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10-K - FORM 10-K - PHARMACEUTICAL PRODUCT DEVELOPMENT INCd10k.htm
EX-10.275 - TOPO MASTER SERVICES AGREEMENT - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex10275.htm
EX-10.274 - TOPO DEVELOPMENT AND LICENSE AGREEMENT - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex10274.htm
EX-10.273 - MULDELTA MASTER SERVICES AGREEMENT - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex10273.htm
EX-10.272 - MULDELTA DEVELOPMENT AND LICENSE AGREEMENT - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex10272.htm
EX-32.2 - CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350 - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex322.htm
EX-32.1 - CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350 - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex321.htm
EX-31.2 - CERTIFICATION OF CHIEF FINANCIAL OFFICER - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex312.htm
EX-23.1 - CONSENT OF DELOITTE & TOUCHE LLP - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex231.htm
EX-31.1 - CERTIFICATION OF CHIEF EXECUTIVE OFFICER - PHARMACEUTICAL PRODUCT DEVELOPMENT INCdex311.htm

Exhibit 21

Pharmaceutical Product Development, Inc., and Subsidiaries

Subsidiaries

The subsidiaries of Pharmaceutical Product Development, Inc., as of February 18, 2010, are as follows:

 

    

Name of Subsidiary

  

Jurisdiction of Incorporation
Or Organized in

1.

   Applied Bioscience International, LLC    Delaware

2.

   PPD Global Central Labs, LLC    Kentucky

3.

   PPD Preclinical, LLC (Formerly PRC, LLC)    North Carolina

4.

   PPD Aeronautics, LLC    North Carolina

5.

   PPD Virtual, Inc.    North Carolina

6.

   APBI Finance Corporation    Delaware

7.

   APBI Holdings, LLC    North Carolina

8.

   Development Partners, LLC    Delaware

9.

   PPD GP, LLC    Delaware

10.

   PPD Holdings, LLC    Delaware

11.

   PPD UK Holdings Ltd    United Kingdom

12.

   Genupro, Inc.    North Carolina

13.

   PPD Development, LP    Texas

14.

   ATP, LLC    North Carolina

15.

   Pharmaco Investments, Inc.    Delaware

16.

   PPD International Holdings, Inc.    Delaware

17.

   PPD France SNC    France

18.

   PPD Scandinavia AB    Sweden

19.

   Pharmaceutical Product Development Spain SL    Spain

20.

   PPD do Brasil-Suporte a Pesquisa Clinica Ltda.    Brazil

21.

   PPD Argentina, S.A.    Argentina

22.

   PPD International Holdings, Inc. y Compania Limitada    Chile

23.

   Pharmaceutical Product Development South Africa (Pty) Ltd    South Africa

24.

   PPD Canada, Ltd.    Canada

25.

   PPD Australia Pty Ltd    Australia

26.

   PPD International Holdings GmbH    Germany

27.

   PPD Germany GmbH    Germany

28.

   PPD Poland Sp. Z o.o.    Poland

29.

   PPD Czech Republic s.r.o.    Czech Republic

30.

   PPD Germany GmbH & Co KG    Germany

31.

   PPD Hungary Research & Development Limited    Hungary

32.

   PPD Italy S.r.l.    Italy

33.

   PPD Mexico, S.A. de C.V.    Mexico

34.

   PPD Development (Thailand) Co., Ltd    Thailand

35.

   PPD Japan K.K.    Japan

36.

   PPD Global, Ltd    United Kingdom

37.

   Clinical Technology Centre (International) Ltd    United Kingdom

38.

   Cambridge Applied Nutrition Toxicology & Biosciences Ltd    United Kingdom

39.

   Clinical Science Research International Ltd    United Kingdom

40.

   Leicester Clinical Research Centre Ltd    United Kingdom

41.

   Chelmsford Clinical Trials Unit Ltd    United Kingdom

42.

   Gabbay Ltd    United Kingdom

43.

   Data Analysis & Research (DAR) Ltd    Scotland

 

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44.

   PPD Global Central Labs BVBA    Belgium

45.

   PPD Development (S) Pte Limited    Singapore

46.

   PPD Development (HK) Limited    Hong Kong

47.

   PPD (Netherlands) BV    Netherlands

48.

   PPD Pharmaceutical Development India Private Limited    India

49.

   River Ventures, LLC    North Carolina

50.

   PPD Slovak Republic s.r.o.    Slovak Republic

51.

   PPD Peru S.A.C.    Peru

52.

   PPD Vaccines and Biologics, LLC    Pennsylvania

53.

   PPD Pharmaceutical Development (Beijing) Co., Ltd    China

54.

   Greenbird Limited    Cyprus

55.

   PPD Development Ireland Ltd    Ireland

56.

   Limited Liability Company PPD Development (Smolensk)    Russia

57.

   PPD Global Central Labs (S) Pte. Ltd.    Singapore

58.

   Limited Liability Company Contract Research Organization Innopharm – Ukraine    Ukraine

59.

   PPD Dermatology, Inc.    Delaware

60.

   PPD Therapeutics, Inc.    Delaware

61.

   AbC.R.O., Inc.    Virginia

62.

   PPD BULGARIA EOOD    Bulgaria

63.

   BioDuro, LLC    Delaware

64.

   BioDuro (Mauritius)    Mauritius

65.

   BIODURO (BAONUO) BEIJING TECHNOLOGY CO., LTD.    Beijing, China

66.

   Excel Pharmastudies, Inc.    Cayman

67.

   Excel (Beijing) Medical Technology Co., LTD.    Beijing, China

68.

   EXCEL PHARMASTUDIES TAIZHOU BIOMETRICS, INC.    Taizhou, China

69.

   EXCEL PHARMASTUDIES TAIZHOU VACCINE, INC.    Taizhou, China

70.

   Excel Pharmastudies (US), Inc.    California

71.

   PPD CT Investments LLP    United Kingdom

72.

   ABC.R.O. Bulgaria EAD    Bulgaria

73.

   ABC.R.O. Romania S.R.L.    Romania

74.

   AbC.R.O. d.o.o.    Croatia

75.

   AbC.R.O. Poland Sp. Z o.o.    Poland

76.

   Limited Liability Company ABC.R.O.    Russia

 

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Subsidiaries 1, 2, 3, 5, 52, 59, and 60 are wholly-owned subsidiaries of Pharmaceutical Product Development, Inc.

Subsidiaries 9 and 10 are wholly-owned subsidiaries of Subsidiary 1.

Subsidiary 12 is a wholly-owned subsidiary of Subsidiary 5.

Subsidiary 13 is owned 99.9% by Subsidiary 10 and 0.1% by Subsidiary 9.

Subsidiaries 4, 6, 7, 14, 15, 16, and 49 are wholly-owned subsidiaries of Subsidiary 13.

Subsidiaries 8, 18, 23, 24, 25, 26, 32, 35, and 61 are wholly-owned subsidiaries of Subsidiary 16.

Subsidiary 17 is owned 99.9999% by Subsidiary 16 and 0.001% by Subsidiary 1.

Subsidiary 19 is owned 99.231 % by Subsidiary 16 and 0.769% by Subsidiary 13.

Subsidiary 20 is owned 99.99% by Subsidiary 16 and 0.01% by Pharmaceutical Product Development, Inc.

Subsidiary 21 is owned 95% by Subsidiary 16 and 5% by Subsidiary 1.

Subsidiary 22 is owned 99% by Subsidiary 16 and 1% by Subsidiary 1.

Subsidiaries 27 and 28 are wholly-owned subsidiaries of Subsidiary 26.

Subsidiary 29 is owned 97.78% by Subsidiary 26 and 2.22% by Subsidiary 16.

Subsidiary 30 is owned 72% by Subsidiary 26 and 28% by Subsidiary 27.

Subsidiary 31 is owned 96.67% by Subsidiary 26 and 3.33% by Subsidiary 16.

Subsidiary 33 is owned 99.99% by Subsidiary 16 and 0.01% by Subsidiary 13.

Subsidiary 34 is owned 99.99% by Subsidiary 16 and 1 share is held by each of Subsidiary 7, Subsidiary 11, Subsidiary 36, Subsidiary 45, Subsidiary 46, and 1 individual.

Subsidiaries 36, 40, 41, 42, 43, 45, 47, 55, 57, 62, 63, and 66 are wholly-owned subsidiaries of Subsidiary 11.

Subsidiary 37 is owned 99% by Subsidiary 36 and 1% by Subsidiary 11.

Subsidiary 38 is owned 50% by Subsidiary 11 and 50% by Subsidiary 36.

Subsidiary 39 is a wholly-owned subsidiary of Subsidiary 36.

Subsidiary 44 is 99.9% owned by Subsidiary 11 and .1% by Subsidiary 36.

Subsidiary 46 is 50% owned by Subsidiary 45 and 50% by Subsidiary 1.

Subsidiary 48 is owned 99.99% by Subsidiary 11 and 0.01% by Subsidiary 36.

Subsidiary 50 is owned 85% by Subsidiary 11 and 15% by Subsidiary 36.

Subsidiary 51 is owned 99% by Subsidiary 16 and 1% by Subsidiary 1.

Subsidiary 53 is a wholly-owned subsidiary of Subsidiary 45.

Subsidiary 54 is owned 99.95% by Subsidiary 11 and 0.05% by Subsidiary 47.

Subsidiary 56 is a wholly-owned subsidiary of Subsidiary 54.

Subsidiary 58 is a wholly-owned subsidiary of Subsidiary 56.

Subsidiary 11 is 99.6% owned by Subsidiary 16 and 0.4% by Subsidiary 61.

Subsidiary 64 is wholly-owned subsidiary of Subsidiary 63.

Subsidiary 65 is wholly-owned subsidiary of Subsidiary 64.

Subsidiary 67 and 70 is wholly-owned subsidiary of Subsidiary 66.

Subsidiary 68 is 85% owned by Subsidiary 67 and 15% by a Chinese entity.

Subsidiary 69 is 80% owned by Subsidiary 67, 5% by Subsidiary 68, and 15% by a Chinese entity.

Subsidiary 71 is 80% owned by Subsidiary 6 and 20% owned by Subsidiary 16.

Subsidiaries 72, 74, and 75 are wholly-owned subsidiaries of Subsidiary 61.

Subsidiary 73 is 99.3% owned by Subsidiary 61 and 0.7% owned by Subsidiary 62.

Subsidiary 76 is 75% owned by Subsidiary 62 and 25% owned by Subsidiary 61.

 

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