHK		$	0.00				2528			Yes		WorldWide express
				$	164,285.60			Checks Cut

Debits to bank other than checks
Transaction												Customer
Date		Description		Amount				Bank Ref#				Ref. #				Text
5/7/2010		ACH DEBIT		$	884.25				3309				0			ADP PAYROLL FEES ADP - FEES MIDDLEBROOK PHARMA. IN
5/10/2010		ACH DEBIT		$	33,339.17				1700				0			AMERICAN UNITED PENSIONPMT G30349MIDDLEBROOK PHAR
5/12/2010		WIRE TRANSFER DEBIT		$	66,212.14				2161				0			WIRE OUT 100512L1B77D1C000218201013201402;BNF ADP TAX SVCS INC. REV. WIRE IMPOUND;REF 050
5/13/2010		WIRE TRANSFER DEBIT		$	47,996.13				2007				0			WIRE OUT 100513L1B77D1C000212201013301254;BNF ADP INC FUNDSMGMT;OBI ID# 557YP 7132090VV;
5/17/2010		ACH DEBIT		$	6,320.76				652				0			AMERICAN UNITED PENSIONPMT G30349MIDDLEBROOK PHAR
5/18/2010		ACH DEBIT		$	442.02				332				0			TUC 613-591-9800 PURCHASE 708648894
5/21/2010		ACH DEBIT		$	766.94				1687				0			ADP PAYROLL FEES ADP - FEES MIDDLEBROOK PHARMA. IN
5/24/2010		ACH DEBIT		$	0.00				1345				0			ADP PAYROLL FEES ADP - FEES MIDDLEBROOK PHARMA, IN
5/24/2010		ACH DEBIT		$	122.59				1344				0			ADP PAYROLL FEES ADP - FEES MIDDLEBROOK PHARMA, IN
5/26/2010		SERVICE CHARGE		$	1,264.41				13651				0			ANALYSIS SERVICE CHARGE
5/26/2010		WIRE TRANSFER DEBIT		$	68,812.34				2857				0			WIRE OUT 100526L1B77D1C000439201014601951;BNF ADP TAX SVCS INC. REV. WIRE IMPOUND;REF 575
5/27/2010		WIRE TRANSFER DEBIT		$	38,228.74				2479				0			WIRE OUT 100527L1B77D1C000246201014701597;BNF ADP INC FUNDSMGMT;OBI ID# 557YP 7186921VV;
5/28/2010		ACH DEBIT		$	67.65				1767				0			ADP PAYROLL FEES ADP - FEES MIDDLEBROOK PHARMA. IN
5/28/2010		WIRE TRANSFER DEBIT		$	33,372.85				2391				0			WIRE OUT 100528L1B77D1C000192201014801470;BNF MAGUIRE PARTNERS SOLONA LP;OBI MIDDLEBROOK
				$	297,829.99			Debits to Bank other than Checks
				$	462,115.59			total disbursements
Checks cleared by bank:
5/3/2010		DEBIT MEMO		$	397.86				25				0			CONTROL DISBURSEMENT
5/6/2010		DEBIT MEMO		$	180.00				8				0			CONTROL DISBURSEMENT
5/7/2010		DEBIT MEMO		$	107.06				8				0			CONTROL DISBURSEMENT
5/10/2010		DEBIT MEMO		$	1,449.16				11				0			CONTROL DISBURSEMENT
5/12/2010		DEBIT MEMO		$	44,365.66				14				0			CONTROL DISBURSEMENT
5/18/2010		DEBIT MEMO		$	159.30				140				0			CONTROL DISBURSEMENT
5/24/2010		DEBIT MEMO		$	11,500.00				20				0			CONTROL DISBURSEMENT
5/25/2010		DEBIT MEMO		$	22.06				96				0			CONTROL DISBURSEMENT
5/26/2010		DEBIT MEMO		$	8,437.00				16				0			CONTROL DISBURSEMENT
5/27/2010		DEBIT MEMO		$	2,584.79				18				0			CONTROL DISBURSEMENT
5/28/2010		DEBIT MEMO		$	9,099.08				52				0			CONTROL DISBURSEMENT
				$	78,301.97

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

See bank reconciliation in separate attachment *

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

SCHEDULE OF PROFESSIONAL FEES AND EXPENSES PAID
This schedule is to include all retained professional payments from case inception to current month

Amount

Check

Amount Paid

Year-To-Date

Payee

Period Covered

Approved

Payor

Number

Date

Fees

Expenses

Fees

Expenses

none in May

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

				May				Cumulative
				2010				Filing to Date
45000		Gross Sales		$	253,103			$	253,103
45100		Chargebacks			(2,531	)			(2,531	)
45200		Medicaid Rebates			(8,371	)			(8,371	)
45300		Returns			(15,186	)			(15,186	)
45400		Cash Discounts			(5,062	)			(5,062	)
45500		Wholesaler Rebates			(13,568	)			(13,568	)
45600		Product Shortage Deductions			492				492
45700		Coupon POS Discounts			92,152				92,152
		Revenue			301,029				301,029
55101		COGS — Cost of Goods Sold			11,433				11,433
50100		COGS — Scrap			375,218				375,218
51000		COGS — Mfg Equipment Depreciation			21,675				21,675
56000		COGS — Keflex Royalties			4,658				4,658
		Cost of Goods Sold			412,984				412,984
60010		Salaries Expense			228,581				228,581
60030		Severance Expense			14,292				14,292
60380		Commissions			0				0
		Salaries, Bonus & Temp Labor			242,873				242,873
60300		Benefits			1,748				1,748
60310		Employee Benefit Programs Exp			0				0
60320		Health Insurance Expense			(2,120	)			(2,120	)
60330		Payroll Tax Expense			16,542				16,542
62010		Recruiting			0				0
62020		Relocation			0				0
60370		Professional Development Exp			0				0
		Benefits, Taxes, Recruiting & Relo			16,170				16,170
		Subtotal: Salaries & Benefits			259,043				259,043
60015		Stock Based Comp Exp: Employee			0				0
60016		Stock Based Comp Exp: Non-Employee/Consultant			(40,272	)			(40,272	)
		Stock-Based Compensation			(40,272	)			(40,272	)
66010		Advertising Expense			0				0
66020		Dues and Subscriptions Exp			846				846
66110		Meetings & Conferences			0				0
		Marketing & Advertising			846				846
63020		Meals and Entertainment Exp			545				545
63030		Travel Expense			15,432				15,432
		Travel & Entertainment			15,977				15,977

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

				May				Cumulative
				2010				Filing to Date
64020		LAN,Computer, Alarm Exp.			(5,208	)			(5,208	)
64030		Office Cleaning Exp			0				0
65010 + (67200)		Maintenance & Repair Expense			211				211
65021		Building Maintenance Expense			0				0
65030		Rent or Lease Expense			49,707				49,707
65040		Rental and Lease — Equip Exp.			0				0
65060		Utilities Expense			0				0
64090		Kitchen Supplies Expense			149				149
65070		Telephone Expense			5,067				5,067
		Facilities and Equipment Related			49,926				49,926
60340		Insurance Expense-Wkers Comp			0				0
64110 + (65050)		Insurance Expense			84,092				84,092
		Insurance			84,092				84,092
65102		Distribution Expense — ICS			99,497				99,497
		Distribution Expense			99,497				99,497
64050		Office Supplies & Expense			796				796
64070		Printing and Reproduction Exp			508				508
64071		Publications & Subscriptions			0				0
64060		Postage Expense			0				0
67100		Freight Expense			(32	)			(32	)
68010 + (64080)		General LAB Supplies & Exp.			(72	)			(72	)
79010		Other Expenses			0				0
		Office & General Lab Supplies			1,200				1,200
61010		Consulting Fees Expense			1,324				1,324
69010		Legal Expense			742,239				742,239
		Consulting & Legal Fees			743,563				743,563
69030		Patents			45,000				45,000
69020		Compliance Fees			0				0
72500		Penalties & Fines			0				0
70300 + (73000)		Licensing & Filing Expense			51,587				51,587
		Patents & Licensing			96,587				96,587
64075		SEC Filing Expense			5,162				5,162
64215		Annual Report Expense			0				0
69040		Auditing & Accounting			0				0
65071		Newswire Expense			487				487
65072		Audio Conference Call Expense			99				99
65073		Web Casting Expense			0				0
64040		Payroll Service Fee			7,601				7,601
64210		Bank Charges			1,332				1,332

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

				May				Cumulative
				2010				Filing to Date
66015		Stock Transfer Fees			9,005				9,005
66016		Trustee stock plan administration			0				0
		Audit, IR & Financial Fees			23,687				23,687
65090		Personal Prop.Tax Exp-Equipmen			0				0
65091		Franchise Tax			1,066				1,066
79030		Other Taxes			7				7
95016		Taxes-Real Estate			0				0
		Non-Income Taxes			1,073				1,073
66030		Gifts Expense			0				0
		Gifts and Charitable Contributions			0				0
70100		Depreciation Expense			161,405				161,405
70200		Amortization Expense			209,871				209,871
		Depreciation and Amortization			371,276				371,276
72000		Outside Directors			20,917				20,917
		Director and SAB Fees			20,917				20,917
		Subtotal: FTE Expenses			1,727,411				1,727,411
61029		Market Research			0				0
61030		Samples — Reps			0				0
61037		Field Aids			0				0
61039		Coupons			3,250				3,250
61040		Tokens/Direct Promotions			0				0
66200		Trade Association			0				0
61041		MD Telemarketing			0				0
61042		Journal Ads			0				0
61045		Public Relations			0				0
61047		Ad Agency Fees			0				0
61048		Managed Care			0				0
61050		CSO Expense			50,000				50,000
61051		Trade Shows			5,000				5,000
63010		Auto Expense			(9,080	)			(9,080	)
61054		Launch Meeting			0				0
		Marketing Costs			49,170				49,170

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

				May				Cumulative
				2010				Filing to Date
82000		Development Materials			0				0
83000 +(83100)		Contract R & D			114,706				114,706
84000		Project Consultants			0				0
		Direct Project Costs			114,706				114,706
		Total Expenses			2,304,270				2,304,270
		Income (Loss) from Operations			(2,003,241	)			(2,003,241	)
90100		Interest Income			199				199
		Interest Income			199				199
95020		Interest Expense			0				0
95050		Gain or (Loss) on sale of assets			2,905				2,905
		Other income (expense)			2,905				2,905
		Net Income (Loss) Before Taxes			(2,000,137	)			(2,000,137	)
		Net Income (Loss)		$	(2,000,137	)		$	(2,000,137	)

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

		Current				Petition
		Month				Date
10105 - SVB Operating Account		$	4,914,605			$	5,257,718
10215 - SVBAM Cash			0				0
Cash & Cash Equivalents			4,914,605				5,257,718
11300 - A/R Product Sales			605,932				437,031
11304 - A/R (Contra) - Cash Discounts			(11,166	)			(8,929	)
11305 - A/R (Contra) accrued chargebacks			(254,924	)			(259,023	)
11307 - A/R (Contra) - accrued wholesaler rebates			(668,056	)			(659,567	)
Accounts Receivable			(328,214	)			(490,487	)
12100 - Inventory - Raw Materials			739,348				602,263
12110 - Inventory - Bulk			660,305				660,305
12120 - Inventory - Finished Goods			3,331,764				3,343,197
12200 - Inventory - Reserve for obsolete/slow moving			(2,392,607	)			(2,392,607	)
Inventory			2,338,810				2,213,158
11030 - Other Receivables			15,329				15,329
14010 - Prepaid Expenses			366,697				863,286
14020 - Prepaid Rent			33,373				36,623
14030 - Prepaid SAB/BOD			0				0
14050 - Prepaid Insurance			416,210				500,302
14115 - Prepaid Travel			0				0
14200 - Employee Advances			(16	)			0
14500 - Prepaid Samples			2,391,421				1,981,566
Prepaid and Other Current Assets			3,223,013				3,397,106
17100 - Furniture & Fixtures			613,506				834,472
17115 - Equipment -Pharm Development			3,150,304				3,200,488
17130 - Equipment-Telephone System			198,613				244,938
17140 - Equipment-Security System			16,420				19,920
17150 - LAN & Phone Wiring-Equip			48,793				48,793
17200 - Automobiles			0				0
17400 - Leasehold Improvements			6,849,683				9,239,394
17600 - Computer Equipment			230,844				753,769
18100 - Accum. Deprec. - F&F			(593,821	)			(811,507	)
18115 - Acc Dep- Equip-Pharm Development			(1,631,286	)			(1,664,702	)
18130 - Accum. Deprec. - Telephone			(173,529	)			(218,054	)
18140 - Accum. Deprec. - Security Sys			(16,420	)			(19,920	)
18150 - Accum. Deprec. - LAN			(46,910	)			(46,775	)
18200 - Accum. Deprec. - Automobil			0				0
18400 - Accum. Amortization - Leasehol			(6,830,756	)			(9,220,282	)
18600 - Accum. Deprec. - Computer			(117,673	)			(479,686	)
Property and Equipment, net			1,697,768				1,880,848
10130 - Allfirst-CD/loan collateral			0				0
Restricted Cash			0				0
19000 - Deposits			525,714				533,714
19005 - Deposits-Coupon Program			145,666				146,866
Deposits and Other Assets			671,380				680,580
17800 - Intellectual Property			120,000				120,000
17810 - Keflex Acquired Intangibles			11,757,529				11,757,529
18800 - Accum. Amort. - Intellectual P			(120,000	)			(120,000	)
18810 - Accum. Amort - Keflex Intangibles			(2,733,089	)			(2,523,218	)
Intangible Assets, net			9,024,440				9,234,311
Total Assets		$	21,541,803			$	22,173,234

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

		Current				Petition
		Month				Date
20000 - Accounts Payable - post-petion			(178,584	)			—
20100 - Accrued Payables			0				—
21110 - Accrued Severance			0				—
21201 - Accrued Payable to Lilly			(4,658	)			—
21210 - Accrued Professional Fees			(20,917	)			—
21250 - Accrued R&D Costs			0				—
21275 - Accrued Keflex Copay Assistance			(206	)			—
21276 - Accrued Moxatag Copay Assistance			(3,355	)			—
21281 - Accrued Medicaid Rebates Payable			(8,371	)			—
21282 - Accrued Returns			(15,186	)			—
21290 - Other Accrued Expenses			(482,498	)			—
23200 - Wages Payable			(15,831	)			—
23215 - Accrued Commissions			0				—
23260 - Relocation Accrual			0				—
23620 - Employee Benefits Pay-401k			(6,321	)			—
23650 - Employee Benefits - Flex Spending			(792	)			—
25000 - Other Current Liabilities			0				—
Accounts Payable and Accrued Expenses - Post-Petition			(736,719	)			0
20000 - Accounts Payable - pre-petion			(2,247,920	)			(1,214,588	)
21110 - Accrued Severance			(279,793	)			(281,258	)
21201 - Accrued Payable to Lilly			(5,252	)			(5,252	)
21210 - Accrued Professional Fees			(244,917	)			(199,917	)
21250 - Accrued R&D Costs			(136,067	)			(136,067	)
21275 - Accrued Keflex Copay Assistance			(1,857	)			(9,276	)
21276 - Accrued Moxatag Copay Assistance			(3,615,540	)			(3,705,035	)
21281 - Accrued Medicaid Rebates Payable			(437,995	)			(563,001	)
21282 - Accrued Returns			(1,958,072	)			(1,945,797	)
21290 - Other Accrued Expenses			(119,107	)			(292,773	)
23200 - Wages Payable			(306,521	)			(306,521	)
23215 - Accrued Commissions			0				(0	)
23260 - Relocation Accrual							0
23620 - Employee Benefits Pay-401k			0				(33,339	)
23650 - Employee Benefits - Flex Spending			(3,015	)			(3,899	)
25000 - Other Current Liabilities			(4,823,076	)			(4,810,772	)
Accounts Payable and Accrued Expenses - Pre-Petition			(14,179,132	)			(13,507,496	)
27051 - Deferred contract revenue - non-current PAR (pre-petition)			(11,625,000	)			(11,625,000	)
Deferred Contract Revenue - non-current (pre-petition)			(11,625,000	)			(11,625,000	)
27010 - Deferred Rent			(18,963	)			(18,340	)
Def Credit on Lease Concession			(18,963	)			(18,340	)
27000 - Other long term liabilities			0				0
Other long-term liabilities			0				0
31000 - Common Stock			(865,119	)			(865,119	)
31100 - Additional Paid-in Capital			(333,148,706	)			(333,188,978	)
31110 - APIC-BCF			20,907,620				20,907,620
APIC			(312,241,086	)			(312,281,358	)
32000 - Retained Earnings			299,240,744				299,240,744
YTD P&L			18,883,473				16,883,336
Accumulated Deficit			318,124,217				316,124,080
Stockholders’ Equity			5,018,012				2,977,602
Liabilities & Stockholders’ Equity		$	(21,541,803	)		$	(22,173,234	)

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

Other Post-petition liabilities
Professional bankruptcy fees - KCC estimate		$	45,000.00
Professional bankruptcy fees - creditors’ committee cousel & FA			300,000.00
DoctorDirectory (May estimate)			50,000.00
ICS (May estimate)			51,603.26
Other miscellaneous May accruals - no invoices yet			35,774.89
		$	482,378.15

In re: MiddleBrook Pharmaceuticals, Inc.		Case No. 10-11485
Debtor		Reporting Period: May 1 — 31, 2010

STATUS OF POSTPETITION TAXES

The beginning tax liability should be the ending liability from the prior month or, if this is the first report, the amount should be zero. Attach photocopies of IRS Form 6123 or payment receipt to verify payment or deposit of federal payroll taxes. Attach photocopies of any tax returns filed during the reporting period.

		Beginning				Amount																Ending
		Tax				Withheld or				Amount				Date				Check No.				Tax
		Liability				Accrued				Paid				Paid				or EFT				Liability
Federal
Withholding			0																				0
FICA-Employee			0			see attached ADP report for payroll taxes due and paid. **																	0
FICA-Employer			0																				0
Unemployment			0																				0
Income			0																				0
Other:			0																				0
Total Federal Taxes			0																				0
State and Local
Withholding			0																				0
Sales			0																				0
Excise			0								132.08												0			Washington State
Unemployment			0																				0
Real Property			0																				0
Personal Property			0								676.39												0			MD property tax - received letter for adjusted amount due
Other:			0																				0
Total State and Local			0				0				808.47				0				0				0
Total Taxes			0				0				808.47				0				0				0