Attached files

file filename
EX-32 - EXHIBIT 32 - ARQULE INCa2196767zex-32.htm
EX-31.2 - EXHIBIT 31.2 - ARQULE INCa2196767zex-31_2.htm
EX-31.1 - EXHIBIT 31.1 - ARQULE INCa2196767zex-31_1.htm
10-K - 10-K - ARQULE INCa2196767z10-k.htm

QuickLinks -- Click here to rapidly navigate through this document


EXHIBIT 23.1


CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

        We hereby consent to the incorporation by reference in the Registration Statements on Form S-8 (File Nos. 333-161115, 333-161113, 333-130159 and 333-148793) and Form S-3 (File No. 333-143162) of ArQule, Inc., of our report dated March 2, 2010 relating to the financial statements and the effectiveness of internal control over financial reporting, which appears in this Form 10-K.

/s/ PricewaterhouseCoopers LLP

Boston, Massachusetts
March 2, 2010




QuickLinks

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM